Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Karel Souček"'
Autor:
Hana Kotasová, Michaela Capandová, Vendula Pelková, Jana Dumková, Zuzana Koledová, Ján Remšík, Karel Souček, Zuzana Garlíková, Veronika Sedláková, Anas Rabata, Petr Vaňhara, Lukáš Moráň, Lukáš Pečinka, Volodymyr Porokh, Martin Kučírek, Libor Streit, Josef Havel, Aleš Hampl
Publikováno v:
Tissue Eng Regen Med
BACKGROUND: The progenitors to lung airway epithelium that are capable of long-term propagation may represent an attractive source of cells for cell-based therapies, disease modeling, toxicity testing, and others. Principally, there are two main opti
Autor:
Lucie Jurečková, Veronika Pospíšilová, Petr Vaňhara, Aleš Hampl, Zuzana Holubcová, Vendula Pelková, Daniela Mináriková, Tomáš Bárta, Karel Souček, Dáša Bohačiaková, Volodymyr Porokh
Publikováno v:
Stem Cells and Development. 27:1077-1084
Chromosomal instability evoked by abnormalities in centrosome numbers has been traditionally considered as a hallmark of aberrant, typically cancerous or senescent cells. We have reported previously that pristine human embryonic stem cells (hESC) suf
Autor:
Tereza Suchankova, Karel Souček, Tomáš Soukup, Zuzana Kahounová, Alice Malenovská, Eva Slabáková, Ján Remšík, Jan Bouchal, Daniela Kurfürstová, Aleš Hampl, Zuzana Holubcová
Publikováno v:
Journal of assisted reproduction and genetics. 35(8)
PURPOSE: The purpose of the study was to determine whether the GDF-15 is present in follicular fluid; to evaluate if there is a relation between follicular and serum levels of GDF-15 and fertility status of study subjects; and to test whether granulo
Publikováno v:
Differentiation. 78:213-222
Survival and capability of cancer cells to form metastases fundamentally depend on interactions with their microenvironment. Secondary tumors originating from prostate carcinomas affect remodeling of bone tissue and can induce both osteolytic and ost
Publikováno v:
European Journal of Haematology. 83:35-47
The block of hematopoietic differentiation program in acute myeloid leukemia cells can be overcome by differentiating agent like retinoic acid, but it has several side effects. A study of other differentiation signaling pathways is therefore useful t
Autor:
Petr Dvořák, Jiří Pacherník, Viktor Horváth, Zuzana Holubcová, Jan Vondráček, Aleš Hampl, Vítězslav Bryja, Karel Souček, Lukas Cajanek
Publikováno v:
Cell Proliferation
Objectives: This article is to study the role of G1/S regulators in differentiation of pluripotent embryonic cells. Materials and methods: We established a P19 embryonal carcinoma cell-based experimental system, which profits from two similar differe
Publikováno v:
Differentiation. 72:23-31
The level of differentiation could influence sensitivity of colonic epithelial cells to various stimuli. In our study, the effects of TNF-alpha, inhibitors of arachidonic acid (AA) metabolism (baicalein, BA; indomethacin, INDO; niflumic acid, NA; nor
Publikováno v:
Blood Cells, Molecules, and Diseases. 26:395-406
ABSTRACT Retinoids are important agents which regulate differentiation and proliferation processes in various cell types, including cancer cells. Growth arrest and induction of terminal differentiation demonstrate the tumor-suppressive effects of ret
Publikováno v:
Prostate cancer and prostatic diseases. 15(4)
Deregulation of expression and function of cytokines belonging to the transforming growth factor-β (TGF-β) family is often associated with various pathologies. For example, this cytokine family has been considered a promising target for cancer ther
Publikováno v:
Molecular and cellular biochemistry. 330(1-2)
The treatment of human promyelocytic leukemia cell lines HL-60, and to some extent NB-4, with 1alpha,25-dihydroxyvitamin D(3) (VD3) induces differentiation toward the monocytic/macrophage lineage, demonstrated by the increased expression of CD11b and