Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jong Seok Moon"'
Autor:
Augustine M.K. Choi, Mi-Ae Park, Mijin Yun, Chun K. Kim, Kiichi Nakahira, Jong Seok Moon, Maria Haslip, Ilias I. Siempos, Judie A. Howrylak, Patty J. Lee, Seonmin Lee, Stefan W. Ryter
Publikováno v:
Journal of Clinical Investigation. 133
Cellular lipid metabolism has been linked to immune responses; however, the precise mechanisms by which de novo fatty acid synthesis can regulate inflammatory responses remain unclear. The NLRP3 inflammasome serves as a platform for caspase-1–depen
Autor:
Myoung Seok Ko, Sean M. Hartig, Seong Who Kim, In Jeoung Baek, David A. Bader, Ki Up Lee, Joong Yeol Park, Chul-Ho Lee, Eun Hee Koh, David D. Moore, Inkyu Lee, Jung Eun Jang, Seung Ho Heo, Ji Young Yun, Jaeseok Han, Jae Man Lee, Jung Jin Hwang, Eun Gyoung Hong, Seung Eun Lee, Jong Seok Moon, Un Jung Kang
Publikováno v:
Autophagy, vol 17, iss 5
Autophagy
article-version (VoR) Version of Record
Autophagy
article-version (VoR) Version of Record
Although macroautophagy/autophagy deficiency causes degenerative diseases, the deletion of essential autophagy genes in adipocytes paradoxically reduces body weight. Brown adipose tissue (BAT) plays an important role in body weight regulation and met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee733fa26d884e97dd8be1aa015d7656
https://escholarship.org/uc/item/7651w2nw
https://escholarship.org/uc/item/7651w2nw
Autor:
Haesung Yang, Jung Han Kim, Jong-Seok Moon, Junhyung Kim, Min Woo Park, Sun Shin Yi, Hyeon Woo Cha, Napissara Boonpraman, Ik Dong Yoo, Sunmi Yoon
Publikováno v:
Redox Biology, Vol 41, Iss, Pp 101947-(2021)
Redox Biology
Redox Biology
Oxidative stress has been implicated in the pathogenesis of Alzheimer's disease (AD). Mitochondrial dysfunction is linked to oxidative stress and reactive oxygen species (ROS) in neurotoxicity during AD. Impaired mitochondrial metabolism has been ass
Autor:
Trinh Van Ngu, Chae-Bin Kim, Sujung Song, Cheolwon Choi, Seulgi Yoon, Jong-Seok Moon, Javaria Munir, JaeWook Han, Hyesu Moon, Seongho Ryu, Penchatr Diskul-Na-Ayudthaya, Yun-Ui Bae, Se bin Park
Publikováno v:
RNA Biology. :1-10
Techniques to isolate the small RNA fraction (
Autor:
Soo Han Bae, Jaekyoon Shin, Young Sam Kim, Younghee Kwon, Jeongho Kwon, Joo Heon Yoon, Ji Hwan Oh, Atsushi Miyawaki, Min-Ji Kim, Augustine M.K. Choi, Ji-Hwan Ryu, Jong Seok Moon, Jae Chan Ryu, Min Goo Lee, Kyubo Kim, Chang Hoon Kim, Stefan W. Ryter, Sue Goo Rhee
Publikováno v:
Autophagy. 12:1272-1291
Proper regulation of mitophagy for mitochondrial homeostasis is important in various inflammatory diseases. However, the precise mechanisms by which mitophagy is activated to regulate inflammatory responses remain largely unknown. The NLRP3 (NLR fami
Autor:
Ji Hun Jeong, Kiichi Nakahira, Ha young Shin, Seongho Ryu, Jong-Seok Moon, Do won Lee, Jaeseok Han
Publikováno v:
Biochemical and biophysical research communications. 493(2)
Low dose of carbon monoxide (CO) has anti-inflammatory role through various signaling pathways. Cellular metabolism has been implicated in the activation of inflammation in immune cells. However, the mechanisms by which CO-dependent metabolic regulat
Autor:
Shu Hisata, Mi-Ae Park, Stefan W. Ryter, Augustine M.K. Choi, Kiichi Nakahira, Gina M. DeNicola, Jong Seok Moon
Publikováno v:
Cell Reports, Vol 12, Iss 1, Pp 102-115 (2015)
SummaryThe mammalian target of rapamycin complex 1 (mTORC1) regulates activation of immune cells and cellular energy metabolism. Although glycolysis has been linked to immune functions, the mechanisms by which glycolysis regulates NLRP3 inflammasome
Autor:
Sung Soo Jung, Kiichi Nakahira, Augustine M.K. Choi, Jin Fu Xu, Stefan W. Ryter, Jong Seok Moon, Emeka Ifedigbo
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 308:L1058-L1067
Inflammasomes are cytosolic protein complexes that promote the cleavage of caspase-1, which leads to the maturation and secretion of proinflammatory cytokines, including interleukin-1β (IL-1β) and IL-18. Among the known inflammasomes, the nucleotid
Aging is associated with metabolic diseases such as type 2 diabetes mellitus, cardiovascular disease, cancer, and neurodegeneration. Aging contributes to common processes including metabolic dysfunction, DNA damage, and reactive oxygen species genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d782bb3f354ed56520331233a21fdb7
https://europepmc.org/articles/PMC5449513/
https://europepmc.org/articles/PMC5449513/
Autor:
Michael Jakun Koo, Jong Seok Moon, Heather W. Stout-Delgado, Joo Heon Yoon, Kiichi Nakahira, Kuei-Pin Chung, Maria A. Pabon, Stefan W. Ryter, Augustine M.K. Choi, Kristen T. Rooney, Gina M. DeNicola
Publikováno v:
Nature medicine. 22(9)
Altered metabolism has been implicated in the pathogenesis of inflammatory diseases. NADPH oxidase 4 (NOX4), a source of cellular superoxide anions, has multiple biological functions that may be of importance in inflammation and in the pathogenesis o