Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Mark P. Foster"'
Autor:
Mikhail Tarasov, Heather L. Struckman, Yusuf Olgar, Alec Miller, Mustafa Demirtas, Vladimir Bogdanov, Radmila Terentyeva, Andrew M. Soltisz, Xiaolei Meng, Dennison Min, Galina Sakuta, Izabella Dunlap, Antonia D. Duran, Mark P. Foster, Jonathan P. Davis, Dmitry Terentyev, Sándor Györke, Rengasayee Veeraraghavan, Przemysław B. Radwański
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 7 (2023)
Calmodulin (CaM) plays critical roles in cardiomyocytes, regulating Na+ (NaV) and L-type Ca2+ channels (LTCCs). LTCC dysregulation by mutant CaMs has been implicated in action potential duration (APD) prolongation and arrhythmogenic long QT (LQT) syn
Externí odkaz:
https://doaj.org/article/81e38ae2959b485889b6727a408e1abd
Autor:
Nancy L. Bartlett, Felicia Gomez, Matthew Mosior, Malachi Griffith, Anne Fischer, Michelle Becker-Hapak, Mark P. Foster, Melissa M. Berrien-Elliott, Alina D. Schmidt, Marcus Watkins, Amanda F. Cashen, Kilannin Krysiak, Kami J. Maddocks, Nina D. Wagner-Johnston, Jingqin Luo, Obi L. Griffith, Zachary L. Skidmore, Todd A. Fehniger, Sweta Desai, Jeffrey P. Ward
Publikováno v:
Blood
New therapies are needed for patients with relapsed/refractory (rel/ref) diffuse large B-cell lymphoma (DLBCL) who do not benefit from or are ineligible for stem cell transplant and chimeric antigen receptor therapy. The CD30-targeted, antibody-drug
Autor:
Ethan McClain, Sweta Desai, Amanda F. Cashen, Mark P. Foster, Peter Westervelt, Patrick Soon-Shiong, Michelle Becker-Hapak, Keith Stockerl-Goldstein, Jeffrey S. Miller, Miriam T. Jacobs, Mark A. Schroeder, Pamela Wong, Camille N. Abboud, Patrick Pence, Geoffrey L. Uy, Feng Gao, Claudio G. Brunstein, Melissa M. Berrien-Elliott, Meagan A. Jacoby, Iskra Pusic, Sarah Cooley, John F. DiPersio, Todd A. Fehniger
Publikováno v:
Blood. 139:1177-1183
Natural killer (NK) cells are a promising alternative to T cells for cancer immunotherapy. Adoptive therapies with allogeneic, cytokine-activated NK cells are being investigated in clinical trials. However, the optimal cytokine support after adoptive
Autor:
Pamela Wong, Jin-An Jiao, Timothy Schappe, Gilles M. Leclerc, Sweta Desai, Gabriela J. Muniz, Melissa M. Berrien-Elliott, Mark P. Foster, Lynne Marsala, Pallavi Chaturvedi, Carly Neal, Niraj Shrestha, Christian A. Echeverri, Xiaoyun Zhu, David A. Russler-Germain, Caitlin A. Prendes, Catherine M. Spanoudis, Todd A. Fehniger, Ethan McClain, Jack O. Egan, Michael J. Dee, Peter R. Rhode, Hing C. Wong, Jennifer Tran, Laritza L. Ramirez, Ryan P. Sullivan, Lijing You, Victor L. Gallo, Julia A. Wagner, Emily K. Jeng, Michelle Becker-Hapak, Patrick Pence
Publikováno v:
Cancer Immunol Res
Natural killer (NK) cells are a promising cellular therapy for cancer, with challenges in the field including persistence, functional activity, and tumor recognition. Briefly, priming blood NK cells with recombinant human (rh)IL-12, rhIL-15, and rhIL
Autor:
Timothy Schappe, Pamela Wong, Marco L. Davila, Neha Mehta-Shah, Amanda F. Cashen, Wei Meng, John F. DiPersio, Matthew L. Cooper, Brad S. Kahl, Maximilian Schaettler, Jennifer Tran, Melissa M. Berrien-Elliott, Feng Gao, Lynne Marsala, Carly Neal, Nancy D. Marin, Miriam Y. Kim, Margery Gang, Nancy L. Bartlett, Todd A. Fehniger, Mark P. Foster
Publikováno v:
Blood
Natural killer (NK) cells are a promising cellular immunotherapy for cancer. Cytokine-induced memory-like (ML) NK cells differentiate after activation with interleukin-12 (IL-12), IL-15, and IL-18, exhibit potent antitumor responses, and safely induc
Autor:
Mark P. Foster, Stevin Wilson, Vibhuti Wadhwa, Amanda J. Bird, Yi-Hsuan Liu, Carlos Cardona-Soto
Publikováno v:
Mol Microbiol
In Schizosaccharomyces pombe, the expression of the zrt1 zinc uptake gene is tightly regulated by zinc status. When intracellular zinc levels are low, zrt1 is highly expressed. However, when zinc levels are high, transcription of zrt1 is blocked in a
Autor:
Bryan Fisk, Pamela Wong, Jennifer A. Foltz, Margery Gang, Obi L. Griffith, Matthew Mosior, Nancy D. Marin, Jeffrey J. Bednarski, Lynne Marsala, Melissa M. Berrien-Elliott, Timothy Schappe, Amanda F. Cashen, Mark P. Foster, Alice Zhou, Miriam T. Jacobs, Clare Zimmerman, David A. Russler-Germain, Malachi Griffith, Celia C. Cubitt, Sweta Desai, Jennifer Tran, Michelle Becker-Hapak, Todd A. Fehniger, Ethan McClain, Allegra A. Petti, Patrick Pence, Saad M. Khan, Carly Neal
Publikováno v:
Blood. 138:3825-3825
Natural killer (NK) cells are innate lymphoid cells that mediate anti-tumor responses and exhibit innate memory following stimulation with IL-12, IL-15, and IL-18, thereby differentiating into cytokine-induced memory-like (ML) NK cells. ML NK cells h
Autor:
Kye Stachowski, Mark P. Foster
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 77:a292-a292
Autor:
Amanda F. Cashen, Sweta Desai, Mark P. Foster, Tim Schappe, Michelle Becker-Hapak, Carly Neal, Todd A. Fehniger, Ethan McClain, Melissa M. Berrien-Elliott, Jennifer A. Foltz
Publikováno v:
Blood. 134:1954-1954
Natural killer (NK) cells exhibit innate memory or memory-like responses following stimulation with haptens, viruses, or cytokines. Human memory-like (ML) NK cells differentiate following a short-term activation with IL-12, IL-15, and IL-18, and have
Autor:
Wong Pamela, Melissa M. Berrien-Elliott, Tim Schappe, Todd A. Fehniger, Mark P. Foster, Margery Gang, Carly Neal, Lynne M Marsala, Wei M Meng, Maximilian M Schaettler, Nancy M Marin Agudelo
Publikováno v:
Blood. 134:869-869
NK cells are cytotoxic innate lymphoid cells that mediate anti-tumor responses and traffic to most tissues. NK cells activated briefly with IL-12, IL-15, and IL-18 differentiate into memory-like (ML) NK cells with enhanced anti-tumor effects, which h