Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Deok-Ho Kim"'
Autor:
Corrado Poggesi, Chiara Tesi, Alice Ward Racca, Michael R. Hoopmann, Cecilia Ferrantini, J. Manuel Pioner, Lil Pabon, Jordan M. Klaiman, Veronica Muskheli, Michael Regnier, Xuan Guan, Martin K. Childers, Deok Ho Kim, David L. Mack, Charles E. Murry, Robert L. Moritz, Jesse Macadangdang
Publikováno v:
Cardiovasc Res
Aims Heart failure invariably affects patients with various forms of muscular dystrophy (MD), but the onset and molecular sequelae of altered structure and function resulting from full-length dystrophin (Dp427) deficiency in MD heart tissue are poorl
Autor:
Jayhyun Seo, Andrew J. Ewald, Andre Levchenko, Chia Yi Su, Moon Kyu Kwak, JinSeok Park, Deok Ho Kim, Ryan S. Gray, Kshitiz, Steven S. An
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
The root cause of cancer mortality and morbidity is the metastatic spread of the primary tumor, but underlying mechanisms remain elusive. Here we investigate biomechanical interactions that may accompany invasive spread of melanoma cells. We find tha
Publikováno v:
Circulation Research. 127
Background: Human induced pluripotent stem cells (hiPSCs) are widely used in studies of developmental and regenerative biomedicine involving various cell types, including cardiomyocytes (CMs). Understanding the cellular and molecular processes during
Publikováno v:
American Journal of Physiology: Lung Cellular & Molecular Physiology; Dec2021, Vol. 321 Issue 6, pL1072-L1088, 17p
Autor:
Deok Ho Kim, JinSeok Park, Andre Levchenko, Hong Nam Kim, Steven S. An, Eun Mi Hur, Moon Kyu Kwak, Chiaochun Joanne Wang, Kahp-Yang Suh
Publikováno v:
Nature materials
Living cells and the extracellular matrix (ECM) can display complex interactions that define key developmental, physiological and pathological processes. Here, we report a new type of directed migration — which we term ‘topotaxis’ — by which
Publikováno v:
Progress in polymer science. 65
Human tissues are sophisticated ensembles of many distinct cell types embedded in the complex, but well-defined, structures of the extracellular matrix (ECM). Dynamic biochemical, physicochemical, and mechano-structural changes in the ECM define and
Autor:
Yeonju Kim, Chong-Su Cho, Deok Ho Kim, Jong Hoon Chung, Jangho Kim, Hoon Seonwoo, Ki Tack Lim, Kyoung Soon Choi, Pill Hoon Choung, Yun-Hoon Choung, Soo Young Kim, Yensil Park
Publikováno v:
Journal of Biomedical Materials Research Part A. 101:3520-3530
Nanoscale topography of artificial substrates can greatly influence the fate of stem cells including adhesion, proliferation, and differentiation. Thus the design and manipulation of nanoscale stem cell culture platforms or scaffolds are of great imp
Autor:
Kai Chun Yang, Rebecca J. Zaunbrecher, Chiara Tesi, Mark Y. Jeong, Deok Ho Kim, Josè Manuel Pioner, Jordan M. Klaiman, Alice Ward Racca, David L. Mack, Charles E. Murry, Martin K. Childers, Lil Pabon, Corrado Poggesi, Michael Regnier, Veronica Muskheli, Xuan Guan, Jesse Macadangdang
Publikováno v:
Stem Cell Reports, Vol 6, Iss 6, Pp 885-896 (2016)
Stem Cell Reports
Stem Cell Reports
Summary Tension production and contractile properties are poorly characterized aspects of excitation-contraction coupling of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). Previous approaches have been limited due to the smal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be627a85caeb998014f5f9c5d9625d11
http://hdl.handle.net/2158/1048856
http://hdl.handle.net/2158/1048856
Publikováno v:
Integrative Biology. 4:1008-1018
The phenotypic expression and function of stem cells are regulated by their integrated response to variable microenvironmental cues, including growth factors and cytokines, matrix-mediated signals, and cell–cell interactions. Recently, growing evid
Autor:
Veronica Muskheli, Christian I. Childers, Xuan Guan, Corrado Poggesi, Lil Pabon, Alice Ward Racca, Charles E. Murry, David L. Mack, Michael Regnier, Jesse Macadangdang, Mark Y. Jeong, Deok Ho Kim, Josè Manuel Pioner, Martin K. Childers
Publikováno v:
Biophysical Journal. 108(2)
Duchenne Muscular Dystrophy (DMD) is a wasting disease of striated muscle resulting from membrane fragility. We modeled DMD cardiac disease using urine-derived cells from a patient, reprogrammed to induced pluripotent stem cells (hiPSCs) and differen