Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Wayne Tam"'
Autor:
Maher Albitar, Hong Zhang, Andre Goy, Zijun Y. Xu-Monette, Govind Bhagat, Carlo Visco, Alexandar Tzankov, Xiaosheng Fang, Feng Zhu, Karen Dybkaer, April Chiu, Wayne Tam, Youli Zu, Eric D. Hsi, Fredrick B. Hagemeister, Jooryung Huh, Maurilio Ponzoni, Andrés J. M. Ferreri, Michael B. Møller, Benjamin M. Parsons, J. Han van Krieken, Miguel A. Piris, Jane N. Winter, Yong Li, Bing Xu, Ken H. Young
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 2, Pp 1-9 (2022)
Blood Cancer Journal, 12
Blood Cancer Journal, 12, 2
Albitar, M, Zhang, H, Goy, A, Xu-Monette, Z Y, Bhagat, G, Visco, C, Tzankov, A, Fang, X, Zhu, F, Dybkaer, K, Chiu, A, Tam, W, Zu, Y, Hsi, E D, Hagemeister, F B, Huh, J, Ponzoni, M, Ferreri, A J M, Møller, M B, Parsons, B M, van Krieken, J H, Piris, M A, Winter, J N, Li, Y, Xu, B & Young, K H 2022, ' Determining clinical course of diffuse large B-cell lymphoma using targeted transcriptome and machine learning algorithms ', Blood Cancer Journal, vol. 12, no. 2, 25 . https://doi.org/10.1038/s41408-022-00617-5
Albitar, M, Zhang, H, Goy, A H, Xu-Monette, Z, Bhagat, G, Visco, C, Tzankov, A, Fang, X, Zhu, F, Dybkaer, K, Chiu, A, Tam, W, Zu, Y, Hsi, E D, Hagemeister, F B, Huh, J, Ponzoni, M, Ferreri, A J M, Moller, M, Parsons, B M, Van Krieken, J H J M, Piris, M A, Winter, J N, Li, Y, Xu, B & Young, K H 2021, ' Determining Clinical Course of Diffuse Large B-Cell Lymphoma Using Targeted Transcriptome and Machine Learning Algorithms ', Blood, vol. 138, no. Suppl. 1, 2395 . https://doi.org/10.1182/blood-2021-148841
Blood Cancer Journal
Blood Cancer Journal, 12
Blood Cancer Journal, 12, 2
Albitar, M, Zhang, H, Goy, A, Xu-Monette, Z Y, Bhagat, G, Visco, C, Tzankov, A, Fang, X, Zhu, F, Dybkaer, K, Chiu, A, Tam, W, Zu, Y, Hsi, E D, Hagemeister, F B, Huh, J, Ponzoni, M, Ferreri, A J M, Møller, M B, Parsons, B M, van Krieken, J H, Piris, M A, Winter, J N, Li, Y, Xu, B & Young, K H 2022, ' Determining clinical course of diffuse large B-cell lymphoma using targeted transcriptome and machine learning algorithms ', Blood Cancer Journal, vol. 12, no. 2, 25 . https://doi.org/10.1038/s41408-022-00617-5
Albitar, M, Zhang, H, Goy, A H, Xu-Monette, Z, Bhagat, G, Visco, C, Tzankov, A, Fang, X, Zhu, F, Dybkaer, K, Chiu, A, Tam, W, Zu, Y, Hsi, E D, Hagemeister, F B, Huh, J, Ponzoni, M, Ferreri, A J M, Moller, M, Parsons, B M, Van Krieken, J H J M, Piris, M A, Winter, J N, Li, Y, Xu, B & Young, K H 2021, ' Determining Clinical Course of Diffuse Large B-Cell Lymphoma Using Targeted Transcriptome and Machine Learning Algorithms ', Blood, vol. 138, no. Suppl. 1, 2395 . https://doi.org/10.1182/blood-2021-148841
Blood Cancer Journal
Introduction: Multiple studies have demonstrated that diffuse large B-cell lymphoma (DLBCL) can be divided into subgroups based on their biology. However, these biological subgroups overlap clinically. While R-CHOP (rituximab, cyclophosphamide, doxor
Autor:
Luca Vincenzo Cappelli, Danilo Fiore, Jude M. Phillip, Liron Yoffe, Filomena Di Giacomo, William Chiu, Yang Hu, Clarisse Kayembe, Michael Ginsberg, Lorena Consolino, Jose Gabriel Barcia Duran, Nahuel Zamponi, Ari M. Melnick, Francesco Boccalatte, Wayne Tam, Olivier Elemento, Sabina Chiaretti, Anna Guarini, Robin Foà, Leandro Cerchietti, Shahin Rafii, Giorgio Inghirami
Publikováno v:
Blood.
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive and often incurable disease. To uncover therapeutic vulnerabilities, we first developed T-ALL patient–derived tumor xenografts (PDXs) and exposed PDX cells to a library of 433 clinical-st
Autor:
Dylan McNally, Andrew Lytle, Hiranmayi Ravichandran, Wayne Tam, Christian Steidl, David W. Scott, Ari Melnick, Olivier Elemento
Publikováno v:
Blood. 140:162-163
Autor:
Weiqing Wei, Shuhua Cheng, Jingqi Zhou, Zijing Peng, Jiao Ma, Wenhan Wang, Yizhuo Ren, Kristy L. Richards, Kui Nie, Wayne Tam, Yitao Qi, Yajie Shen, Daiji Jiang, Jinke Cheng, Yirong Zhang, Zhengming Chen, Qiuju Fan
Publikováno v:
Blood. 139(1)
Although oncogenicity of the stem cell regulator SOX9 has been implicated in many solid tumors, its role in lymphomagenesis remains largely unknown. In this study, SOX9 was overexpressed preferentially in a subset of diffuse large B-cell lymphomas (D
Autor:
Leandro Cerchietti, Jia Ruan, David M. Hyman, Sonali M. Smith, Morton Coleman, Amelyn Rodriguez, Paul J. Christos, Stephen J. Schuster, Bijal D. Shah, John P. Leonard, Wayne Tam, Peter Martin, Maria Nieves Calvo-Vidal, Jakub Svoboda, Richard R. Furman
Publikováno v:
Blood. 132:2016-2025
We report 5-year follow-up of a multicenter phase 2 study of lenalidomide plus rituximab (LR) as initial treatment of mantle cell lymphoma (MCL). The regimen includes induction and maintenance with the LR doublet. Treatment was continuous until progr
Autor:
Chao Wang, Stephen Hamilton-Dutoit, Michael Boe Møller, Weiwei Zhang, Francesco d'Amore, Trine Lindhardt Plesner, Marcus Celik Hansen, Maja Ludvigsen, Wing C. Chan, Danilo Fiore, Giorgio Inghirami, Peter Noergaard, Bo Kok Mortensen, Martin Bjerregaard Pedersen, Wayne Tam, Henrik Frederiksen, Johanne Marie Holst
Publikováno v:
Holst, J M, Pedersen, M B, Hansen, M C, Lindhardt Plesner, T, Frederiksen, H, Møller, M B, Hamilton-Dutoit, S J, Nørgaard, P, Mortensen, B K, Fiore, D, Wang, C, Wang, C, Tam, W, Ludvigsen, M, Chan, W C, Inghirami, G & d'Amore, F A 2019, ' Shared Genomic Alterations in Patients with Co-Existing Myeloproliferative Neoplasms and Angioimmunoblastic T-Cell Lymphoma ', Blood, vol. 134, no. Supplement 1, 2776 . https://doi.org/10.1182/blood-2019-131465
University of Southern Denmark
Holst, J M, Pedersen, M B, Hansen, M C, Lindhardt Plesner, T, Frederiksen, H, Møller, M, Hamilton-Dutoit, S J, Nørgaard, P, Mortensen, B K, Fiore, D, Wang, C, Wang, C, Tam, W, Ludvigsen, M, Chan, W C, Inghirami, G & d'Amore, F A 2019, ' Shared Genomic Alterations in Patients with Co-Existing Myeloproliferative Neoplasms and Angioimmunoblastic T-Cell Lymphoma ', American Society of Hematology: 61st Annual Meeting (ASH), Orlando, United States, 07/12/2019-10/12/2019 . < https://ash.confex.com/ash/2019/webprogram/Paper131465.html >
University of Southern Denmark
Holst, J M, Pedersen, M B, Hansen, M C, Lindhardt Plesner, T, Frederiksen, H, Møller, M, Hamilton-Dutoit, S J, Nørgaard, P, Mortensen, B K, Fiore, D, Wang, C, Wang, C, Tam, W, Ludvigsen, M, Chan, W C, Inghirami, G & d'Amore, F A 2019, ' Shared Genomic Alterations in Patients with Co-Existing Myeloproliferative Neoplasms and Angioimmunoblastic T-Cell Lymphoma ', American Society of Hematology: 61st Annual Meeting (ASH), Orlando, United States, 07/12/2019-10/12/2019 . < https://ash.confex.com/ash/2019/webprogram/Paper131465.html >
Background: Myeloproliferative neoplasia (MPN) and angioimmunoblastic T-cell lymphoma (AITL) are two distinct hematologic cancers. However, we have shown that patients with both malignancies probably occur with frequencies higher than expected in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b030c4e0750ddf7e034f1d70f9f834f
https://portal.findresearcher.sdu.dk/da/publications/3b5d4d69-5905-42b7-b2b5-0b29f1976d95
https://portal.findresearcher.sdu.dk/da/publications/3b5d4d69-5905-42b7-b2b5-0b29f1976d95
Autor:
Jesus G. Berdeja, Ronan T. Swords, Farhad Sedarati, Michael R. Savona, Iwona Pawlikowska-Dobler, Bruce J. Dezube, Ajeeta B Dash, Joshua F. Zeidner, Douglas V. Faller, Steven Coutre, Jose C. Cruz, James M. Foran, Hélène M. Faessel, Saran Vardhanabhuti, Wayne Tam, Harry P. Erba, Michael B. Maris
Publikováno v:
Blood. 131:1415-1424
Pevonedistat (TAK-924/MLN4924) is a novel inhibitor of NEDD8-activating enzyme (NAE) with single-agent activity in relapsed/refractory acute myeloid leukemia (AML). We performed a phase 1b study of pevonedistat (PEV) with azacitidine (AZA) based on s
Autor:
Lorena Consolino, Leandro Cerchietti, Sabina Chiaretti, Shahin Rafii, Francesco Boccalatte, Robin Foà, Yang Hu, Luca Vincenzo Cappelli, Filomena Di Giacomo, Michael Ginsberg, Olivier Elemento, Ari Melnick, Liron Yoffe, Wayne Tam, Danilo Fiore, Giorgio Inghirami, Nahuel Zamponi, Clarisse Kayembe, Jude M. Phillip, José Gabriel Barcia Durán, Anna Guarini
Publikováno v:
Blood. 138:704-704
Background. T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive disease with few innovative treatment options. This is also contributed by the lack of models capable of capturing the complexity of the tumor and its microenvironment. Aims. To
Autor:
Luca Vincenzo Cappelli, Giuseppina Astone, Giorgio Inghirami, Wayne Tam, William Chiu, Maria Teresa Cacciapuoti, Giorgia Zanetti, Joseph M. Scandura, Lisa Giulino Roth, Danilo Fiore, Clarisse Kayembe, Lorenzo Galluzzi, Silvana Di Giandomenico
Publikováno v:
Blood. 138:2406-2406
Introduction: Immunotherapy is a promising therapeutic intervention for cancer treatment. Activation of the immune system via checkpoint blockade has been shown to produce antitumor responses in patients with both solid and hematological tumors. Howe
Autor:
Giorgio Inghirami, Jiao Ma, Kenneth Eng, Mina L. Xu, Kui Nie, Jerald Z. Gong, Yajie Shen, Rex Au-Yeung, Olivier Elemento, Gopesh Srivastava, Leonard Tan, Wayne Tam
Publikováno v:
Blood. 134:2770-2770
INTRODUCTION : Diffuse large B cell lymphoma (DLBCL) is a malignant non-Hodgkin's lymphoma with approximately one third of patients respond to front-line treatment such as R-CHOP. However, most of the patients often relapse within 2-3 years, and thei