Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Pan Deng"'
Publikováno v:
Journal of Asia-Pacific Entomology. 23:7-16
In insects, an insulin-like peptide (ILP) triggers the formation of the insulin receptor (InR)/the insulin receptor substrate Chico complex. The complex then recruits downstream of receptor kinase (Drk) and phosphatidylinositol-3-kinase (PI3K) to ini
Autor:
Jessie B. Hoffman, Bernhard Hennig, Maria P. Kraemer, Andrew J. Morris, Pan Deng, Xu-Sheng Li, Chunyan Wang, Michael C. Petriello
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 1, Pp 45-53 (2020)
J Lipid Res
J Lipid Res
Elevated circulating levels of ceramides (Cers) are associated with increased risk of cardiometabolic diseases, and Cers may play a causative role in metabolic dysfunction that precedes cardiac events, such as mortality as a result of coronary artery
Publikováno v:
Pesticide Biochemistry and Physiology. 160:30-39
An exploration of novel control strategies for Leptinotarsa decemlineata is becoming more pressing given rapid evolution of insecticide resistance and rise of production loss of potato. Dietary delivery of bacterially expressed double-stranded RNA (d
Autor:
Ye Yang, Ronald C. Bruntz, Teresa W.-M. Fan, Levi J. Beverly, Yan Zhang, Chi V. Dang, Pan Deng, Zhen Qi, Parag P. Shah, Angela Mahan, Richard M. Higashi, Andrew N. Lane, Yelena Chernyavskaya, Huan Song
Publikováno v:
J Biol Chem
Nucleotide synthesis is essential to proliferating cells, but the preferred precursors for de novo biosynthesis are not defined in human cancer tissues. We have employed multiplexed stable isotope-resolved metabolomics to track the metabolism of [(13
Autor:
Kevin S. McIver, Nina M. van Sorge, Andrew G. Turner, Jeffrey S. Rush, Alistair G. McEwan, Alessandro Ruda, Rebecca J. Edgar, Andrew J. Morris, Natalia Korotkova, Yoann Le Breton, Ashton T. Belew, Najib M. El-Sayed, Pan Deng, Gérard Lambeau, Konstantin V. Korotkov, Mark J. Walker, Vincent P. van Hensbergen, Göran Widmalm
Publikováno v:
Nature chemical biology
Nature Chemical Biology, 15(5), 463. Nature Publishing Group
Nature Chemical Biology
Nature Chemical Biology, Nature Publishing Group, 2019, 15 (5), pp.463-471. ⟨10.1038/s41589-019-0251-4⟩
Nature Chemical Biology, 15(5), 463. Nature Publishing Group
Nature Chemical Biology
Nature Chemical Biology, Nature Publishing Group, 2019, 15 (5), pp.463-471. ⟨10.1038/s41589-019-0251-4⟩
Cell wall glycopolymers on the surface of Gram-positive bacteria are fundamental to bacterial physiology and infection biology. These structures have also gained interest as vaccine antigens, in particular for the human pathogens Group AStreptococcus
Functional characterization of ultraspiracle inLeptinotarsa decemlineatausing RNA interference assay
Publikováno v:
Insect Molecular Biology. 28:676-688
A heterodimer of ultraspiracle (USP) and ecdysone receptor (EcR) mediates 20-hydroxyecdysone (20E) signalling cascade to regulate insect moulting and metamorphosis. However, at least two questions remain to be addressed in terms of the molecular impo
Publikováno v:
Insect Science
A heterodimer of two nuclear receptors, ecdysone receptor (EcR) and ultraspiracle, mediates 20‐hydroxyecdysone (20E) signaling to modulate many aspects in insect life, such as molting and metamorphosis, reproduction, diapause and innate immunity. I
Mitochondrial UPR repression during Pseudomonas aeruginosa infection requires the bZIP protein ZIP-3
Autor:
Cole M. Haynes, Yunguang Du, Nandhitha Uma Naresh, Pan Deng, Jun Yu, Lilian T. Lamech, Read Pukkila-Worley, Lihua Julie Zhu
Publikováno v:
Proceedings of the National Academy of Sciences. 116:6146-6151
Mitochondria generate most cellular energy and are targeted by multiple pathogens during infection. In turn, metazoans employ surveillance mechanisms such as the mitochondrial unfolded protein response (UPR mt ) to detect and respond to mitochondrial
Publikováno v:
Insect Molecular Biology. 28:420-430
Broad-Complex (BrC) is a downstream target of both 20-hydroxyecdysone and juvenile hormone signalling. BrC regulates morphogenetic changes between nymphal instars in hemimetabolans, whereas it controls pupal commitment, pupal morphogenesis and inhibi
Publikováno v:
Bulletin of Entomological Research. 109:659-668
Dietary delivery of bacterially expressed double-stranded RNA (dsRNA) has a great potential for management ofLeptinotarsa decemlineata. An important first step is to discover possible RNA-interference (RNAi)-target genes effective against larvae, esp