Zobrazeno 1 - 10
of 253
pro vyhledávání: '"Sheela, A."'
Autor:
Tea Soon Park, Rishabh Hirday, Russell Quinn, Sheela Panicker Jacob, Ricardo A. Feldman, Devika Bose, Ruchi Sharma, Kapil Bharti
Publikováno v:
STAR Protocols, Vol 5, Iss 1, Pp 102827- (2024)
Summary: Here, we present a protocol to differentiate induced pluripotent stem cell (iPSC) into adherent hematopoietic progenitors that release floating CD14+ CD45+ monocytes into the culture medium. We describe steps for iPSC expansion, embryoid bod
Externí odkaz:
https://doaj.org/article/47b0693c0a584adc9446cc892a7a2ebf
Autor:
Anil Kumar, Sung June Lee, Qiao Liu, Anthony K.N. Chan, Sheela Pangeni Pokharel, Jianhua Yu, Chun-Wei Chen, Srividya Swaminathan
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100874- (2021)
Summary: Cytotoxic natural killer cells kill tumors and infected cells. We carried out CRISPR-based gene editing and transcriptional regulation in hard-to-manipulate NK-92 cells. NK-92-based therapies were found to be safe and efficacious in preclini
Externí odkaz:
https://doaj.org/article/576f760e90424b94b161b522d97bd3a9
Autor:
Yamuna Devi Bakthavatchalam, Divyaa Elangovan, Subha Vajjiravelu Jaganathan, Nivedhana Subburaju, Abirami Shankar, Yuvasri Manokaran, Sudarsana J., Rema Devi, Sujata Baveja, Sheela Devi, Jayakumar S., Sanjay Bhattacharya, Rudresh S. M., Bineshlal Yesudhason, Vignesh Shetty, Ankur Mutreja, Abi Manesh, George M. Varghese, Charis A. Marwick, Benjamin J. Parcell, Ian H. Gilbert, Balaji Veeraraghavan
Publikováno v:
Microbiology Spectrum. 11
The study revealed the differential ability of cefepime/taniborbactam and cefepime/zidebactam in tackling carbapenemase-producing Indian clinical isolates that also harbored additional mechanisms of resistance. NDM-expressing E. coli with 4-amino-aci
Publikováno v:
Experimental Hematology. :7-15
Highlights: Extracellular vesicles (EVs) are small lipid bilayer particles containing biologically important cargo and impart regulatory changes in target cells. Despite the importance of EVs in cellular communication, there remains a gap in our unde
Autor:
Tohru Fukai, David Fulton, Sheela Nagarkoti, Masuko Ushio-Fukai, Dipankar Ash, Eric J. Belin de Chantemèle
Publikováno v:
Antioxid Redox Signal
Reactive oxygen species (ROS; e.g., superoxide [O(2)(•−)] and hydrogen peroxide [H(2)O(2)]) and reactive nitrogen species (RNS; e.g., nitric oxide [NO(•)]) at the physiological level function as signaling molecules that mediate many biological
Autor:
Debasish Kumar Ghosh, Shruti Pande, Jeevan Kumar, Dhanya Yesodharan, Sheela Nampoothiri, Periyasamy Radhakrishnan, Chilakala Gangi Reddy, Akash Ranjan, Katta M. Girisha
Publikováno v:
Aging cell. 21(11)
Deleterious, mostly de novo, mutations in the lamin A (LMNA) gene cause spatio-functional nuclear abnormalities that result in several laminopathy-associated progeroid conditions. In this study, exome sequencing in a sixteen-year-old male with manife
Autor:
Sreelekha Therakathinal Thankappan Nair, Unnikrishnan Babukuttan Sheela, Sreekutty Jalajakumari, Anuj Tripathi, Catherine C. Berry, Preethi Gopalakrishnan Usha, Deepa Mohan
Publikováno v:
Journal of Biomaterials Applications. 36:541-551
Hydrogels are reported to have various biomedical field applications, and many reports also suggest that soft gels promote stem cell differentiation. Chondrogenic differentiation of mesenchymal stem cells (MSC) is significant in articular cartilage r
Publikováno v:
International Journal of Anatomy and Research. 9:7948-7954
Background: Placenta forms an intimate bonding between the mother and the foetus. Apart from gaseous exchange, transport of nutrients from mother to the foetus, any disease or disorder affecting the mother also reflects the foetus. Hypertension durin
Publikováno v:
International Journal of Anatomy and Research. 9:7942-7947
Background: Rectus sternalis is considered as an unusual accessory or supernumerary muscle which appears either unilateral or bilateral in the anterior thoracic wall of human beings. It varies in length, breadth, thickness and incidence among differe
Autor:
Sheela Ramanathan, Madanraj Appiya Santharam, Maryse Cloutier, Awais Ullah Ihsan, Akhil Shukla, Dominique Lévesque, François-Michel Boisvert, Subburaj Ilangumaran
Publikováno v:
Biochimie. 182:185-196
Suppressor of Cytokine Signaling 1 (SOCS1) functions as a tumor suppressor in hepatocellular carcinoma and many other types of cancers. SOCS1 mediates its functions by inhibiting tyrosine kinases, promoting ubiquitination and proteasomal degradation