Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ayaka Ito"'
Autor:
Yohei Kanamori, Miyako Tanaka, Michiko Itoh, Kozue Ochi, Ayaka Ito, Isao Hidaka, Isao Sakaida, Yoshihiro Ogawa, Takayoshi Suganami
Publikováno v:
iScience, Vol 24, Iss 2, Pp 102032- (2021)
Summary: Although recent evidence suggests the involvement of iron accumulation in the pathogenesis of nonalcoholic steatohepatitis (NASH), the underlying mechanisms remain poorly understood. Previously, we reported a unique histological structure te
Externí odkaz:
https://doaj.org/article/16a03f7777ad4768bb6009dc684fd2ff
Autor:
Duong Long Duy, Ayaka Ito, Kenji Irie, Kaoru Irie, Tomoaki Mizuno, Yasuyuki Suda, Arvin Lapiz Valderrama, Eri Matsuura, Risa Takeuchi, Shiori Fujii
Publikováno v:
Biochemical and Biophysical Research Communications. 570:125-130
There are two major deadenylase complexes, Ccr4-Not and Pan2-Pan3, which shorten the 3' poly(A) tail of mRNA and are conserved from yeast to human. We have previously shown that the Ccr4-mediated deadenylation plays the important role in gene express
Autor:
Haruka Nasako, Ayaka Ito, Risa Akizuki, Yuta Yoshino, Akira Ikari, Yui Takashina, Satoshi Endo, Hiroaki Eguchi, Toshiyuki Matsunaga
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6582, p 6582 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 12
International Journal of Molecular Sciences
Volume 22
Issue 12
Claudin-2 (CLDN2), a tight junctional protein, is involved in the chemoresistance in a three-dimensional spheroid culture model of human lung adenocarcinoma A549 cells. However, the mechanism has not been fully clarified. We found that the knockdown
Autor:
Chiharu Nishiyama, Kadis Mujiono, Yoshitake Desaki, Akira Nozawa, Takuya Uemura, Keiichirou Nemoto, Ryosuke Hoshino, Ivan Galis, Shigetoshi Miura, Shigeomi Horito, Gen Ichiro Arimura, Makoto Nishiyama, Tatsuya Sawasaki, Ayako Yoshida, Ayaka Ito, Masakazu Hachisu, Yuka Sano
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-11 (2020)
Communications Biology
Communications Biology
Plants respond to herbivory by perceiving herbivore danger signal(s) (HDS(s)), including “elicitors”, that are present in herbivores’ oral secretions (OS) and act to induce defense responses. However, little is known about HDS-specific molecule
Autor:
Aldons J. Lusis, Antonio Castrillo, Xiaohui Wu, Jaspreet S. Sandhu, Bence Daniel, Xin Liu, Kevin Qian, Zhengyi Zhang, Brandon J. Thomas, Stephen T. Smale, Prashant Rajbhandari, Marius Jones, David Salisbury, Julian P. Whitelegge, Cynthia Hong, Ascia Eskin, Laszlo Nagy, Tamer Sallam, Ayaka Ito, David Casero, Peter Tontonoz, Thomas Gilliland, Mete Civelek
Publikováno v:
Nature medicine, vol 24, iss 3
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nuclear receptors regulate gene expression in response to environmental cues, but the molecular events governing the cell-type specificity of nuclear receptors remain poorly understood. Here we outline a role for a non-coding RNA in modulating the ce
Autor:
Arvin Lapiz Valderrama, Tomoaki Mizuno, Yasuyuki Suda, Dang Thi Tuong Vi, Eri Matsuura, Ayaka Ito, Shiori Fujii, Kaoru Irie, Ayaka Nishihata, Kenji Irie
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0251456 (2021)
PLoS ONE
PLoS ONE
Pbp1, the yeast ortholog of human Ataxin-2, was originally isolated as a poly(A) binding protein (Pab1)-binding protein. Pbp1 regulates the Pan2-Pan3 deadenylase complex, thereby modulating the mRNA stability and translation efficiency. However, the
Autor:
Ibuki Shirakawa, Hiroya Ohta, Hitoshi Shimano, Takashi Matsuzaka, Yoshihiro Ogawa, Seiichiro Aoe, Yasuyuki Kitaura, Yorihiro Iwasaki, Miyako Tanaka, Ayaka Ito, Hiroshi Arima, Kento Kurita, Takayoshi Suganami
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
A growing body of evidence indicates that cellular metabolism is involved in immune cell functions, including cytokine production. Serine is a nutritionally non-essential amino acid that can be generated by de novo synthesis and conversion from glyci
Autor:
Takayoshi Suganami, Isao Hidaka, Kozue Ochi, Ayaka Ito, Isao Sakaida, Yoshihiro Ogawa, Miyako Tanaka, Yohei Kanamori, Michiko Itoh
Publikováno v:
iScience
iScience, Vol 24, Iss 2, Pp 102032-(2021)
iScience, Vol 24, Iss 2, Pp 102032-(2021)
Summary Although recent evidence suggests the involvement of iron accumulation in the pathogenesis of nonalcoholic steatohepatitis (NASH), the underlying mechanisms remain poorly understood. Previously, we reported a unique histological structure ter
Autor:
Anna Wilkinson, Yoko Shimizu, Jianjia Fan, Edie Dullaghan, Liisa A.M. Galea, Ayaka Ito, Cheryl L. Wellington, Jeniffer Chan, Peter Tontonoz, Tom A. Pfeifer
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 11, Pp 3139-3150 (2013)
Journal of lipid research, vol 54, iss 11
Journal of lipid research, vol 54, iss 11
Apolipoprotein E (apoE) is the major lipid carrier in the central nervous system. As apoE plays a major role in the pathogenesis of Alzheimer disease (AD) and also mediates repair pathways after several forms of acute brain injury, modulating the exp
Autor:
Orla M. Conneely, Rajendra K. Tangirala, Liming Pei, Ajay Chawla, Ayaka Ito, Ronald M. Evans, Lily C. Chao, Peter Tontonoz, Erin Soto, Cynthia Hong
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 3, Pp 806-815 (2013)
Journal of Lipid Research
Journal of Lipid Research
The formation of the atherosclerotic lesion is a complex process influenced by an array of inflammatory and lipid metabolism pathways. We previously demonstrated that NR4A nuclear receptors are highly induced in macrophages in response to inflammator