Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Graeme J. Koelwyn"'
Publikováno v:
Nat Metab
Unhealthful lifestyle factors, such as obesity, disrupt organismal homeostasis and accelerate cancer pathogenesis, partly through metabolic and immunological dysregulation. Exercise is a prototypical strategy that maintains and restores homeostasis a
Publikováno v:
The Journal of Experimental Medicine
Ley et al. provide a review of the technology and accomplishments of dynamic imaging of myeloid cells in atherosclerosis.
Intravital imaging is an invaluable tool for understanding the function of cells in healthy and diseased tissues. It provid
Intravital imaging is an invaluable tool for understanding the function of cells in healthy and diseased tissues. It provid
Autor:
Edward A. Fisher, Martin Schlegel, Daniel Peled, Lauren Beckett, Alireza Khodadadi-Jamayran, Kathryn J. Moore, Lianne C Shanley, Huilin Li, Chiara Giannarelli, Coen van Solingen, Monika Sharma, Graeme J. Koelwyn, Karishma Rahman, Emily J. Brown, Milessa Silva Afonso
Publikováno v:
Circ Res
Rationale: MicroRNA-33 (miR-33 [post-transcriptionally in the rationale]) post-transcriptionally represses genes involved in lipid metabolism and energy homeostasis. Targeted inhibition of miR-33 increases plasma HDL (high-density lipoprotein) choles
Autor:
Coen van Solingen, Mala Gunadasa-Rohling, David R. F. Carter, Daniela Pezzolla, Antoine-Emmanuel Saliba, Emma M Corr, Alastair L. Corbin, Daniel C. Anthony, Raman Dhaliwal, Kathryn J. Moore, Clément Cochain, Mayooran Shanmuganathan, Thomas Krausgruber, G Melling, Eleanor Hogg, Errin Johnson, Laurienne Edgar, Irina A. Udalova, Keith M. Channon, Paul R. Riley, Charlotte Lee, Robin P. Choudhury, Christoph Bock, Graeme J. Koelwyn, Adam Costin, Naveed Akbar, Adam Braithwaite, Daan Paget, Joey Riepsaame, Abhirup Banerjee
Acute myocardial infarction rapidly increases blood neutrophils (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f44ebb9f455e44fed26faac265626fd8
https://doi.org/10.1101/2020.12.03.20242875
https://doi.org/10.1101/2020.12.03.20242875
Autor:
Monika Sharma, Ravichandran Ramasamy, Tarik Hadi, Ludovic Boytard, Edward A. Fisher, Bhama Ramkhelawon, Susan Hutchison, Westley Spiro, Bo Yan, Lena Seifert, Russell Simon, Graeme J. Koelwyn, Mireille Ouimet, Kathryn J. Moore
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
During obesity, macrophages infiltrate the visceral adipose tissue and promote inflammation that contributes to type II diabetes. Evidence suggests that the rewiring of cellular metabolism can regulate macrophage function. However, the metabolic prog
Autor:
Susan Babunovic, Milessa Silva Afonso, Monika Sharma, Karishma Rahman, Kathryn J. Moore, Lauren Beckett, Mireille Ouimet, Coen van Solingen, Edward A. Fisher, Graeme J. Koelwyn, P. Martin Schlegel
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38
Previous studies have identified microRNA-33 (miR-33) as a key regulator of metabolic gene pathways involved in cholesterol and fatty acid homeostasis. Inhibition of miR-33 promotes the regression of atherosclerosis, in part, by enhancing plasma HDL
Publikováno v:
Nature immunology. 19(6)
After activation, cells of the myeloid lineage undergo robust metabolic transitions, as well as discrete epigenetic changes, that can dictate both ongoing and future inflammatory responses. In atherosclerosis, in which macrophages play central roles
Autor:
Kathryn J. Moore, Jurriën Prins, Lesca M. Holdt, C. Van Solingen, Lars Maegdefessel, Elizabeth J. Hennessy, Kaitlyn R Scacalossi, Milessa Silva Afonso, Bhama Ramkhelawon, Daniel Teupser, Mireille Ouimet, Graeme J. Koelwyn
Publikováno v:
Atherosclerosis. 287:e287
Autor:
Graeme J. Koelwyn, Bhama Ramkhelawon, Elizabeth J. Hennessy, Lesca M. Holdt, Maryem A. Hussein, Daniel Tupser, Katey J. Rayner, Kathryn J. Moore, Coen van Solingen, Ryan E. Temel, Michael J. Garabedian, Mireille Ouimet
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 36
Cholesterol homeostasis is fundamental to human health, and is thus, tightly regulated. MicroRNAs exert potent effects on biological pathways, including cholesterol metabolism, by repressing genes with related functions. We reasoned that this mode of