Zobrazeno 21 - 30
of 57
pro vyhledávání: '"Ye Zheng"'
Autor:
Mathias Leblanc, Christopher Liddle, Ronald M. Evans, Annette R. Atkins, Ruth T. Yu, Jae Myoung Suh, Yuqiong Liang, Ye Zheng, Michael Downes, Sihao Liu, Carmen Zhou, Sungsoon Fang, Yang Zhang, Albert Cheng, Sagar P. Bapat
Publikováno v:
Nature. 528:137-141
Age-associated insulin resistance (IR) and obesity-associated IR are two physiologically distinct forms of adult-onset diabetes. While macrophage-driven inflammation is a core driver of obesity-associated IR, the underlying mechanisms of the obesity-
Autor:
Soyoung Ha, Dan R. Littman, Brandon N. Nelson, Jingping Lu, Saiyu Hang, Michael A. Fischbach, Jamma Trinath, Michael R. Krout, Donggi Paik, Ye Zheng, Samantha P. Kelly, Lin Wu, Fraydoon Rastinejad, A. Sloan Devlin, Jun R. Huh
Publikováno v:
The Journal of Immunology. 204:230.6-230.6
Bile acids are abundantly present in the mammalian gut, where they undergo bacteria-mediated transformation, generating a large pool of bioactive molecules. While they have been shown to affect host metabolism, cancer progression and innate immunity,
Autor:
Yun Zhou, Jing Zhang, Charu Mehta, Kirby D. Johnson, Inga Hofmann, Jun Wu, Sunduz Keles, Kyunghee Choi, Alexandra A. Soukup, Peng Liu, Emery H. Bresnick, Miao Cao, Ye Zheng
Publikováno v:
The Journal of clinical investigation. 129(3)
The development and function of stem and progenitor cells that produce blood cells are vital in physiology. GATA-binding protein 2 (GATA2) mutations cause GATA-2 deficiency syndrome involving immunodeficiency, myelodysplastic syndrome, and acute myel
Autor:
Ruiqi Liao, Emery H. Bresnick, Yuannyu Zhang, Jian Xu, Joshua J. Coon, Nobuyuki Tanimura, Matthew R. Dent, Peiman Hematti, Gary M. Wilson, Ye Zheng, Xin Liu, Miao Cao, Judith N. Burstyn, Sunduz Keles
Publikováno v:
Developmental cell. 46(5)
By functioning as an enzyme cofactor, hemoglobin component, and gene regulator, heme is vital for life. One mode of heme-regulated transcription involves amplifying the activity of GATA-1, a key determinant of erythrocyte differentiation. To discover
Autor:
Jailal N. G. Ablack, Mark H. Ginsberg, Jack D. Bui, Kelly A. Remedios, John T. Chang, Patrick J. Metz, Li-Fan Lu, Joseph M. Cantor, Jane E. Klann, Zhaoren He, Jocelyn G. Olvera, Stephanie H. Kim, Justine Lopez, Brian G. Petrich, Tiffani Tysl, Gene W. Yeo, Ye Zheng, Brigid S. Boland
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 200(12)
Maintenance of the regulatory T (Treg) cell pool is essential for peripheral tolerance and prevention of autoimmunity. Integrins, heterodimeric transmembrane proteins consisting of α and β subunits that mediate cell-to-cell and cell-to-extracellula
Autor:
Jovan Shepherd, Yi Liu, Ye Zheng, Christian J. Maine, Guo Fu, Mohsen Sabouri-Ghomi, Changchun Xiao, Nengming Xiao, Seung Goo Kang, Cheng-Jang Wu, Shunbin Xu, Alicia Gonzalez-Martin, Li-Fan Lu, Zhe Huang, Wen Hsien Liu, Alexander Hoffmann, Hyun Yong Jin
Publikováno v:
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
The Journal of Experimental Medicine
The Journal of experimental medicine, vol 213, iss 9
instname
The Journal of Experimental Medicine
The Journal of experimental medicine, vol 213, iss 9
Xiao and collaborators show that miR-155 regulates T follicular helper cell development and function by suppressing the E3 ubiquitin ligase Peli1.
MicroRNA (miRNA) deficiency impairs the generation of T follicular helper (Tfh) cells, but the con
MicroRNA (miRNA) deficiency impairs the generation of T follicular helper (Tfh) cells, but the con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aa5ed3a272de3dc5bb9fdbe6d6cbcd4
http://hdl.handle.net/10486/685850
http://hdl.handle.net/10486/685850
Autor:
Ronald M. Evans, Annette R. Atkins, Ye Zheng, Michael Downes, Weiwei Fan, Christopher Liddle, Ruth T. Yu, Nanhai He, Brian Henriquez
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Regulatory T cells (Tregs) play a critical role in maintaining immune tolerance to self-antigens and in suppressing excessive immune responses that may cause collateral damage to the host. Unlike other CD4+ T cells, Tregs have a distinct
Autor:
Lauren A. Mack, Christopher Liddle, Sigal Gery, Zhengshan Chen, Qi Cao, Henry Yang, Xianping Shi, Xuan Zhao, Haibo Sun, De-Chen Lin, Qi Chen, Jonathan W. Said, Serhan Alkan, Jing-Wen Bai, Ruishu Deng, Ling Wa Chong, Markus Müschen, Michael Downes, Ronald M. Evans, Jian-Jun Xie, Han Cho, Ruth T. Yu, Annette R. Atkins, Ye Zheng, Quan Zhen Li, H. Phillip Koeffler
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 114, iss 47
The circadian system regulates numerous physiological processes including immune responses. Here, we show that mice deficient of the circadian clock genes Cry1 and Cry2 [Cry double knockout (DKO)] develop an autoimmune phenotype including high serum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec83e67eefb01b297a9051e42544974f
https://escholarship.org/uc/item/6wn972xv
https://escholarship.org/uc/item/6wn972xv
Autor:
Johan Auwerx, Ying Cui, Ruth T. Yu, Ronald M. Evans, Jianrong Wang, Hui Xiao, Caroline Zhang, Shuo Zhang, Annette R. Atkins, Ye Zheng, Na Zhang, Ruihong Zhu, Nanhai He, Michael Downes, Dexian Quan, Christopher Liddle, Qibin Leng, Chunhui Yang
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Nature Communications
Nature Communications
Thymocytes must pass both positive and negative selections to become mature T cells. Negative selection purges thymocytes whose T-cell receptors (TCR) exhibit high affinity to self-peptide MHC complexes (self pMHC) to avoid autoimmune diseases, while
Publikováno v:
Frontiers in Plant Science, Vol 7 (2016)
Low temperature affects gene regulatory networks and alters cellular metabolism to inhibit plant growth. Peroxidases are widely distributed in plants and play a large role in adjusting and controlling reactive oxygen species (ROS) homeostasis in resp