Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Amitava Das"'
Publikováno v:
Journal of Cell Communication and Signaling.
Autor:
Sashwati Roy, Amitava Das, Puneet Khandelwal, Savita Khanna, Sangly P. Srinivas, Chandan K. Sen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Scientific Reports
Chronic wounds show necroptosis from which keratinocytes must be protected to enable appropriate wound re-epithelialization and closure. Poloxamers, a class of synthetic triblock copolymers, are known to be effective against plasma membrane damage (P
Autor:
Amitava Das, Subholakshmi Choudhury
Publikováno v:
Cytotherapy. 23:1-9
The inability of two-dimensional cell culture systems to adequately map the structure and function of complex organs like skin necessitates the development of three-dimensional (3D) skin models. A diverse range of 3D skin equivalents have been develo
Autor:
Amitava Das, Komal Kaushik
Publikováno v:
Cytotherapy. 21:1137-1150
Despite advancements in wound care, healing of chronic diabetic wounds remains a great challenge for the clinical fraternity because of the intricacies of the healing process. Due to the limitations of existing treatment strategies for chronic wounds
Publikováno v:
Cellular signalling. 87
Background Triple-negative breast cancer (TNBC) tumors are composed of a heterogeneous population containing both cancer cells and cancer stem cells (CSCs). These CSCs are generated through an epithelial-to-mesenchymal transition (EMT), thus making i
Autor:
Amitava Das, Sandeep P. Bahekar, Kalyan Goswami, Sudhan Debnath, Priyanka Bhoj, Hemant S. Chandak, Kanakaraju Manupati
Publikováno v:
The FEBS Journal. 286:2167-2192
Glutathione S-transferase omega 1 (GSTO1) contributes to the inactivation of a wide range of drug compounds via conjugation to glutathione during phase reactions. Chemotherapy-induced GSTO1 expression in breast cancer cells leads to chemoresistance a
Autor:
Scott Chaffee, Chandan K. Sen, Shomita S. Mathew-Steiner, Sashwati Roy, Natalia Higuita-Castro, Piya Das Ghatak, Raafat A. Anani, Amitava Das, Mohamed S. El Masry
Publikováno v:
The FASEB Journal. 33:2144-2155
Decellularized matrices of biologic tissue have performed well as wound care dressings. Extracellular matrix-based dressings are subject to rapid degradation by excessive protease activity at the wound environment. Stabilized, acellular, equine peric
Autor:
Amitava Das, Mahadeo Gorain, Atul Rawat, Nirupam Biswas, Amit Kumar Madeshiya, Sanskruti P. Mahajan, Nandini Ghosh, Savita Khanna, Chandan K. Sen, Sashwati Roy
Publikováno v:
J Invest Dermatol
Impaired re-epithelialization characterized by hyperkeratotic nonmigratory wound epithelium is a hallmark of nonhealing diabetic wounds. In chronic wounds, the copious release of oncostatin M (OSM) from wound macrophages is evident. OSM is a potent k
Autor:
Lava Timsina, Puneet Khandelwal, Mohamed S. El Masry, Stephen C. Jacobson, Subhadip Ghatak, Amanda P. Siegel, Amitava Das, Mahadeo Gorain, David E. Clemmer, Xuyao Zeng, Sashwati Roy, Robert J. Lee, Brooke A. Brown, Xiaoju Zhou, Andrew G. Clark, Chandan K. Sen, Woran Song, Kanhaiya Singh, Yi Xuan, Mangilal Agarwal, Poornachander R. Guda, Milos V. Novotny
Publikováno v:
ACS Nano
Bidirectional cell-cell communication involving exosome-borne cargo such as miRNA, has emerged as a critical mechanism for wound healing. Unlike other shedding vesicles, exosomes selectively package miRNA by SUMOylation of heterogeneous nuclear ribon
Publikováno v:
Antioxid Redox Signal
Significance: In the host-microbe microenvironment, bioelectrical factors influence microbes and hosts as well as host-microbe interactions. This article discusses relevant mechanistic underpinnings of this novel paradigm. It also addresses how such