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pro vyhledávání: '"Yasuo Urata"'
Autor:
Kanae Abe, Yasuo Urata, Natsuki Yanase, Hiroyuki Mizuguchi, Akikazu Asada, Hideki Hayakawa, Fuminori Sakurai
Publikováno v:
Biologicalpharmaceutical bulletin. 41(10)
In recent times, oncolytic viruses expressing an extraneous gene have attracted great interest; in fact, they have been engaged in multiple applications, such as medicine for cancer. Our group made an oncolytic adenovirus, namely, OBP-301, for use in
Publikováno v:
Current cancer drug targets. 7(2)
Replication-selective tumor-specific viruses present a novel approach for treatment of neoplastic disease. These vectors are designed to induce virus-mediated lysis of tumor cells after selective viral propagation within the tumor. For targeting canc
Autor:
Yuuri Hashimoto, Toshiyoshi Fujiwara, Katsuyuki Nagai, Fuminori Teraishi, Yuichi Watanabe, Shunsuke Kagawa, Noriaki Tanaka, Hitoshi Kawamura, Yasuo Urata
Publikováno v:
Molecular Therapy. 13:S56
Background: We previously reported that an attenuated adenovirus (OBP-301, 'Telomelysin'), in which the hTERT promoter element drives expression of E1A and E1B genes linked with an IRES, could replicate in cancer cells, and causes selective lysis of