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pro vyhledávání: '"Saad Alobid"'
Autor:
Thiagarajan Venkatesan, Saad Alobid, Mohammad Algahtani, Thanigaivelan Kanagasabai, Appu Rathinavelu, Khalid Alhazzani, Umamaheswari Natarajan
Publikováno v:
Cellular Signalling. 66:109435
Overexpression of MDM2 oncoprotein has been detected in a large number of diverse human malignancies and has been shown to play both p53-dependent and p53-independent roles in oncogenesis. Our study was designed to explore the impact of MDM2 overexpr
Autor:
Ali Alaseem, Thiagarajan Venkatesan, Saad Alobid, Priya Dondapati, Khalid Alhazzani, Appu Rathinavelu
Publikováno v:
Cancer Research. 76:1839-1839
MDM2 gene is a cellular proto-oncogene amplified in 25-40% of all human cancers and regulates cell proliferation, senescence, and apoptosis through targeting p53. It is widely speculated that MDM2 protein is not only responsible for tumorigenesis via