Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Paul Frankel"'
Autor:
Paul Frankel, Marwa Mahmoud, Claire Walsh, Yuen Tam, Peter J. Scambler, Laura Wisniewski, Ian M. Evans, Ian Zachary, Simon Walker-Samuel
Publikováno v:
Cardiovascular Research. 118:1993-2005
AIM: The adapter protein p130Cas, encoded by the Bcar1 gene, is a key regulator of cell movement, adhesion, and cell cycle control in diverse cell types. Bcar1 constitutive knockout mice are embryonic lethal by embryonic days (E) 11.5-12.5, but the r
Autor:
Tamer Othman, Christopher Ruel, Paul Frankel, Alexander A. Merleev, Guillaume Luxardi, Emanual Maverakis, Mehrdad Abedi, Raghuveer Ranganathan, Jasmine Zain, Lihua E Budde, Matthew Mei, Aaron S Rosenberg, Rasmus T Hoeg, Caitlin Costello, Francine M. Foss, Basem M. William, H. Kent Holland, Miguel Villalona-Calero, Elad Sharon, Joseph M Tuscano
Publikováno v:
Blood. 140:9446-9447
Autor:
Colton Ladbury, George Somlo, Andy Dagis, Dongyun Yang, Saro Armenian, Joo Y. Song, Firoozeh Sahebi, Ricardo Spielberger, Leslie Popplewell, Pablo Parker, Stephen Forman, David Snyder, Amalia Rincon, An Liu, Paul Frankel, Jeffrey Wong
Publikováno v:
Transplantation and cellular therapy. 28(7)
Total body irradiation in combination with melphalan for multiple myeloma (MM) has been shown to be prohibitively toxic. To ameliorate toxicity, total marrow irradiation (TMI) has been administered as the sole ablative modality during the second cycl
Autor:
David L. Selwood, Paul Frankel, Tamas Yelland, Ian Zachary, Filipa Mota, Snezana Djordjevic, Constantina Fotinou, Andrew O’Leary, John Martin, Anastasia Patsiarika, Jennie A. Hutton, Jennifer Parker, A. W. Edith Chan
Publikováno v:
Chembiochem
Vascular endothelial growth factors (VEGFs) regulate significant pathways in angiogenesis, myocardial and neuronal protection, metabolism, and cancer progression. The VEGF‐B growth factor is involved in cell survival, anti‐apoptotic and antioxida
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
P130CAS/BCAR1 belongs to the CAS family of adaptor proteins, with important regulatory roles in cell migration, cell cycle control, and apoptosis. Previously, we and others showed that P130CAS mediates VEGF-A and PDGF signalling in vitro, but its car
Autor:
Anthony Rosario, Joanne E. Mortimer, Daniel Schmolze, Travis Y. Tu, Andrew Dagis, Roger Wang, Susan E. Yost, Ting-Fang He, Paul Frankel, Yuan Yuan, Shawn Solomon, Peter P. Lee, Yu Cao
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229955 (2020)
PLoS ONE
PLoS ONE
The evolutionary changes in immune profiles of triple negative breast cancer (TNBC) are not well understood, although it is known that immune checkpoint inhibitors have diminished activity in heavily pre-treated TNBC patients. This study was designed
Autor:
Tamer Othman, Pamela B. Allen, Paul Frankel, Shari Daniels, Lacolle Peters, Joseph Tuscano, Steven T. Rosen, Geoffrey Shouse, Elad Sharon, Alexey V. Danilov, Nora Ruel, Tanya Siddiqi, Leslie Popplewell, Alex F. Herrera, Stella Khoo
Publikováno v:
Blood. 138:1407-1407
Introduction: Diffuse large B-cell lymphomas (DLBCL) transformed from indolent B-cell non-Hodgkin lymphomas (B-NHL) or Richter transformation (RT) from chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL) are associated with a poor prognosis
Autor:
Yuriy Alexandrov, James McGinty, Ajay Bhargava, Erik Sahai, Paul M. W. French, Seth Flaxman, Guy A. Rutter, Samuel P. X. Davis, Gabriela da Silva Xavier, Sunil Kumar, Paul Frankel
Publikováno v:
Journal of Biophotonics
Optical projection tomography (OPT) is a 3D mesoscopic imaging modality that can utilize absorption or fluorescence contrast. 3D images can be rapidly reconstructed from tomographic data sets sampled with sufficient numbers of projection angles using
Autor:
Jacob Sayers, Paul Frankel, Vanessa Lowe, Ian Zachary, Nadia Mercader, Caroline Pellet-Many, Laura Wisniewski
Unlike adult mammals, zebrafish are able to naturally regenerate their heart. A key mechanism in zebrafish heart regeneration is the activation of the epicardium, leading to the establishment of a supporting scaffold for newly formed cardiomyocytes,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae2aa160226dee68c2005ebbc62faa9c
Autor:
Jasmine Zain, Christopher Ruel, Christina Poh, Brian A. Jonas, Francine M. Foss, Mehrdad Abedi, Paul Frankel, Edward M. Newman, Joseph Tuscano, Aaron S. Rosenberg, Lihua E. Budde, Basem M. William, Emily Schwab, Caitlin Costello
Publikováno v:
Blood. 134:760-760
Introduction Both blinatumomab and lenalidomide have proven, but limited, efficacy in relapsed/refractory (R/R) non-Hodgkin's lymphoma (NHL). Failure of blinatumomab to mediate durable responses is due to its inability to recruit competent cytotoxic