Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Amanda B. Muir"'
Autor:
Amanda B. Muir, Jozef Madzo, Karami A, Hugh H. Huang, Kelsey Keith, Kathryn E. Hamilton, Murray Mg, Klochkova A, Mu A, Marie Pier Tetreault, Tatiana A. Karakasheva, Kelly A. Whelan, Jaroslav Jelinek, Kabir Mf, Saxena R, Cruz-Acuna R
Stratified squamous epithelium of the esophagus is comprised of basal keratinocytes that execute a terminal differentiation program in overlying suprabasal and superficial cell layers. Although morphologic progression coupled with expression of speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::466a58736079a723cc38ac10bcd95315
https://doi.org/10.1101/2021.02.08.430312
https://doi.org/10.1101/2021.02.08.430312
Autor:
Kathleen E. Sullivan, Kelly Maurer, Li Song, Jonathan M. Spergel, Melanie A. Ruffner, Joshua X. Wang, Amanda B. Muir, Margaret Carroll, Lihua Shi
Publikováno v:
Allergy
Background Germline-encoded innate immune pattern recognition receptors (PRR) are expressed at epithelial surfaces and modulate epithelial defenses. Evidence suggests that stimulation of the Toll-like receptor (TLR) family of PRR may regulate epithel
Autor:
Bailey Aaron, Masataka Shimonosono, Dominique Bailey, Takeo Hara, Julian A. Abrams, Kathryn E. Hamilton, Yuta Kasagi, Veronique Giroux, Hiroshi Nakagawa, Jonathan M. Spergel, Gary W. Falk, Amanda B. Muir, Tatiana A. Karakasheva, Seema S. Aceves, Kelly A. Whelan, Takashi Kijima, Benjamin J. Wilkins
Publikováno v:
Curr Protoc Stem Cell Biol
The homeostatic proliferation-differentiation gradient in the esophageal epithelium is perturbed under inflammatory disease conditions such as gastroesophageal reflux disease and eosinophilic esophagitis. Herein we describe the protocols for rapid ge
Autor:
Kelly Maurer, Wang Jx, Melanie A. Ruffner, Jonathan M. Spergel, Kathleen E. Sullivan, Amanda B. Muir, Margaret Carroll, Li Song, Shi L
BackgroundA key concept of the hygiene hypothesis is that the microbiome modulates both epithelial barrier integrity as well as host immune responses. Defective expression of tight junction complex proteins alters this homeostatic process, and plays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1641fa336af1d2a04b702dbbfc5bf31a
https://doi.org/10.1101/539759
https://doi.org/10.1101/539759
Autor:
Anna J. Lee, Jonathan M. Spergel, Diana M. Lim, Eduardo Ruchelli, Alain Benitez, Amanda B. Muir, Mei-Lun Wang, Prasanna M. Chandramouleeswaran
Publikováno v:
Experimental Cell Research. 319:850-859
Background Esophageal fibrosis is a complication of eosinophilic esophagitis (EoE) which has been attributed to both subepithelial fibrosis and to epithelial to mesenchymal transition (EMT), a process by which epithelial cells acquire mesenchymal fea
Autor:
Alain Benitez, Benjamin J. Wilkins, Kara K. Dods, Jamie Merves, Jonathan M. Spergel, Jennifer H. Yearley, Yuliana Noah, Anna J. Lee, Mei-Lun Wang, Amanda B. Muir, Prasanna M. Chandramouleeswaran, Rene De Waal Malefyt, Fiona Gambanga, Sarit Toltzis, Hiroshi Nakagawa, Dawen Shen
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150968 (2016)
PLoS ONE
PLoS ONE
Eosinophilic esophagitis (EoE) is a chronic Th2 and food antigen-mediated disease characterized by esophageal eosinophilic infiltration. Thymic stromal lymphopoetin (TSLP), an epithelial derived cytokine which bridges innate and Th2-type adaptive imm
Autor:
Alain Benitez, Medha Sharma, Gary W. Falk, Hiroshi Nakagawa, Jonathan M. Spergel, Kelly A. Whelan, Andres J. Klein-Szanto, Maureen DeMarshall, Amanda B. Muir, Prasanna M. Chandramouleeswaran
Publikováno v:
Gastroenterology. 154:S-108
Autor:
Yuli Noah, Rebecca G. Wells, Kara K. Dods, Gary W. Falk, Hiroshi Nakagawa, Amanda B. Muir, Adam Bedenbaugh, Sarit Toltzis, Alain Benitez, Mei-Lun Wang, Anna Lee, Prasanna M. Chandramouleeswaran
Publikováno v:
Experimental cell research. 330(1)
Eosinophilic esophagitis (EoE) is an allergic inflammatory disease that leads to esophageal fibrosis and stricture. We have recently shown that in EoE, esophageal epithelial cells undergo an epithelial to mesenchymal transition (EMT), characterized b
Publikováno v:
Gastroenterology. 142:S-117
Background and Aims: Subepithelial fibrosis has recently been recognized as a histologic feature of eosinophilic esophagitis (EoE), a chronic inflammatory disease which leads to esophageal stricture, dysphagia, and recurrent food impaction. It is wid