Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Stefania Lenna"'
Autor:
Stefania Lenna, Ava Brozovich, Takashi Hirase, Francesca Paradiso, Bradley K. Weiner, Francesca Taraballi
Publikováno v:
Stem Cells and Development. 31:672-683
Due to their immunosuppressive potential and ability to differentiate into multiple musculoskeletal cell lineages, mesenchymal stromal cells (MSCs) became popular in clinical trials for the treatment of musculoskeletal disorders. The aim of this stud
Autor:
Lewis Francis, Marcos Quintela, R.S. Conlan, Francesca Taraballi, Francesca Paradiso, David James, Sergio Caserta, Stefano Serpelloni, Stefania Lenna
Publikováno v:
SSRN Electronic Journal.
The complexity of studying a neoplastic disease relies on understanding specialized cell types within the tumor tissue, which can be recruited and ‘corrupted’ to create a dynamic pro-tumorigenic network called the ‘tumor microenvironment’ (TM
Publikováno v:
IUBMB Life. 66:530-537
Prolonged perturbation of the endoplasmic reticulum (ER) leads to ER stress and unfolded protein response (UPR) and contributes to the pathogenesis of various chronic disorders. This review focuses on the role of ER stress and UPR in endothelial cell
Publikováno v:
Journal of Cellular Physiology. 228:1774-1783
Systemic sclerosis (SSc) is a complex disease characterized by vascular alterations, activation of the immune system and tissue fibrosis. Previous studies have implicated activation of the interferon pathways in the pathogenesis of SSc. The goal of t
Publikováno v:
Journal of Dermatological Science. 67:166-172
Scleroderma (SSc) is characterized by excess production and deposition of extracellular matrix (ECM) proteins. Activated fibroblasts play a key role in fibrosis in SSc and are resistant to Fas-mediated apoptosis. Acid sphingomyelinase (ASMase), a maj
Autor:
Elke Hacker, Juxiang Cao, Nicholas K. Hayward, Celia Jiménez-Cervantes, Wenyi Wei, Hans R. Widlund, Rutao Cui, George X. Xu, Colin R. Goding, Yongjun Wang, Rhoda M. Alani, Nick R. Leslie, Lixin Wan, Ken Dutton-Regester, Byungwoo Ryu, Stefania Lenna, Xiangpeng Dai
Publikováno v:
Molecular cell. 51(4)
The individuals carrying melanocortin-1 receptor (MC1R) variants, especially those associated with red hair color, fair skin, and poor tanning ability (RHC trait), are more prone to melanoma; however, the underlying mechanism is poorly defined. Here,
Autor:
Maria Trojanowska, Stefania Lenna
To review the present knowledge of the role of endoplasmic reticulum (ER) stress and unfolded protein response (UPR) in the pathogenesis of fibrotic diseases.ER stress and UPR occur in a number of diseases associated with organ fibrosis; however, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecfb5dd7660a1290353ffa30c23dd6b4
https://europepmc.org/articles/PMC3828639/
https://europepmc.org/articles/PMC3828639/
Autor:
Danyelle M. Townsend, Filemon K. Tan, Raffaella Scorza, Bagrat Kapanadze, Maria Trojanowska, Malgorzata Markiewicz, Stefania Lenna
Publikováno v:
J Immunol
The presence of the HLA-B35 allele has emerged as an important risk factor for the development of isolated pulmonary hypertension in patients with scleroderma, however the mechanisms underlying this association have not been fully elucidated. The goa
Autor:
George X. Xu, S. Jimenez-Cervantes, J. Shen, Nick R. Leslie, Rutao Cui, Yongjun Wang, Juxiang Cao, Stefania Lenna, F. Liu
Publikováno v:
Journal of Investigative Dermatology. :S123-S134