Zobrazeno 41 - 50
of 131 951
pro vyhledávání: ''
Autor:
Raymond Kiu, Alexander G. Shaw, Kathleen Sim, Antia Acuna-Gonzalez, Christopher A. Price, Harley Bedwell, Sally A. Dreger, Wesley J. Fowler, Emma Cornwell, Derek Pickard, Gusztav Belteki, Jennifer Malsom, Sarah Phillips, Gregory R. Young, Zoe Schofield, Cristina Alcon-Giner, Janet E. Berrington, Christopher J. Stewart, Gordon Dougan, Paul Clarke, Gillian Douce, Stephen D. Robinson, J. Simon Kroll, Lindsay J. Hall
Clostridium perfringens is an anaerobic toxin-producing bacterium associated with intestinal diseases, particularly in neonatal humans and animals. Infant gut microbiome studies have recently indicated a link between C. perfringens and the preterm in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c99cb2b07e2fd2a5bdf9eb9e6d97321b
https://www.repository.cam.ac.uk/handle/1810/350553
https://www.repository.cam.ac.uk/handle/1810/350553
Autor:
Yong Fan, René Klinkby Støving, Samar Berreira Ibraim, Tuulia Hyötyläinen, Florence Thirion, Tulika Arora, Liwei Lyu, Evelina Stankevic, Tue Haldor Hansen, Pierre Déchelotte, Tim Sinioja, Oddny Ragnarsdottir, Nicolas Pons, Nathalie Galleron, Benoît Quinquis, Florence Levenez, Hugo Roume, Gwen Falony, Sara Vieira-Silva, Jeroen Raes, Loa Clausen, Gry Kjaersdam Telléus, Fredrik Bäckhed, Matej Oresic, S. Dusko Ehrlich, Oluf Pedersen
Publikováno v:
Fan, Y, Støving, R K, Berreira Ibraim, S, Hyötyläinen, T, Thirion, F, Arora, T, Lyu, L, Stankevic, E, Hansen, T H, Déchelotte, P, Sinioja, T, Ragnarsdottir, O, Pons, N, Galleron, N, Quinquis, B, Levenez, F, Roume, H, Falony, G, Vieira-Silva, S, Raes, J, Clausen, L, Telléus, G K, Bäckhed, F, Oresic, M, Ehrlich, S D & Pedersen, O 2023, ' The gut microbiota contributes to the pathogenesis of anorexia nervosa in humans and mice ', Nature Microbiology, vol. 8, no. 5, pp. 787-802 . https://doi.org/10.1038/s41564-023-01355-5
Fan, Y, Støving, R K, Berreira Ibraim, S, Hyötyläinen, T, Thirion, F, Arora, T, Lyu, L, Stankevic, E, Hansen, T H, Déchelotte, P, Sinioja, T, Ragnarsdottir, O, Pons, N, Galleron, N, Quinquis, B, Levenez, F, Roume, H, Falony, G, Vieira-Silva, S, Raes, J, Clausen, L, Telléus, G K, Bäckhed, F, Oresic, M, Ehrlich, S D & Pedersen, O 2023, ' The gut microbiota contributes to the pathogenesis of anorexia nervosa in humans and mice ', Nature Microbiology, vol. 8, pp. 787–802 . https://doi.org/10.1038/s41564-023-01355-5
Fan, Y, Støving, R K, Berreira Ibraim, S, Hyötyläinen, T, Thirion, F, Arora, T, Lyu, L, Stankevic, E, Hansen, T H, Déchelotte, P, Sinioja, T, Ragnarsdottir, O, Pons, N, Galleron, N, Quinquis, B, Levenez, F, Roume, H, Falony, G, Vieira-Silva, S, Raes, J, Clausen, L, Telléus, G K, Bäckhed, F, Oresic, M, Ehrlich, S D & Pedersen, O 2023, ' The gut microbiota contributes to the pathogenesis of anorexia nervosa in humans and mice ', Nature Microbiology, vol. 8, pp. 787–802 . https://doi.org/10.1038/s41564-023-01355-5
Anorexia nervosa (AN) is an eating disorder with a high mortality. About 95% of cases are women and it has a population prevalence of about 1%, but evidence-based treatment is lacking. The pathogenesis of AN probably involves genetics and various env
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::430cf3fc801d420189d5e915fab90195
https://pure.au.dk/portal/da/publications/the-gut-microbiota-contributes-to-the-pathogenesis-of-anorexia-nervosa-in-humans-and-mice(61744700-9c77-4212-9cdd-db6b69bc1281).html
https://pure.au.dk/portal/da/publications/the-gut-microbiota-contributes-to-the-pathogenesis-of-anorexia-nervosa-in-humans-and-mice(61744700-9c77-4212-9cdd-db6b69bc1281).html
Autor:
Rajan, Venkatraman, Dominic, De Nardo
Publikováno v:
Immunology & Cell Biology. 100:753-756
Publikováno v:
Blood. 140:1837-1844
During hemolysis, erythrophagocytes dispose damaged red blood cells. This prevents the extracellular release of hemoglobin, detoxifies heme, and recycles iron in a linked metabolic pathway. Complementary to this process, haptoglobin and hemopexin sca
Autor:
Chiara Rusconi, Chan Y. Cheah, Toby A. Eyre, David Tucker, Pavel Klener, Eva Giné, Lara Crucitti, Cristina Muzi, Sara Iadecola, Gabriele Infante, Sophie Bernard, Rebecca L. Auer, Chiara Pagani, Monika Duglosz-Danecka, Heidi Mocikova, Tom van Meerten, Emanuele Cencini, Ana Marin-Niebla, Michael E. Williams, Piera Angelillo, Paolo Nicoli, Annalisa Arcari, Lucia Morello, Donato Mannina, Orsola Vitagliano, Roberto Sartori, Annalisa Chiappella, Roberta Sciarra, Piero M. Stefani, Martin Dreyling, John F. Seymour, Carlo Visco
Publikováno v:
Blood, 140(17), 1907-1916. AMER SOC HEMATOLOGY
Central nervous system (CNS) relapse of mantle cell lymphoma (MCL) is a rare phenomenon with dismal prognosis, where no standard therapy exists. Since the covalent Bruton tyrosine kinase (BTK) inhibitor ibrutinib is effective in relapsed/refractory M
Autor:
Paul Milne, Helen J. Blair, Cornelia Eckert, Zoya Kingsbury, Matthew Collin, Anetta Ptasinska, Alex Elder, Roderick Skinner, Janine Stutterheim, Jennifer Becq, Elena Zerkalenkova, Constanze Bonifer, Denis M. Schewe, Peter N. Cockerill, N Martinez-Soria, Oskar A. Haas, Peter Carey, Katarzyna Szoltysek, Deepali Pal, Hesta McNeill, Claus Meyer, Maria Rosaria Imperato, James C. Mulloy, Mark Wunderlich, Catherine Cargo, Paul Evans, Sarah E. Fordham, Shan Lin, Pierre Cauchy, Y Shi, Simon Bailey, Salam A. Assi, Rolf Marschalek, Josef Vormoor, Olaf Heidenreich, A Komkov, Michael J. Thirman, Simon Bomken, Ricky Tirtakusuma, Sirintra Nakjang, Fotini Vogiatzi, James M. Allan, Lisa J. Russell, Jayne Y. Hehir-Kwa, Muzlifah Haniffa, Yulia Olshanskaya, Vasily V. Grinev, Christine J. Harrison, Venetia Bigley, Daniel Williamson, Alex Smith, Natalia Miakova
Publikováno v:
Blood. 140:1875-1890
The fusion gene MLL-AF4 defines a high-risk subtype of pro-B acute lymphoblastic leukaemia. However, relapse can be associated with a switch from acute lymphoblastic to acute myeloid leukaemia. Here we show that these myeloid relapses share oncogene
Autor:
Choudhary, Manish C, Chew, Kara W, Deo, Rinki, Flynn, James P, Regan, James, Crain, Charles R, Moser, Carlee, Hughes, Michael D, Ritz, Justin, Ribeiro, Ruy M, Ke, Ruian, Dragavon, Joan A, Javan, Arzhang Cyrus, Nirula, Ajay, Klekotka, Paul, Greninger, Alexander L, Fletcher, Courtney V, Daar, Eric S, Wohl, David A, Eron, Joseph J, Currier, Judith S, Parikh, Urvi M, Sieg, Scott F, Perelson, Alan S, Coombs, Robert W, Smith, Davey M, Li, Jonathan Z, ACTIV-2/A5401 Study Team
Publikováno v:
Nature microbiology, vol 7, iss 11
Nat Microbiol
Nat Microbiol
SARS-CoV-2 mutations that cause resistance to monoclonal antibody (mAb) therapy have been reported. However, it remains unclear whether in vivo emergence of SARS-CoV-2 resistance mutations alters viral replication dynamics or therapeutic efficacy in
Autor:
Joanne Haney, Swetha Vijayakrishnan, James Streetley, Kieran Dee, Daniel Max Goldfarb, Mairi Clarke, Margaret Mullin, Stephen D. Carter, David Bhella, Pablo R. Murcia
Publikováno v:
Nature Microbiology. 7:1879-1890
Interactions between respiratory viruses during infection affect transmission dynamics and clinical outcomes. To identify and characterize virus-virus interactions at the cellular level, we coinfected human lung cells with influenza A virus (IAV) and
Autor:
Sarah Gooding, Naser Ansari-Pour, Mohammad Kazeroun, Kubra Karagoz, Ann Polonskaia, Mirian Salazar, Evie Fitzsimons, Korsuk Sirinukunwattana, Selina Chavda, Maria Ortiz Estevez, Fadi Towfic, Erin Flynt, William Pierceall, Daniel Royston, Kwee Yong, Karthik Ramasamy, Paresh Vyas, Anjan Thakurta
Publikováno v:
Blood. 140:1816-1821
The acquisition of a multidrug refractory state is a major cause of mortality in myeloma. Myeloma drugs that target the cereblon (CRBN) protein include widely used immunomodulatory drugs (IMiDs), and newer CRBN E3 ligase modulator drugs (CELMoDs), in
Autor:
Jacob D. Soumerai, Allison Rosenthal, Shannon Harkins, Jessica Duffy, Carmen Mecca, Yingbing Wang, Ravinder K. Grewal, Areej R. El-Jawahri, Huiyun Liu, Cedric Menard, Ahmet Dogan, Lei Yang, Lisa M. Rimsza, Kurt Bantilan, Haley Martin, Matthew Lei, Sydney Mohr, Anna Kurilovich, Olga Kudryashova, Ekaterina Postovalova, Valentina Nardi, Jeremy S. Abramson, Roberto Chiarle, Andrew D. Zelenetz, Abner Louissaint
Publikováno v:
Blood. 140:1822-1826