Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ruizhen Sun"'
Publikováno v:
Reproduction. 164:221-230
In brief Several factors affect the reprogramming efficiency of nuclear transfer embryos. This study shows that inhibiting 18S rRNA m6A methyltransferase METTL5 during nuclear transfer can improve the developmental rate of nuclear transfer embryos. A
Autor:
Ruizhen Sun, Tiantian Gong, Hui Liu, Jingling Shen, Bin Wu, Qi Jiang, Qi Wang, Yue Zhang, Lian Duan, Jing Hu, Qiuming Li, Lei Lei, Zhiyan Shan
Publikováno v:
Journal of Molecular Histology. 53:623-634
Differentiated cells can be reprogrammed to embryonic stem cell-like cells called induced pluripotent stem cells (iPSCs), in which the natural developmental differentiation process is reversed. It is unclear whether the multi-lineage cells can be iso
Autor:
Jingling Shen, Zhiyan Shan, Feng Liu, Lei Lei, Ruizhen Sun, Xing-Hui Shen, Xinglin Hu, Hui Liu, Zhaojun Liu, Meng Gao
Publikováno v:
Cellular Reprogramming. 22:90-98
Induced pluripotent stem cell (iPSC) technology refers to the reprogramming of terminally differentiated somatic cells into pluripotent stem cells by introducing specific transcription factors that are known to regulate pluripotency, including Oct4,
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2018 (2018)
BioMed Research International, Vol 2018 (2018)
Foam cell formation and macrophage polarization are involved in the pathologic development of atherosclerosis, one of the most important human diseases affecting large and medium artery walls. This study was designed to assess the effects of rapamyci
Autor:
Yukuan Feng, Ruizhen Sun, Jing Hu, Qiaoshi Zhao, Yanshuang Wu, Zhiyan Shan, Lei Lei, Yanli Gu, Lian Duan, Na Li
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Scientific Reports
Scientific Reports
Patient-specific induced pluripotent stem cells (iPSCs) have the potential to be useful in the treatment of human diseases. While prior studies have reported multiple methods to generate iPSCs, DNA methylation continues to limit the totipotency and r
Publikováno v:
Zygote. 26:24-32
SummarySomatic cell nuclear transfer (SCNT) is an important technique for life science research. However, most SCNT embryos fail to develop to term due to undefined reprogramming defects. Here, we show that abnormal Xi occurs in somatic cell NT blast
Autor:
Chun-Jia Liu, Ruizhen Sun, Zhiyan Shan, Zhen-Dong Wang, Guang-Yu Bai, Lei Lei, Si-Hang Song, Yanshuang Wu, Tong Li
Publikováno v:
Development, Growth & Differentiation. 58:270-279
Mouse parthenogenetic embryonic stem cells (PgESCs) could be applied to study imprinting genes and are used in cell therapy. Our previous study found that stem cells established by aggregation of two parthenogenetic embryos at 8-cell stage (named as
Autor:
Gerelchimeg Bou, Ruizhen Sun, Binghua Xue, Renyue Wei, Shichao Liu, Zhonghua Liu, Austin J. Cooney, Shimeng Guo
Publikováno v:
Developmental Dynamics. 244:619-627
Background: Mammalian first lineage segregation generates trophectoderm (TE) and pluripotent inner cell mass (ICM), which provides an ideal model for studying the mechanisms of maintenance and loss of pluripotency. In mouse, the transcription factor
Autor:
Kui Hu, Zhonghua Liu, Shichao Liu, Jingling Shen, Jiaqiang Wang, Ruizhen Sun, Lian Duan, Jianyu Wang, Yanli Gu, Binghua Xue, Lei Lei, Lianhong Jin, Yimei Cong, Xing-Hui Shen
Publikováno v:
Zygote. 23:266-276
SummaryMorphogenesis and identification of embryonic differentiation in porcine embryos are crucial issues for developmental biology and laboratory animal science. The current paper presents a study on the asynchronous development of hatched porcine
Autor:
Zhonghua Liu, Jiaqiang Wang, Jianyu Wang, Ruizhen Sun, Kui Hu, Yimei Cong, Juan Wang, Binghua Xue, Bingteng Xie, Jing Ma
Publikováno v:
Journal of Genetics and Genomics. 40:453-464
Embryonic germ (EG) cells are cultured pluripotent stem cells derived from the primordial germ cells (PGCs) that migrate from the dorsal mesentery of the hindgut to the developing genital ridge. In this study, the morphology of the porcine genital ri