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of 4
pro vyhledávání: '"Grady Phillips"'
Autor:
Anna Lysakowski, Maria C. Perez-Flores, Grady Phillips, Jeong-Han Lee, Saeyeon Ju, Ebenezer N. Yamoah, Seojin Park, Michael Anne Gratton, Mincheol Kang, Guy Perkins
Publikováno v:
J Neurosci
Organelle crosstalk is vital for cellular functions. The propinquity of mitochondria, ER, and plasma membrane promote regulation of multiple functions, which include intracellular Ca2+flux, and cellular biogenesis. Although the purposes of apposing m
Autor:
Brianna Dufek, Edward Doyle, Michael Anne Gratton, Ross Coenen, Daniel T. Meehan, Brendan J Smyth, Jacob Madison, Gina Samuelson, Kevin Wilhelm, Dominic Cosgrove, Grady Phillips, Duane Delimont
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0237907 (2020)
PLoS ONE
PLoS ONE
Previous work demonstrates that the hearing loss in Alport mice is caused by defects in the stria vascularis. As the animals age, progressive thickening of strial capillary basement membranes (SCBMs) occurs associated with elevated levels of extracel
Autor:
Shiguang Liu, Duane Delimont, Brianna Dufek, Michael Anne Gratton, Linda Cheung, Wenping Song, Grady Phillips, Daniel T. Meehan, Dominic Cosgrove
Publikováno v:
Kidney International. 90:300-310
Recent work demonstrates that Alport glomerular disease is mediated through a biomechanical strain-sensitive activation of mesangial actin dynamics. This occurs through a Rac1/CDC42 cross-talk mechanism that results in the invasion of the subcapillar
Autor:
Duane Delimont, Grady Phillips, Daniel T. Meehan, Dominic Cosgrove, Brianna Dufek, Marisa Zallocchi, Michael Anne Gratton
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99083 (2014)
PLoS ONE
PLoS ONE
It has been known for some time that laminins containing α1 and α2 chains, which are normally restricted to the mesangial matrix, accumulate in the glomerular basement membranes (GBM) of Alport mice, dogs, and humans. We show that laminins containi