Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Julia Jellusova"'
Autor:
Ju Liu, Yukai Jing, Lu Yang, Jiang Chang, Julia Jellusova, Na Li, Panpan Jiang, Lisa S. Westerberg, Anwei Chen, Cong-Yi Wang, Qiuyue Chen, Danqing Kang, Xi Luo, Chaohong Liu, Heather Miller, Quan Gong
Publikováno v:
Cellular and Molecular Life Sciences. 77:4379-4395
As an important chemokine receptor, the role of CX3CR1 has been studied extensively on the migration of lymphocytes including T and B cells. Although CX3CR1+ B cells have immune suppressor properties, little is known about its role on the regulation
Autor:
Julia Jellusova
Publikováno v:
Immunological reviewsREFERENCES. 295(1)
In response to mitogenic stimulation, B cells activate different pro-anabolic signaling pathways such as c-Myc- and mTORC1-dependent networks to satisfy the energetic demands of biomass synthesis and proliferation. In order to preserve viability and
Publikováno v:
The Journal of Immunology. 199:2998-3003
B cells contribute critically to an effective immune response by producing antigen-specific antibodies. During the immune response to so-called thymus dependent antigens, activated B cells seek T cell help and form germinal centers. In contrast, thym
Autor:
Matthew H. Cato, Parham Ramezani-Rad, James R. Woodgett, John R Apgar, Cindi Chen, Robert J. Benschop, Julia Jellusova, Adam D. Richardson, Robert C. Rickert, Elaine M Conner, Charlotte R Leung
Publikováno v:
Nature immunology
B cells predominate in a quiescent state until an antigen is encountered, which results in rapid growth, proliferation and differentiation of the B cells. These distinct cell states are probably accompanied by differing metabolic needs, yet little is
Autor:
Julia Jellusova
Publikováno v:
Immunology letters. 201
Mounting evidence demonstrates that specific metabolic adaptations are needed to support B cell development and differentiation and to enable B cells to thrive in different environments. Mitogen induced activation of intracellular signaling pathways
Autor:
Julia Jellusova, Robert C. Rickert
Publikováno v:
Critical reviews in biochemistry and molecular biology. 51(5)
B cell growth and proliferation is tightly regulated by signaling through the B cell receptor and by other membrane bound receptors responding to different cytokines. The PI3K signaling pathway has been shown to play a crucial role in B cell activati
Autor:
Joachim Gläsner, André Gessner, Selina Sitte, Ruggero Pardi, Florian Weisel, Julia Jellusova, Martina Panattoni
Publikováno v:
The Journal of Immunology. 188:2677-2686
Jun activation domain-binding protein 1 (JAB1) regulates ubiquitin-dependent protein degradation by deneddylation of cullin-based ubiquitin ligases and, therefore, plays a central role in regulating proliferation and apoptosis. Because these processe
Autor:
Julia Jellusova, Edward M. Conway, Ana V. Miletic, G. V. Baracho, Charlotte R. Lee, Robert C. Rickert, Matthew H. Cato
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 196(5)
Survivin is a member of the inhibitor of apoptosis family of proteins and a biomarker of poor prognosis in aggressive B cell non-Hodgkin’s lymphoma. In addition to its role in inhibition of apoptosis, survivin also regulates mitosis. In this articl
Autor:
Sung Hoon Cho, Mark Boothby, Lindsey Heffington, Robert C. Rickert, Ki Taek Nam, Julia Jellusova, Keunwook Lee, James W. Thomas, Ariel Raybuck
Publikováno v:
Blood. 122(14)
The mammalian target of rapamycin (mTOR), an essential serine/threonine kinase, functions in biochemically distinct multiprotein complexes, but little is known about roles of the complexes in B cells. The acutely rapamycin-sensitive mTOR complex 1 (m