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Publikováno v:
Journal of Cellular and Molecular Medicine. 26:5403-5413
Very few studies have shown the real origin and timing of de novo variants (DNV) implicated in von Willebrand disease (VWD). We investigated four families with type 2 VWD. First, we conducted linkage analysis using single nucleotide variant genotypin
Autor:
Ya-Wen, Lu, Chun-Chin, Chang, Ruey-Hsing, Chou, Yi-Lin, Tsai, Li-Kuo, Liu, Liang-Kung, Chen, Po-Hsun, Huang, Shing-Jong, Lin
Publikováno v:
Aging. 14:8001-8012
Pathological albuminuria (PAU) (urinary albumin creatinine ratio [UACR] ≥30 mg/g) is an independent risk factor of cardiovascular disease. PAU is more prevalent in men than women. We aimed to compare the association of PAU and the early phase of su
Autor:
Sijia Wu, Xiajun Guo, Jia Shang, Yuanyuan Li, Wanglin Dong, Qianwen Peng, Zhenxing Xie, Chaoran Chen
Publikováno v:
Oxidative Medicine and Cellular Longevity. 2022:1-21
Tissue and organ ischemia can lead to cell trauma, tissue necrosis, irreversible damage, and death. While intended to reverse ischemia, reperfusion can further aggravate an ischemic injury (ischemia-reperfusion injury, I/R injury) through a range of
Autor:
Mariana C. S. Mancini, Ana P. Morelli, Matheus B. Severino, Isadora C. B. Pavan, Érika P. Zambalde, Mariana M. Góis, Luiz G. S. da Silva, Nathalia Quintero‐Ruiz, Caio F. Romeiro, Daniel F. G. dos Santos, Rosângela M. N. Bezerra, Fernando M. Simabuco
Publikováno v:
Journal of Cellular Biochemistry. 123:2079-2092
Prostate cancer (PCa) represents the second most common cancer in men and affects millions worldwide. Chemotherapy is a common treatment for PCa but the development of resistance is often a problem during therapy. NRF2 (nuclear factor erythroid 2-rel
Autor:
Brendan J. Houston, Alexandra M. Lopes, Maris Laan, Liina Nagirnaja, Anne E. O'Connor, D. Jo Merriner, Joseph Nguyen, Margus Punab, Antoni Riera-Escamilla, Csilla Krausz, Kenneth Ivan Aston, Donald F. Conrad, Moira K. O'Bryan
Publikováno v:
DEVELOPMENTAL BIOLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Male infertility is a common condition affecting at least 7% of men worldwide and is often genetic in origin. Using whole exome sequencing, we recently discovered three hemizygous, likely damaging variants in DDB1- and CUL4-associated factor 12-like
Autor:
Dahwan Lim, Sein Jin, Ho-Chul Shin, Wantae Kim, Joon Sig Choi, Doo-Byoung Oh, Seung Jun Kim, Jinho Seo, Bonsu Ku
Publikováno v:
Biochemical and Biophysical Research Communications. 625:174-180
Antiapoptotic B-cell lymphoma-2 (Bcl-2) proteins suppress apoptosis by interacting with proapoptotic regulators. They commonly contain a hydrophobic groove where the Bcl-2 homology 3 (BH3) domain of Bcl-2 family members or BH3 domain-containing non-B
Autor:
Kyung Sook Hong, Kassandra Pagan, William Whalen, Rebecca Harris, Jianjun Yang, Heather Stout-Delgado, Soo Jung Cho
Publikováno v:
Am J Respir Cell Mol Biol
Influenza infection induces lung epithelial cell injury via programmed cell death. Glutathione, a potent antioxidant, has been reported to be associated with influenza infection. We hypothesized that lung epithelial cell death during influenza infect
Publikováno v:
Stem Cells Translational Medicine. 11:1103-1112
Patients with severe COVID-19 experience cytokine storm, an uncontrolled upregulation of pro-inflammatory cytokines, which if unresolved leads to acute respiratory distress syndrome (ARDS), organ damage, and death. Treatments with mesenchymal stromal
Autor:
Rima M. Saliba, Amin M. Alousi, Joseph Pidala, Mukta Arora, Stephen R. Spellman, Michael T. Hemmer, Tao Wang, Camille Abboud, Sairah Ahmed, Joseph H. Antin, Amer Beitinjaneh, David Buchbinder, Michael Byrne, Jean-Yves Cahn, Hannah Choe, Rabi Hanna, Peiman Hematti, Rammurti T. Kamble, Carrie L. Kitko, Mary Laughlin, Lazaros Lekakis, Margaret L. MacMillan, Rodrigo Martino, Parinda A. Mehta, Taiga Nishihori, Sagar S. Patel, Miguel-Angel Perales, Hemalatha G. Rangarajan, Olov Ringdén, Joseph Rosenthal, Bipin N. Savani, Kirk R. Schultz, Sachiko Seo, Takanori Teshima, Marjolein van der Poel, Leo F. Verdonck, Daniel Weisdorf, Baldeep Wirk, Jean A. Yared, Jeffrey Schriber, Richard E. Champlin, Stefan O. Ciurea
Publikováno v:
Transplantation and Cellular Therapy, 28(10), 681-693. Elsevier
Post-transplantation cyclophosphamide (PTCy) has been shown to effectively control graft-versus-host disease (GvHD) in haploidentical (Haplo) transplantations. In this retrospective registry study, we compared GvHD organ distribution, severity, and o
Autor:
Jing Chen, Jialin Meng, Yi Liu, Zichen Bian, Qingsong Niu, Junyi Chen, Jun Zhou, Li Zhang, Meng Zhang, Chaozhao Liang
Publikováno v:
Journal of Cellular and Molecular Medicine. 26:5379-5390
To identify prostate cancer (PCa) patients with a high risk of recurrence is critical before delivering adjuvant treatment. We developed a classifier based on the Enzalutamide treatment resistance-related genes to assist the currently available stagi