Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jinying Piao"'
Autor:
Takuya Oyaizu, Toshio Miyata, Yoshinori Asou, Yoichi Ezura, Aidehamu Aihemaiti, Kunikazu Tsuji, Naoki Yamamoto, Shingo Sato, Jinying Piao, Atsushi Okawa, Hiroki Ochi
Publikováno v:
Biochemical and biophysical research communications. 534
Sarcopenia is among the most common medical problems of the aging population worldwide and a major social concern. Here, we explored the therapeutic potential of TM5484, a novel orally available PAI-1 inhibitor, to prevent sarcopenia. The sarcopenic
Autor:
Yasushi Hara, Jinying Piao, Daisuke Koga, Yoshinori Asou, Sadao Morita, Munetaka Iwata, Zulipiya Aibibula, Atsushi Okawa, Maierhaba Ailixiding
Publikováno v:
Biochemical and Biophysical Research Communications. 466(3):319-326
Osteoarthritis (OA) is a chronic degenerative joint disorder commonly associated with metabolic syndrome. As ageing and obesity has a great impact on the initiation/severity of OA, herein we sought to investigate the involvement of Sirt6 in the cross
Autor:
Yasushi Hara, Yoshinori Asou, Jinying Piao, Munetaka Iwata, Zulipiya Aibibula, Atsushi Okawa, Maierhaba Ailixiding
Publikováno v:
Biochemical and biophysical research communications. 472(1)
A metabolic syndrome (MetS) is accompanied by hyperuricemia, during which xanthine oxidoreductase (XOR) catalyzes the production of uric acid. In the cohort study, a correlation between uric acid concentration in the synovial fluid and osteoarthritis
Autor:
Maierhaba Ailixiding, Yasushi Hara, Yoshinori Asou, Munetaka Iwata, Zulipiya Aibibula, Guangwen Jin, Atsushi Okawa, Hiroki Ochi, Jinying Piao
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 9, p e0162794 (2016)
PLoS ONE, Vol 11, Iss 9, p e0162794 (2016)
Obesity is a risk factor for osteoarthritis (OA). To investigate the roles of increased mechanical loading in the onset of obesity-induced OA, knee joints were histologically analyzed after applying a tail suspension (TS) model to a high-fat diet (HF
Autor:
Munetaka Iwata, Daisuke Koga, Shu Takeda, Yoshinori Asou, Kunikazu Tsuji, Atsushi Okawa, Hiroki Ochi, Jinying Piao, Sadao Morita
Publikováno v:
Scientific Reports
Sirtuin 6 (Sirt6) is a mammalian homologue of NAD+-dependent histone deacetylase Sir2. Although Sirt6−/− mice exhibit growth retardation, the role of Sirt6 in cartilage metabolism is unclear. The aim of this study was to investigate the Sirt6 sig