Zobrazeno 1 - 10
of 34
pro vyhledávání: '"J. Lam"'
Publikováno v:
Journal of Investigative Dermatology. 143:S157
Autor:
Ralph Andre, Janos Kriston-Vizi, Gillian P. Bates, Simon Heales, Rhia Ghosh, Robert K. Heaton, Alison Wood-Kaczmar, Lucianne Dobson, Robin Ketteler, Amanda J. Lam, Iain P. Hargreaves, Edward J Smith, Sarah J. Tabrizi, Eva C. Sirinathsinghji, Frank Herrmann, Andrey Y. Abramov
Publikováno v:
The FASEB Journal
Robust cellular models are key in determining pathological mechanisms that lead to neurotoxicity in Huntington's disease (HD) and for high throughput pre‐clinical screening of potential therapeutic compounds. Such models exist but mostly comprise n
Autor:
David T.S. Lin, Jana Gillies, Avery J. Lam, Prakruti Uday, Megan K. Levings, Michael S. Kobor, Anne M. Pesenacker
SummaryTreg cell therapy is a promising curative approach for a variety of immune-mediated conditions. CRISPR-based genome editing allows precise insertion of transgenes through homology-directed repair, but use in human Tregs has been limited. We re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a2e3bd294e3a61078cbb0991603587e
https://doi.org/10.1101/2021.01.16.426937
https://doi.org/10.1101/2021.01.16.426937
Publikováno v:
Bio Protoc
Regulatory T cells (Tregs) suppress immune responses via a variety of mechanisms and can be used as a cellular therapy to induce tolerance. The function of Tregs is commonly assessed in vitro using assays that measure suppression of effector T cell p
Autor:
Emilie E. L. Muller, Nathan D. Hicks, Karoline Faust, Paul Keim, James M. Schupp, Susana Martinez Arbas, Shaman Narayanasamy, Haixu Tang, Cedric Christian Laczny, Malte Herold, Lance B. Price, Yuzhen Ye, Patrick May, Robert L. Moritz, John D. Gillece, Tony J. Lam, Sujun Li, Michael R. Hoopmann, Cindy M. Liu, Paul Wilmes, Laura Lebrun, Alexander Skupin, Benoit J. Kunath
Publikováno v:
Nature Microbiology
Nature Microbiology, Nature Publishing Group, 2020, pp.123-135 + 10 figures. ⟨10.1038/s41564-020-00794-8⟩
Nature Microbiology, Nature Publishing Group, 2020, pp.123-135 + 10 figures. ⟨10.1038/s41564-020-00794-8⟩
Viruses and plasmids (invasive mobile genetic elements (iMGEs)) have important roles in shaping microbial communities, but their dynamic interactions with CRISPR-based immunity remain unresolved. We analysed generation-resolved iMGE–host dynamics s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dac7506d8c22c3f208878bdbf2fdcd2
http://orbilu.uni.lu/handle/10993/45371
http://orbilu.uni.lu/handle/10993/45371
Autor:
Anne M. Pesenacker, Raewyn Broady, Megan K. Levings, Nicholas A.J. Dawson, Laura Cook, Avery J. Lam, Romy E. Hoeppli
Publikováno v:
European Journal of Immunology. 48:1415-1419
We optimized a method to detect FOXP3 by mass cytometry and compared the resulting data to conventional flow cytometry. We also demonstrated the utility of the protocol to profile antigen-specific Tregs from whole blood, or Tregs from tissues such as
Autor:
Renajd Rrapi, Emily D. Nguyen, Teja Chakrala, Sidharth Chand, J. Lam, Z. Yi, Daniela Kroshinsky, Sarah Song
Publikováno v:
Journal of Investigative Dermatology. 141:S54
Autor:
Sidharth Chand, Teja Chakrala, Emily D. Nguyen, Sarah Song, J. Lam, Renajd Rrapi, Z. Yi, Daniela Kroshinsky
Publikováno v:
Journal of Investigative Dermatology. 141:S55
Autor:
Emily D. Nguyen, Sarah Song, J. Lam, Daniela Kroshinsky, Renajd Rrapi, Z. Yi, Teja Chakrala, Sidharth Chand
Publikováno v:
Journal of Investigative Dermatology. 141:S76
Autor:
J. Lam, Aaron B. Carmody, Nicholas F. Noriea, Mary M. Weber, Ted Hackstadt, Bryan Hansen, Forrest H. Hoyt, Cheryl A. Dooley, Gail L. Sturdevant
Publikováno v:
Cell Reports, Vol 19, Iss 7, Pp 1406-1417 (2017)
Chlamydia trachomatis is a human pathogen associated with significant morbidity worldwide. As obligate intracellular parasites, chlamydiae must survive within eukaryotic cells for sufficient time to complete their developmental cycle. To promote host