Zobrazeno 1 - 4
of 4
pro vyhledávání: '"N. Kieu"'
Autor:
Michelle R. Dawson, Nithin Ravikumar, Daniel J. McGrail, Quang Minh N. Kieu, Kathleen M. McAndrews, Chandler P. Brandenburg
Publikováno v:
Biophysical Journal. 109:1334-1337
For a solid tumor to grow, it must be able to support the compressive stress that is generated as it presses against the surrounding tissue. Although the literature suggests a role for the cytoskeleton in counteracting these stresses, there has been
Publikováno v:
Physical biology. 12(2)
Despite major advances in the characterization of molecular regulators of cancer growth and metastasis, patient survival rates have largely stagnated. Recent studies have shown that mechanical cues from the extracellular matrix can drive the transiti
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 29(4)
A growing body of evidence suggests that the developmental process of epithelial-to-mesenchymal transition (EMT) is co-opted by cancer cells to metastasize to distant sites. This transition is associated with morphologic elongation and loss of cell-c
Publikováno v:
Journal of Cell Science.
Although current treatments for localized ovarian cancer are highly effective, this cancer still remains the most lethal gynecological malignancy, largely owing to the fact that it is often detected only after tumor cells leave the primary tumor. Cli