Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Nabendu Pore"'
Autor:
Nabendu Pore, Kate Dixon, Hemant K. Mishra, Jeffrey S. Miller, Bruce Walcheck, Martin Felices
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Natural killer (NK) cells are innate cytotoxic lymphocytes that can recognize assorted determinants on tumor cells and rapidly kill these cells. Due to their anti-tumor effector functions and potential for allogeneic use, various NK cell platforms ar
Autor:
Diana Gibson, Andrew Spencer, Magdalini Migkou, Sikander Ailawadhi, Jeremy T. Larsen, Meletios A. Dimopoulos, Shaji Kumar, Marna Williams, Fujun Wang, Ioannis Kagiampakis, Farzana Walcott, Jeffrey A. Zonder, Lily Cheng, Nabendu Pore, Yu Jiang, Krista Kinneer, Shreerang Sirdesai, Manisha Bhutani, Andrew Yee, Anna Kalff
Publikováno v:
Blood. 136:26-27
Background: B-cell maturation antigen (BCMA) is widely expressed on normal plasma cells and malignant plasma cells in multiple myeloma (MM). MEDI2228 is an antibody-drug conjugate (ADC) that targets the extracellular domain of human BCMA with prefere
Autor:
Ronald Herbst, Elaine M. Hurt, Marlon Rebelatto, Danielle Michelle Townsley, Matt Flynn, Kevin Schifferli, Ravinder Tammali, Noel R. Monks, Nabendu Pore, Mary Jane Hinrichs, Steven Coats, David A. Tice, Rakesh Dixit, Borrok Martin J
Publikováno v:
Blood. 132:4071-4071
The neutral amino acid transporter, ASCT2, is frequently overexpressed in several cancers to sustain "glutamine addiction" of cancer cells. High expression of ASCT2 is often associated with poor disease prognosis. Immuno-histochemistry (IHC) on forma
Autor:
Fang Liu, Amit Maity, Nabendu Pore, Melissa L. Dowling, Gary D. Kao, K. Ranh Voong, Mijin Kim
Publikováno v:
Molecular Biology of the Cell. 17:585-597
Histone deacetylases mediate critical cellular functions but relatively little is known about mechanisms controlling their expression, including expression of HDAC4, a class II HDAC implicated in the modulation of cellular differentiation and viabili
Autor:
Hui-Kuo G. Shu, Nabendu Pore, Gilles Pagès, Donald M. O'Rourke, Amit Maity, Bin Li, Eric J. Bernhard, Julie Milanini-Mongiat, Shuang Liu, David Stokoe, Daphne A. Haas-Kogan
Publikováno v:
Molecular Biology of the Cell
Molecular Biology of the Cell, American Society for Cell Biology, 2004, 15 (11), pp.4841-53. ⟨10.1091/mbc.E04-05-0374⟩
Molecular Biology of the Cell, American Society for Cell Biology, 2004, 15 (11), pp.4841-53. ⟨10.1091/mbc.E04-05-0374⟩
International audience; Increased expression of vascular endothelial growth factor (VEGF) contributes to the growth of many tumors by increasing angiogenesis. Although hypoxia is a potent inducer of VEGF, we previously showed that epidermal growth fa
Publikováno v:
Journal of Biological Chemistry. 276:9519-9525
Oncogenic transformation and hypoxia both induceglut1 mRNA. We studied the interaction between theras oncogene and hypoxia in up-regulating glut1mRNA levels using Rat1 fibroblasts transformed with H-ras (Rat1-ras). Transformation with H-ras led to a
Publikováno v:
Molecular cancer research : MCR. 4(7)
The phosphoinositide 3-kinase (PI3K)/Akt pathway is commonly activated in cancer; therefore, we investigated its role in hypoxia-inducible factor-1α (HIF-1α) regulation. Inhibition of PI3K in U87MG glioblastoma cells, which have activated PI3K/Akt