Zobrazeno 1 - 10
of 3 952
pro vyhledávání: '"James, M"'
Autor:
Ivo Siekmann, James M. Osborne
Publikováno v:
Frontiers in Applied Mathematics and Statistics, Vol 9 (2023)
Externí odkaz:
https://doaj.org/article/2a4885ec0ce747d98898ec4a910be93b
Autor:
Daniel Frank, Sarah E. Garnish, Jarrod J. Sandow, Ashley Weir, Lin Liu, Elise Clayer, Lizeth Meza, Maryam Rashidi, Simon A. Cobbold, Simon R. Scutts, Marcel Doerflinger, Holly Anderton, Kate E. Lawlor, Najoua Lalaoui, Andrew J. Kueh, Vik Ven Eng, Rebecca L. Ambrose, Marco J. Herold, Andre L. Samson, Rebecca Feltham, James M. Murphy, Gregor Ebert, Jaclyn S. Pearson, James E. Vince
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104632- (2022)
Summary: Pathogen recognition and TNF receptors signal via receptor interacting serine/threonine kinase-3 (RIPK3) to cause cell death, including MLKL-mediated necroptosis and caspase-8-dependent apoptosis. However, the post-translational control of R
Externí odkaz:
https://doaj.org/article/3caa971ec6024a6691ed27fdce5d0571
Autor:
Catia L. Pierotti, Annette V. Jacobsen, Christoph Grohmann, Ruby K. Dempsey, Nima Etemadi, Joanne M. Hildebrand, Cheree Fitzgibbon, Samuel N. Young, Katherine A. Davies, Wilhelmus J. A. Kersten, John Silke, Kym N. Lowes, Hélène Jousset Sabroux, David C. S. Huang, Mark F. van Delft, James M. Murphy, Guillaume Lessene
Publikováno v:
Biochemical Journal. 480:665-684
Necroptosis is a mode of programmed, lytic cell death that is executed by the mixed lineage kinase domain-like (MLKL) pseudokinase following activation by the upstream kinases, receptor-interacting serine/threonine protein kinase (RIPK)-1 and RIPK3.
Autor:
James M. Ntambi, Xueqing Liu, Maggie S. Burhans, Ahmed ALjohani, Ebru Selin Selen, Mugagga Kalyesubula, Fariba Assadi-Porter
Publikováno v:
Biochemical and Biophysical Research Communications. 651:62-69
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1998 Dec 01. 95(25), 14729-14732.
Externí odkaz:
https://www.jstor.org/stable/46611
Autor:
Emma C. Tovey Crutchfield, Sarah E. Garnish, Jessica Day, Holly Anderton, Shene Chiou, Anne Hempel, Cathrine Hall, Komal M. Patel, Pradnya Gangatirkar, Katherine R. Martin, Connie S. N. Li Wai Suen, Alexandra L. Garnham, Andrew J. Kueh, Ian P. Wicks, John Silke, Ueli Nachbur, Andre L. Samson, James M. Murphy, Joanne M. Hildebrand
Publikováno v:
Cell Death & Differentiation. 30:1059-1071
MLKL and RIPK3 are the core signaling proteins of the inflammatory cell death pathway, necroptosis, which is a known mediator and modifier of human disease. Necroptosis has been implicated in the progression of disease in almost every physiological s
Autor:
Tung T. Le, Meiling Wu, Joyce H. Lee, Neti Bhatt, James T. Inman, James M. Berger, Michelle D. Wang
Publikováno v:
Nature Chemical Biology. 19:641-650
Etoposide is a broadly employed chemotherapeutic and eukaryotic topoisomerase II poison that stabilizes cleaved DNA intermediates to promote DNA breakage and cytotoxicity. How etoposide perturbs topoisomerase dynamics is not known. Here we investigat
Publikováno v:
Journal of Anatomy. 242:927-952
Autor:
Hongxia Chen, Yunpeng Bai, Michihiro Kobayashi, Shiyu Xiao, Wenjie Cai, Sergio Barajas, Sisi Chen, Jinmin Miao, Frederick Nguele Meke, Sasidhar Vemula, James P. Ropa, James M. Croop, H. Scott Boswell, Jun Wan, Yuzhi Jia, Huiping Liu, Loretta S. Li, Jessica K. Altman, Elizabeth A. Eklund, Peng Ji, Wei Tong, Hamid Band, Danny T. Huang, Leonidas C. Platanias, Zhong-Yin Zhang, Yan Liu
Publikováno v:
Blood. 141:244-259
Acute myeloid leukemia (AML) is an aggressive blood cancer with poor prognosis. FMS-like tyrosine kinase receptor-3 (FLT3) is one of the major oncogenic receptor tyrosine kinases aberrantly activated in AML. Although protein tyrosine phosphatase PRL2
Publikováno v:
American Journal of Physiology-Cell Physiology. 323:C1664-C1680
The aim of this study was to examine the effect of TNFα (i.e., a predominant proinflammatory cytokine produced during chronic gut inflammation) on colonic uptake of thiamin pyrophosphate (TPP) and free thiamin, forms of vitamin B1 that are produced