Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Michael Lee"'
Autor:
Sung-Hee Hwang, Michael Lee
Publikováno v:
Animal Cells and Systems
Animal Cells and Systems, Vol 24, Iss 1, Pp 17-25 (2020)
Animal Cells and Systems, Vol 24, Iss 1, Pp 17-25 (2020)
Several studies have revealed the functional importance of autophagy in both adipogenesis and carcinogenesis. Here, we investigated autophagy as a link between tumorigenesis and adipogenesis using 3T3-L1 cells, which have been shown to closely mimic
Autor:
Cecilia Östlund, Chun Chi Liang, Sarah B. Gibeley, Antonio Hernandez-Ono, William T. Dauer, Michael Lee, Tatyana Fedotova, Ji Yeon Shin, Henry N. Ginsberg, Howard J. Worman
Publikováno v:
J Clin Invest
Deciphering novel pathways regulating liver lipid content has profound implications for understanding the pathophysiology of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. Recent evidence suggests that the nuclear envelope is a si
Publikováno v:
Biochemical and Biophysical Research Communications. 513:234-241
Autophagy plays a contradictory role in cell survival and death. Here, we investigated changes in paclitaxel sensitivity of cells with an ATG5 gene-knockout (KO), incapable of synthesizing an E3 ubiquitin ligase necessary for autophagy. The ATG5 KO i
Publikováno v:
Biomolecules & Therapeutics
Melanoma cells have been shown to respond to BRAF inhibitors; however, intrinsic and acquired resistance limits their clinical application. In this study, we performed RNA-Seq analysis with BRAF inhibitor-sensitive (A375P) and -resistant (A375P/Mdr w
Autor:
Alexander P. Sobinoff, Michael Lee, Joshua A. M. Allen, Tatjana Kilo, Hilda A. Pickett, Raja S. Vasireddy, Christopher B. Nelson, Vivian Francília Silva Kahl
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Telomeres are repetitive regions of DNA bound by specialized proteins at the termini of linear chromosomes that prevent the natural chromosome ends from being recognized as DNA double strand breaks. Telomeric DNA is gradually eroded with each round o
Autor:
David R. Hill, Ramdane Harouaka, Julie M. Madden, Ebrahim Azizi, Laura S. Rozek, Michael Lee, Max S. Wicha, Shamileh Fouladdel, Justin A. Colacino, Julie L. Boerner, Maureen A. Sartor, Michael D. Brooks, Sean P. McDermott, Michele L. Cote
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 10, Iss 5, Pp 1596-1609 (2018)
Stem Cell Reports, Vol 10, Iss 5, Pp 1596-1609 (2018)
Summary During development, the mammary gland undergoes extensive remodeling driven by stem cells. Breast cancers are also hierarchically organized and driven by cancer stem cells characterized by CD44+CD24low/− or aldehyde dehydrogenase (ALDH) exp
Cyt-Geist: Current and Future Challenges in Cytometry: Reports of the CYTO 2018 Conference Workshops
Autor:
Kamila Czechowska, Giacomo Vacca, Cherie Green, Ruth M Barnard, Jaroslav Icha, Michael Nathan Hedrick, Gelo Victoriano Dela Cruz, Nicole E. Paul, Judith Arcidiacono, Andrew Filby, Jakob Zimmermann, Jonni S. Moore, Steven R. Bauer, Ruben Props, Jakub Nedbal, Yongliang Sun, Soren Ulrik Sonder, Christopher Hall, Caryn van Vreden, Cláudia Bispo, Paul K. Wallace, Rachel J. Errington, Jenny Molloy, Joanne Lannigan, Frederik Hammes, Johanna Ivaska, Thomas M. Ashhurst, Frederiek-Maarten Kerckhof, Michael Lee, Hyun-Dong Chang, Christian Kukat, Attila Tárnok, Nao Nitta, Robert S. Hoffman, Gert Van Isterdael, Lina Chakrabarti, John Sharpe, Michael Weber, Raluca Niesner, Christopher Groves, Peter Rubbens, Samson Rogers, Yanli Liu, Dominic Gagnon, Alessandra Vitaliti, Radhika Rayanki, Matthias Schiemann, Lili Wang, Robert Salomon, Grace Chojnowski, Rui Gardner, Bunny Cotleur, Derek H. Jones, John T. Elliott, Betsy Ohlsson-Wilhelm, Stefan Radtke, Maciej Cabanski, Ryan R. Brinkman, Michael Gregory, Henning Ulrich, Jennifer J. Stewart, Sheng Lin-Gibson, Dominic C. Jenner, Heba A. Degheidy, Virginia Litwin, Ziv Portat, Silas J. Leavesley, David Lanham, Susann Müller, Stephen P. Perfetto, Steven Eck, Aja M. Rieger, Diana L. Bonilla
Publikováno v:
Cytometry A
Czechowska, K, Lannigan, J, Wang, L, Arcidiacono, J, Ashhurst, T M, Barnard, R M, Bauer, S R, Bispo, C, Bonilla, D L, Brinkman, R R, Cabanski, M, Chang, H-D, Chakrabarti, L, Chojnowski, G, Cotleur, B, Degheidy, H, Dela Cruz, G V, Eck, S, Elliott, J, Errington, R, Filby, A, Gagnon, D, Gardner, R, Green, C, Gregory, M, Groves, C J, Hall, C, Hammes, F, Hedrick, M, Hoffman, R O, Icha, J, Ivaska, J, Jenner, D C, Jones, D, Kerckhof, F M, Kukat, C, Lanham, D, Leavesley, S, Lee, M, Lin-Gibson, S, Litwin, V, Liu, Y, Molloy, J, Moore, J S, Müller, S, Nedbal, J, Niesner, R, Nitta, N, Ohlsson-Wilhelm, B, Paul, N E, Perfetto, S, Porat, Z, Props, R, Radtke, S, Rayanki, R, Rieger, A, Rogers, S, Rubbens, P, Salomon, R, Schiemann, M, Sharpe, J, Sonder, S U, Stewart, J J, Sun, Y, Ulrich, H, Van Isterdael, G, Vitaliti, A, van Vreden, C, Weber, M, Zimmermann, J, Vacca, G, Wallace, P & Tárnok, A 2019, ' Cyt-Geist: Current and Future Challenges in Cytometry: Reports of the CYTO 2018 Conference Workshops ', Cytometry Part A, vol. 95, no. 6, pp. 598-644 . https://doi.org/10.1002/cyto.a.23777
Czechowska, K, Lannigan, J, Wang, L, Arcidiacono, J, Ashhurst, T M, Barnard, R M, Bauer, S R, Bispo, C, Bonilla, D L, Brinkman, R R, Cabanski, M, Chang, H-D, Chakrabarti, L, Chojnowski, G, Cotleur, B, Degheidy, H, Dela Cruz, G V, Eck, S, Elliott, J, Errington, R, Filby, A, Gagnon, D, Gardner, R, Green, C, Gregory, M, Groves, C J, Hall, C, Hammes, F, Hedrick, M, Hoffman, R O, Icha, J, Ivaska, J, Jenner, D C, Jones, D, Kerckhof, F M, Kukat, C, Lanham, D, Leavesley, S, Lee, M, Lin-Gibson, S, Litwin, V, Liu, Y, Molloy, J, Moore, J S, Müller, S, Nedbal, J, Niesner, R, Nitta, N, Ohlsson-Wilhelm, B, Paul, N E, Perfetto, S, Porat, Z, Props, R, Radtke, S, Rayanki, R, Rieger, A, Rogers, S, Rubbens, P, Salomon, R, Schiemann, M, Sharpe, J, Sonder, S U, Stewart, J J, Sun, Y, Ulrich, H, Van Isterdael, G, Vitaliti, A, van Vreden, C, Weber, M, Zimmermann, J, Vacca, G, Wallace, P & Tárnok, A 2019, ' Cyt-Geist: Current and Future Challenges in Cytometry: Reports of the CYTO 2018 Conference Workshops ', Cytometry Part A, vol. 95, no. 6, pp. 598-644 . https://doi.org/10.1002/cyto.a.23777
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::813c17049ba93a16648134b42fb793b6
https://hdl.handle.net/10453/137837
https://hdl.handle.net/10453/137837
Autor:
Joshua A. M. Allen, Christopher G. Tomlinson, Alexander P. Sobinoff, Michael Lee, Andrew J. Deans, Roger R. Reddel, Robert Lu, Julienne J O'Rourke, Christopher B. Nelson, Hilda A. Pickett
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
The collapse of stalled replication forks is a major driver of genomic instability. Several committed mechanisms exist to resolve replication stress. These pathways are particularly pertinent at telomeres. Cancer cells that use Alternative Lengthenin
Autor:
Byeal-I Han, Michael Lee
Publikováno v:
International Journal of Pharmacology. 12:19-27
Publikováno v:
2018 International Conference on System Science and Engineering (ICSSE).
We presents a microinjection system for gene delivery to planarian. The system consists of two parts: a planarian-fixing platform, which provides a low-temperature environment to make planarian become motionless for injection, and a nanoliter injecto