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Autor:
Ying Li, Li Wan, Lili Zhang, Zhongling Zhuo, Xuanmei Luo, Jingyi Cui, Ye Liu, Fei Su, Min Tang, Fei Xiao
Publikováno v:
Biochemical and Biophysical Research Communications. 621:67-73
Nonsense-mediated mRNA decay (NMD) and its regulation play an important role in eliminating faulty transcripts and controlling gene expression. However, measuring NMD activity and characterizing its targets remain challenging. In this study, we set o
Autor:
Aung M. Tun, Seth Maliske, Yucai Wang, David J. Inwards, Thomas M. Habermann, Ivana Micallef, Luis Porrata, Jonas Paludo, Jose Villasboas Bisneto, Allison Rosenthal, Mohamed A Kharfan-Dabaja, Stephen M. Ansell, Grzegorz S. Nowakowski, Umar Farooq, Patrick B. Johnston
Publikováno v:
Transplantation and Cellular Therapy. 28:610-617
Patients with newly diagnosed diffuse large B-cell lymphoma (DLBCL) who achieve progression-free survival (PFS) at 24 months (PFS24) after immunochemotherapy (IC) have excellent overall survival (OS) comparable to that of the age- and sex-matched gen
Autor:
Alexander Schenk, Tobias Esser, Sergen Belen, Nadira Gunasekara, Niklas Joisten, Matteo Thomas Winker, Lea Weike, Wilhelm Bloch, Axel Heidenreich, Jan Herden, Heike Löser, Sabine Oganesian, Sebastian Theurich, Carsten Watzl, Philipp Zimmer
Publikováno v:
American journal of physiology, 323(3):C879–C884
The mobilization and activation of natural killer (NK) cells have been proposed as key mechanisms promoting anti-oncogenic effects of physical exercise. Although mouse models have proven that physical exercise recruits NK cells to tumor tissue and in
Publikováno v:
IET Systems Biology. 16:187-200
The development of sequencing technology has promoted the expansion of cancer genome data. It is necessary to identify the pathogenesis of cancer at the molecular level and explore reliable treatment methods and precise drug targets in cancer by iden
Autor:
Sven A. Holcombe, Brian A. Derstine
Publikováno v:
Journal of Anatomy. 241:1344-1356
Rib fractures are a common and serious outcome of blunt thoracic trauma and their likelihood is greater in older individuals. Osteoporotic bone loss is a well-documented aging phenomenon with sex-specific characteristics, but within rib bones, neithe
Autor:
Nicolas Duployez, Laëtitia Largeaud, Matthieu Duchmann, Rathana Kim, Julie Rieunier, Juliette Lambert, Audrey Bidet, Lise Larcher, Jean Lemoine, François Delhommeau, Pierre Hirsch, Laurène Fenwarth, Olivier Kosmider, Justine Decroocq, Anne Bouvier, Yannick Le Bris, Marlène Ochmann, Alberto Santagostino, Lionel Adès, Pierre Fenaux, Xavier Thomas, Jean-Baptiste Micol, Claude Gardin, Raphael Itzykson, Jean Soulier, Emmanuelle Clappier, Christian Recher, Claude Preudhomme, Arnaud Pigneux, Hervé Dombret, Eric Delabesse, Marie Sébert
Publikováno v:
Blood. 140:756-768
DDX41 germline mutations (DDX41MutGL) are the most common genetic predisposition to myelodysplastic syndrome and acute myeloid leukemia (AML). Recent reports suggest that DDX41MutGL myeloid malignancies could be considered as a distinct entity, even
Publikováno v:
Journal of Anatomy. 241:951-965
The cranial casques of modern cassowaries (Casuarius) have long intrigued researchers; however, in-depth studies regarding their morphological variation are scarce. Through visual inspection, it has been recognized that casque variability exists betw
Autor:
Chao Qu, Cui Wang, Hongyan Li, Ying Li, Chao Han, Xiaofeng Tao, Xin Guan, Yejun Zhang, Meng Chen, Jing Liu, Wei Zou
Publikováno v:
Cell Biology International. 46:1759-1774
Glioblastoma (GBM) is a deadly and common primary brain tumor. Poor prognosis is linked to high proliferation and cell heterogeneity. Sex differences may play a role in patient outcome. Previous studies showed that ER-α36, a variant of the estrogen
Publikováno v:
Oxidative Medicine and Cellular Longevity. 2022:1-11
Rosin derivatives such as dehydroabietic acid and dehydroabietic amine belonging to diterpenoids have similar structure with androgen that inhibited the occurrence and development of prostate cancer. In this study, the effects and possible mechanism
Autor:
Natálie Klubíčková, Michael Michal, Abbas Agaimy, Nina Zidar, Michal Pavlovský, Kenji Yorita, Petr Grossmann, Veronika Hájková, Nikola Ptáková, Petr Šteiner, Michal Michal
Publikováno v:
Virchows Archiv. 481:721-729
We report 7 cases of an indolent, variably myxoid tumor of the vocal cords, characterized by overt cellular atypia with large cells containing intranuclear and intracytoplasmic vacuoles, delicate curvilinear vessels, and sparse inflammatory infiltrat