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Autor:
Fenq-Qi Zhao, Ratan K. Choudhary
Publikováno v:
Current Stem Cell Research & Therapy. 17:207-213
Adult stem cells like mammary and mesenchymal stem cells have received significant attention because these stem cells possess therapeutic potential in treating many animal diseases. These cells can be administered in an autologous or allogenic fashio
Autor:
Myeonggyo Jeong, Bae-Hoon Kim, Tae-Gyun Woo, Heegyu Kim, Min-Ho Yoon, Hyunkee Lee, Soyeong Kim, Young-Ger Suh, Young Taek Han, Hwayoung Yun, Yeong Hye Park, Yonghoon Kwon, Jung-Hyun Cho, Bum-Joon Park, Soyoung Park, So-mi Kang
Publikováno v:
Molecular Cancer Research. 20:412-424
Loss of NF2 (merlin) has been suggested as a genetic cause of neurofibromatosis type 2 and malignant peripheral nerve sheath tumor (MPNST). Previously, we demonstrated that NF2 sustained TGFβ receptor 2 (TβR2) expression and reduction or loss of NF
Autor:
Brett D. Volmert, Kristen Ball, Wen Li, Natalia Pajares, Aaron H. Wasserman, Chao Zhou, Aitor Aguirre, Mitchell A. Gabalski, Yixuan Ming, Yonatan R. Lewis-Israeli, Weiyang Yang, Guangming Ni, Xanthippi Chatzistavrou, Jinyun Zou
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications
Nature Communications
Congenital heart defects constitute the most common human birth defect, however understanding of how these disorders originate is limited by our ability to model the human heart accurately in vitro. Here we report a method to generate developmentally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::143cb2c5f7d599574cbc708a1060ba8d
Autor:
Pablo Martín-Vasallo, Ricardo Gutiérrez, Deborah Rotoli, Julio Ávila, Manuel Morales, Lucio Díaz-Flores
Publikováno v:
J Histochem Cytochem
Glioma stem cells (GSCs) live in a continuous process of stemness reprogramming to achieve specific cell commitment within the so-called GSC niches, specifically located in periarteriolar regions. In this review, we analyze the expression levels, cel
In this study we utilised an in vitro model system to gain insight into the potential cellular interactions that quantum dot (QD) nanoparticles may experience while transiting the viable skin epidermis, and we consider the effects of UVB exposure. UV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9fceaefd1095189c87a9599f182e5c8
Publikováno v:
American Journal of Physiology-Cell Physiology
American Journal of Physiology-Cell Physiology, 2022, 322 (2), pp.C311-C325. ⟨10.1152/ajpcell.00256.2021⟩
American Journal of Physiology-Cell Physiology, 2022, 322 (2), pp.C311-C325. ⟨10.1152/ajpcell.00256.2021⟩
International audience; Mitochondria are essential to cell homeostasis, and alterations in mitochondrial distribution, segregation, and turnover have been linked to complex pathologies such as neurodegenerative diseases and cancer. Understanding how
Autor:
Yu-Han Chang, Po-Liang Lai, Ya-Hui Lin, Hsiang-Sheng Lee, Yelena V. Parfyonova, Mikhail Menshikov, Chin-Wei Chang, Nuong Thi Kieu Nguyen, Vu Anh Truong, Jaw Ching Wu, Yu-Chen Hu, Nam Ngoc Pham, Yi-Hao Chang, Chih-Che Shen, Mu-Nung Hsu
Publikováno v:
Mol Ther
Calvarial bone healing is challenging, especially for individuals with osteoporosis because stem cells from osteoporotic patients are highly prone to adipogenic differentiation. Based on previous findings that chondrogenic induction of adipose-derive
Publikováno v:
Genomics. 114:215-228
The study of gene expression variability, especially for cancer and cell differentiation studies, has become important. Here, we investigate transcriptome-wide scatter of 23 cell types and conditions across different levels of biological-complexity.
Autor:
David T. Breault, Wanshu Qi, Jose Ordovas-Montanes, Sarah Dubois, Diana L. Carlone, Manasvi S. Shah, Daniel Zeve, Joshua de Sousa Casal, Sophie Hafner, Eric Stas, Jeffrey M. Karp, Xiaolei Yin, Erin Syverson, Prabhath Mannam
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Nature Communications
Nature Communications
Enteroendocrine (EE) cells are the most abundant hormone-producing cells in humans and are critical regulators of energy homeostasis and gastrointestinal function. Challenges in converting human intestinal stem cells (ISCs) into functional EE cells,
Autor:
Tessa Werner, Quan Nguyen, Stephen T. Bradford, Enakshi Sinniah, Zhixuan Wu, Sean B. Wilson, James E. Hudson, Woo Jun Shim, Joseph E. Powell, Maika Matsumoto, Nathan J. Palpant, Yuliangzi Sun, Sophie Shen, Melissa H. Little
Publikováno v:
Trends in Molecular Medicine. 27:1135-1158
Pluripotent stem cells underpin a growing sector that leverages their differentiation potential for research, industry, and clinical applications. This review evaluates the landscape of methods in single-cell transcriptomics that are enabling acceler