Zobrazeno 1 - 10
of 268
pro vyhledávání: '"Finkel, A."'
Autor:
Morie A. Gertz, Rafat Abonour, Sarah N. Gibbs, Muriel Finkel, Heather Landau, Suzanne Lentzsch, Grace Lin, Anuj Mahindra, Tiffany P. Quock, Cara A. Rosenbaum, Michael Rosenzweig, Surbhi Sidana, Sascha A. Tuchman, Ronald Witteles, Irina Yermilov, Michael S. Broder
Publikováno v:
Blood. 140:13129-13131
Autor:
Aharon Nachshon, Michal Schwartz, Yoav Lubelsky, Hadas Tamir, Tal Fisher, Roni Winkler, Batsheva Rozman, Orel Mizrahi, Yfat Yahalom-Ronen, Nir Paran, Igor Ulitsky, Yaara Finkel, Boris Slobodin, Binyamin Zuckerman, Noam Stern-Ginossar, Tomer Israely, Avi Gluck
Publikováno v:
Nature
The coronavirus SARS-CoV-2 is the cause of the ongoing pandemic of COVID-191. Coronaviruses have developed a variety of mechanisms to repress host mRNA translation to allow the translation of viral mRNA, and concomitantly block the cellular innate im
Autor:
Hans Sebastian, Steven E. Finkel
Publikováno v:
Microbiology Spectrum. 10
During stationary phase in Escherichia coli, the expression of the ribosome modulation factor (RMF) protein participates in the dimerization of two 70S ribosomes, ultimately creating a 100S particle. 100S ribosomes are commonly thought to function to
Autor:
Yu Jiang, Ferhan Tuncer, Brydie R. Huckestein, Yanwen Chen, Travis Lear, Jason R. Kennerdell, Yuan Liu, Matthew K. Nguyen, Satdarshan P.S. Monga, Rama K. Mallampalli, Toren Finkel, Bill B. Chen, Michael J. Jurczak, Bo Lin, Christopher P. O'Donnell, Mads Breum Larsen
Publikováno v:
Nature chemical biology
The adenosine monophosphate (AMP)-activated protein kinase (Ampk) is a central regulator of metabolic pathways, and increasing Ampk activity has been considered to be an attractive therapeutic target. Here, we have identified an orphan ubiquitin E3 l
Autor:
Travis Lear, Karina Lockwood, Áine Boudreau, Mads Larsen, Bo Lin, Stacey Sukoff-Rizzo, Yuan Liu, Toren Finkel, Bill Chen
Publikováno v:
Journal of Biological Chemistry. 299:104111
Autor:
Calista Allen, Steven E. Finkel
Publikováno v:
Microbiology spectrum. 10(1)
The bioluminescent marine bacterium Vibrio harveyi can exist within a host, acting as a mutualist or a parasitic microbe, and as planktonic cells in open seawater. This study demonstrates the ability of V. harveyi populations to survive and adapt und
Autor:
Michael J. Jurczak, Yuan Liu, Ferhan Tuncer, Tracy Tabib, John Evankovich, Christina Morse, Toren Finkel, Jason R. Kennerdell, Robert Lafyatis, Travis Lear, Bill B. Chen, Karina C. Lockwood, Mads Breum Larsen, Eleanor Valenzi, Daniel J. Kass
Publikováno v:
J Biol Chem
Systemic scleroderma (SSc) is an autoimmune disease that affects over 2.5 million people globally. SSc results in dysfunctional connective tissues with excessive profibrotic signaling, affecting skin, cardiovascular, and particularly lung tissue. Ove
Autor:
Toren Finkel, Hiroshi Kataoka, Daniela Malide, Jason C. Kovacic, Maria Paola Santini, Gaurav Pandey, Ilsa I. Rovira, Valentina d'Escamard, Aya Nomura-Kitabayashi, Richard P. Harvey, Gabriel E. Hoffman, Jordi Ochando
Publikováno v:
Cell Reports, Vol 30, Iss 2, Pp 555-570.e7 (2020)
Summary: PDGFRα+ mesenchymal progenitor cells are associated with pathological fibro-adipogenic processes. Conversely, a beneficial role for these cells during homeostasis or in response to revascularization and regeneration stimuli is suggested, bu
Autor:
Dina A. Finkel, Edmund F. La Gamma, Lakshmipramoda Bapatla, Mitchell S. Cairo, Furong Hu, Shetal Shah, Govindaiah Vinukonda, Deepti Purohit, Priyadarshani Giri, Yanling Liao, Karen Hussein, Larisa Ivanova, Muhammed T. Zia
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 11, Pp 1157-1169 (2019)
Stem Cells Translational Medicine
Stem Cells Translational Medicine
Intraventricular hemorrhage (IVH) is a severe complication of preterm birth, which leads to hydrocephalus, cerebral palsy, and mental retardation. There are no available therapies to cure IVH, and standard treatment is supportive care. Unrestricted s
Publikováno v:
FASEB J
Mitochondria are intimately connected to cell fate and function. Here, we review how these intracellular organelles participate in the induction and maintenance of the senescent state. In particular, we discuss how alterations in mitochondrial metabo