Zobrazeno 1 - 10
of 180
pro vyhledávání: '"11"'
Autor:
John Savill, Graham Thomas, Karen E. Chapman, James S. Gilmour, Hayley J. Harris, Agnes Coutinho, Tak Yung Man, Michael Clay, Jonathan R. Seckl, Jean-François Cailhier, John J. Mullins
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 176(12)
Glucocorticoids promote macrophage phagocytosis of leukocytes undergoing apoptosis. Prereceptor metabolism of glucocorticoids by 11β-hydroxysteroid dehydrogenases (11β-HSDs) modulates cellular steroid action. 11β-HSD type 1 amplifies intracellular
Autor:
Ye Yin, Ling-Dong Kong, Lihong Shen, Ting Fan, Guoliang Deng, Qiang Xu, Xiangbao Meng, Meijing Wang, Yuyu Zhu, Gen-Sheng Feng, Jian Gao, Yang Sun, Shuang Peng, Wenjie Guo, Wen Liu
Publikováno v:
J Biol Chem
Chronic low-grade inflammation plays an important role in the pathogenesis of type 2 diabetes. Src homology 2 domain-containing tyrosine phosphatase-2 (SHP2) has been reported to play diverse roles in different tissues during the development of metab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6610e86566c0160506567b606a25858c
https://europepmc.org/articles/PMC7397102/
https://europepmc.org/articles/PMC7397102/
Autor:
Nadia Rosenthal, Carmine Nicoletti, Aline Villa Nova Bacurau, Emanuele Rizzuto, Laura Barberi, Francesca Ascenzi, Bianca Maria Scicchitano, Gabriella Dobrowolny, Antonio Musarò
Publikováno v:
Aging Cell
The decline in skeletal muscle mass and strength occurring in aging, referred as sarcopenia, is the result of many factors including an imbalance between protein synthesis and degradation, changes in metabolic/hormonal status, and in circulating leve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89aa5278e589ef5cf75ff8cdbdbbbbe9
http://hdl.handle.net/10807/133905
http://hdl.handle.net/10807/133905
Autor:
Maicas, Nuria, van der Vlag, Johan, Bublitz, Janin, Florquin, Sandrine, Bakker-van Bebber, Marinka, Dinarello, Charles A, Verweij, Vivienne, Masereeuw, Roos, Joosten, Leo A, Hilbrands, Luuk B, Afd Pharmacology, Pharmacology
Publikováno v:
PLoS ONE
PLoS One, 12(2). Public Library of Science
PLoS ONE, 12(2). Public Library of Science
PLoS ONE, Vol 12, Iss 2, p e0168981 (2017)
PLoS One, 12, 2
PLoS One, 12
PLoS One, 12(2). Public Library of Science
PLoS ONE, 12(2). Public Library of Science
PLoS ONE, Vol 12, Iss 2, p e0168981 (2017)
PLoS One, 12, 2
PLoS One, 12
Contains fulltext : 169694.pdf (Publisher’s version ) (Open Access) Several lines of evidence have demonstrated the anti-inflammatory and cytoprotective effects of alpha-1-antitrypsin (AAT), the major serum serine protease inhibitor. The aim of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08e7a33153e4bf8added9938e158c8be
https://dspace.library.uu.nl/handle/1874/348253
https://dspace.library.uu.nl/handle/1874/348253
Autor:
Pankaj Sharma, Mrigank Srivastava, Aditi Sharma, Achchhe Lal Vishwakarma, Promod Kumar Agnihotri, Sharad Sharma
Publikováno v:
Journal of Leukocyte Biology. 99:619-628
Eosinophils play a central role in the pathogenesis of tropical pulmonary eosinophilia, a rare, but fatal, manifestation of filariasis. However, no exhaustive study has been done to identify the genes and proteins of eosinophils involved in the patho
The response of the innate immune and cardiovascular systems to LPS in pregnant and nonpregnant mice
Autor:
Masao Takata, Mark R. Johnson, Lydia F Edey, James Leiper, Fabiana Gordon, Julia Zöllner, Kieran P. O'Dea, Laura G. Howe
Sepsis is the leading cause of direct maternal mortality, but there are no data directly comparing the response to sepsis in pregnant and nonpregnant (NP) individuals. This study uses a mouse model of sepsis to test the hypothesis that the cardiovasc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0c96f296b3b076edbb32772eb9a3a4b
http://hdl.handle.net/10044/1/52959
http://hdl.handle.net/10044/1/52959
Autor:
Sheedfar, Fareeba, Sung, Miranda My, Aparicio-Vergara, Marcela, Kloosterhuis, Niels J, Miquilena-Colina, Maria Eugenia, Vargas-Castrillón, Javier, Febbraio, Maria, Jacobs, René L, de Bruin, Alain, Vinciguerra, Manlio, García-Monzón, Carmelo, Hofker, Marten H, Dyck, Jason Rb, Koonen, Debby P Y, LS Pathobiologie, PB TR, Tissue Repair
Publikováno v:
Aging-Us, 6(4), 281-295. Impact Journals LLC
Aging (Albany, N.Y.), 6, 281-95
Aging (Albany NY)
Aging (Albany, N.Y.), 6, 4, pp. 281-95
Aging, 6(4), 281. US Administration on Aging
Scopus-Elsevier
Aging (Albany, N.Y.), 6, 281-95
Aging (Albany NY)
Aging (Albany, N.Y.), 6, 4, pp. 281-95
Aging, 6(4), 281. US Administration on Aging
Scopus-Elsevier
Item does not contain fulltext CD36 has been associated with obesity and diabetes in human liver diseases, however, its role in age-associated nonalcoholic fatty liver disease (NAFLD) is unknown. Therefore, liver biopsies were collected from individu
Autor:
Lydia F Edey, David A. MacIntyre, Kieran P. O'Dea, Bronwen R. Herbert, Mark R. Johnson, Philip R. Bennett, Renyi Hua, Simon N. Waddington, Masao Takata
Inflammation plays a key role in human term and preterm labor (PTL). Intrauterine LPS has been widely used to model inflammation-induced complications of pregnancy, including PTL. It has been shown to induce an intense myometrial inflammatory cell in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a80e0ff4891a2feb175c5bc5d9b2a92
http://hdl.handle.net/10044/1/43812
http://hdl.handle.net/10044/1/43812
Autor:
Zheng Sun, Yuehai Ke, Yuefei Zhang, Yanfeng Huang, Shenlu Qin, Shu Wan, Hongqiang Cheng, Hongcui Liu, Junlin Yao, Yingchun Xu, Chunqi Li, Xue Zhang
Publikováno v:
Cell Death & Disease
Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS), are life-threatening diseases that are associated with high mortality rates due to treatment limitations. Neutrophils play key roles in the pathogenesis of
Publikováno v:
Cell Death & Disease
Mediators produced by the airway epithelium control the activation, recruitment, and survival of pulmonary dendritic cells (DC) that present antigen to CD4(+) T cells during the genesis and exacerbation of allergic asthma. The epithelial-derived acut