Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Renee Whan"'
Autor:
Ivan Lukmantara, Fang Chen, Hoi Yin Mak, Armella Zadoorian, Ximing Du, Fanqian Nicole Xiao, Dougall MacMurray Norris, Elvis Pandzic, Renee Whan, Qing Zhong, Hongyuan Yang
Publikováno v:
Molecular Biology of the Cell. 33
The biogenesis of lipid droplets (LDs), key organelles for cellular lipid storage and homeostasis, remains poorly understood. Seipin is essential to normal LD biogenesis but exactly how it regulates LD initiation remains to be elucidated. Our previou
Autor:
Elvis Pandzic, Nihan Turgutoglu, Iveta Slapetova, Renee Whan, Sharon L. Wong, Ling Zhong, Shafagh A. Waters, Adam Jaffe, Nikhil T. Awatade, Laura K. Fawcett, Alexander Capraro
Publikováno v:
Journal of Cystic Fibrosis. 20:364-371
Background Patient-derived airway cells differentiated at Air Liquid Interface (ALI) are valuable models for Cystic fibrosis (CF) precision therapy. Different culture expansion methods have been established to extend expansion capacity of airway basa
Autor:
Katelin M. Allan, Jeffry Setiadi, Serdar Kuyucak, Laura K. Fawcett, John R. Widger, Renee Whan, Sharon L. Wong, Po-chia Chen, Michael Carnell, Adam Jaffe, Iveta Slapetova, Chee Y. Ooi, Shafagh A. Waters, Elvis Pandzic, Renate Griffith, Nikhil T. Awatade, Miro A. Astore
A significant challenge to making targeted CFTR modulator therapies accessible to all individuals with cystic fibrosis (CF) are many mutations in the CFTR gene that can cause CF, most of which remain uncharacterized. Here, we characterized the struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ae71c9509600baaccdbd97ba3ff84db
https://doi.org/10.1101/2021.08.11.456003
https://doi.org/10.1101/2021.08.11.456003
Autor:
Nick Di Girolamo, Renee Whan, Alexander Richardson, J. Guy Lyons, Stephanie L Watson, Erwin P. Lobo, Mijeong Park, Elvis Pandzic, Denis Wakefield
Publikováno v:
Stem Cell Reports, Vol 12, Iss 1, Pp 14-28 (2019)
Summary: It is thought that corneal epithelial injuries resolve by leading-edge cells “sliding” or “rolling” into the wound bed. Here, we challenge this notion and show by real-time imaging that corneal wounds initially heal by “basal cell
TMEM41B and VMP1 are scramblases and regulate the distribution of cholesterol and phosphatidylserine
Autor:
Shiqian Qi, Elvis Pandzic, Sarah E. Hancock, Yvette Celine Aw, Anthony S. Don, Ivan Lukmantara, Renee Whan, Yang Emma Li, Yichang Wang, Ximing Du, Tizhong Zhang, Nigel Turner, Holly P. McEwen, Xiuju Dong, Hongyuan Yang, Hoi Yin Mak, Yiqiong Yuan
Publikováno v:
The Journal of Cell Biology
VMP1 and TMEM41B, integral membrane proteins of the ER, regulate the formation of autophagosomes, lipid droplets, and lipoproteins. Here, Li, Wang, et al. show that they have phospholipid scramblase activity, which is essential to the normal distribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4283ddf20e8effa4d1df3c04c6fe66e3
https://hdl.handle.net/2123/25415
https://hdl.handle.net/2123/25415
Autor:
Sharon L. Wong, Shane R. Thomas, Bentotage S M Fernando, Renee Whan, Shafagh A. Waters, Wallace Bridge, Ling Zhong, Nikhil T. Awatade, Chris Hewson, Gene Hart-Smith, Adam Jaffe, Alexander Capraro, Elvis Pandzic
Publikováno v:
Antioxidants, Vol 9, Iss 1204, p 1204 (2020)
Antioxidants
Volume 9
Issue 12
Antioxidants
Volume 9
Issue 12
Systemic glutathione deficiency, inflammation, and oxidative stress are hallmarks of cystic fibrosis (CF), an inherited disease that causes persistent lung infections and severe damage to the respiratory system and many of the body organs. Improvemen
Autor:
Sharon L. Wong, Renee Whan, Nikhil T. Awatade, Adam Jaffe, Alexander Capraro, Shafagh A. Waters, Nihan Turgutoglu, Iveta Slapetova, Elvis Pandzic, Ling Zhong, Laura K. Fawcett
BackgroundPatient-derived airway cells differentiated at Air Liquid Interface (ALI) are valuable models for Cystic fibrosis (CF) precision therapy. Advances in culture techniques have improved expansion capacity of airway basal cells, while retaining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23302c83c9c8ad15d14768c64c7af55a
https://doi.org/10.1101/2020.05.29.120006
https://doi.org/10.1101/2020.05.29.120006
Autor:
Brendon Martinez, Renee Whan, Jonathan N. Vincent, Celine Heu, Ben Roediger, Daniel Stehle, Adam Cook, Rohit Jain, Dajiang Guo, Peyman Obeidy, Kathy On, Robert Feil, Shweta Tikoo, Florence Tomasetig, Wolfgang Weninger
Publikováno v:
Journal of Investigative Dermatology. 141:2090-2094.e6
Autor:
Mehul Gajwani, Miro Janco, Peyman Obeidy, Peter W. Gunning, Adelle C.F. Coster, Renee Whan, Philip R. Nicovich, Till Böcking, Katharina Gaus, Thomas L. Sobey
Publikováno v:
Cytoskeleton. 73:729-738
Reconstitution of actin filaments on surfaces for observation of filament-associated protein dynamics by fluorescence microscopy is currently an exciting field in biophysics. Here we examine the effects of attaching actin filaments to surfaces on the
Autor:
Madeline Campbell, Kate Poole, Renee Whan, Iman Jalilian, Florence Tomasetig, Vina D. L. Putra, Melissa L. Knothe Tate
Publikováno v:
Bio Protoc
Mechanomics, the mechanics equivalent of genomics, is a burgeoning field studying mechanical modulation of stem cell behavior and lineage commitment. Analogous to mechanical testing of a living material as it adapts and evolves, mapping of the mechan