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Autor:
O. Nalcaci, Hanns-Rudolf Paur, Silvia Diabaté, Clarissa Marquardt, Henning Bockhorn, Carsten Weiss, A. Panas, Sonja Mülhopt, Werner Baumann
In cell culture studies, foetal calf serum (FCS) comprising numerous different proteins is added, which might coat the surface of engineered nanomaterials (ENMs) and thus could profoundly alter their biological activities. In this study, a panel of i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0ac3b005a3bed1de912acd448b43311
Autor:
Stephen S. Rich, Donna Neuberg, Michael H. Cho, Bing Yu, Matthew Leventhal, George T. O'Connor, Ani Manichaikul, Weiwei Shi, Lynette M. Sholl, Michael C. Honigberg, Abhishek Niroula, Benjamin L. Ebert, Joselyn Rojas-Quintero, R. Graham Barr, Matthew Moll, Stephanie J. London, L. Adrienne Cupples, Siddhartha Jaiswal, Elizabeth C. Oelsner, Brittany E Sandoval, Pradeep Natarajan, Brian E. Cade, Peter van Galen, Susan Redline, Yohannes Tesfaigzi, Christopher J. Gibson, Stephanie M. Gogarten, COPDGene Study Investigators, Deepti Jain, Adolfo Correa, Bruce D. Levy, Sina A. Gharib, Peter Miller, Kaushik Viswanathan, Caroline A. Owen, Edwin K. Silverman, Lillian Werner, Jerome I. Rotter, Dandi Qiao, Brian C. Miller, Adam S. Sperling, Leslie A. Lange, Alexander G. Bick, Marie McConkey, Vasan S. Ramachandran
Publikováno v:
Blood. 139:357-368
Chronic obstructive pulmonary disease (COPD) is associated with age and smoking, but other determinants of the disease are incompletely understood. Clonal hematopoiesis of indeterminate potential (CHIP) is a common, age-related state in which somatic
Autor:
Ali Shawki, Declan F. McCole, Sarah D Bobardt, Jiang Li, Marianne R. Spalinger, Pritha Chatterjee, Meera G. Nair, Anica Sayoc-Becerra, Meli’sa S. Crawford, Alina N. Santos
Publikováno v:
Mucosal immunology, vol 15, iss 1
Mucosal Immunology
Mucosal Immunology
Macrophages are a heterogeneous population of innate immune cells that are often divided into two major subsets: classically activated, typically pro-inflammatory (M1) macrophages that mediate host defense, and alternatively activated, tolerance-indu
Autor:
Xiaowei Bao, Na Liu, Shao Li, Lunxian Tang, Chunxue Wang, Shumin Xu, Qinshu Meng, Xiandong Liu, Xiaohui Zhou, Dongyang Zhao, Shougang Zhuang, Qianqian Zhang
Publikováno v:
Mediators of Inflammation
Mediators of Inflammation, Vol 2021 (2021)
Mediators of Inflammation, Vol 2021 (2021)
Background: We recently reported the differential circRNAs expression patterns of the pulmonary macrophages in sepsis induced ARDS mice model by microarray analysis; However, their function and hidden molecular mechanism in regulation of macrophage a
Autor:
Matthew J. Sweet, James E. B. Curson, David P. Fairlie, Kaustav Das Gupta, Robert Reid, Ashley Mansell, Denuja Karunakaran, Yizhuo Wang, Rishika Abrol, Divya Ramnath, Antje Blumenthal, Junxian Lim
Publikováno v:
Journal of Leukocyte Biology. 111:327-336
TLRs reprogram macrophage metabolism, enhancing glycolysis and promoting flux through the tricarboxylic acid cycle to enable histone acetylation and inflammatory gene expression. The histone deacetylase (HDAC) family of lysine deacetylases regulates
Autor:
Giorgio Zauli, Barbara Toffoli, Federica Tonon, Veronica Tisato, Bruno Fabris, Paola Secchiero, Stella Bernardi
Publikováno v:
Cell Death and Disease, Vol 12, Iss 12, Pp 1-10 (2021)
Cell Death & Disease
Cell Death & Disease
TNF-related apoptosis-inducing ligand (TRAIL) is a protein that induces apoptosis in cancer cells but not in normal ones, where its effects remain to be fully understood. Previous studies have shown that in high-fat diet (HFD)-fed mice, TRAIL treatme
Autor:
Xiaogang Zhang, Ziyang Chen, Jingping Liu, Hengbiao Sun, Xinyao Li, Jian Tang, Yumei He, Meiqi Chen, Xiaoming Lyu, Zhe Xing, Shaowen Zuo, Mengyu Shi, Shuaijun Lv
Publikováno v:
Journal of Leukocyte Biology. 110:1143-1161
Elimination of the posttraumatic inflammatory response and recovery of homeostasis are crucial for the positive prognosis of trauma patients. Myeloid-derived suppressor cells (MDSCs) are known to play a regulatory role in the posttraumatic immune res
Autor:
Nardhy Gomez-Lopez, Roberto Romero, Jose Galaz, Derek Miller, Meyer Gershater, Kenichiro Motomura, Olesya Plazyo, Valeria Garcia-Flores
Publikováno v:
Biol Reprod
Sterile inflammation is triggered by danger signals, or alarmins, released upon cellular stress or necrosis. Sterile inflammation occurring in the amniotic cavity (i.e. sterile intra-amniotic inflammation) is frequently observed in women with spontan
Autor:
Ram Saran Sethi, David Schneberger, Baljit Singh, Gurpreet Kaur Aulakh, Upkardeep Singh Pandher, Shelley Kirychuk, Brooke Thompson
Publikováno v:
Cell and Tissue Research. 386:637-648
Agricultural workplaces consist of multiple airborne contaminants and inhalation exposures induce respiratory effects in workers. Endotoxin (LPS) and glyphosate are two common airborne contaminants in agricultural environments. We have previously sho
Autor:
Rachel Warren, Gloria S. Pryhuber, Andrew M. Dylag, Jeannie Haak, Min Yee, Michael A. O'Reilly
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
It is well known that supplemental oxygen used to treat preterm infants in respiratory distress is associated with permanently disrupting lung development and the host response to influenza A virus (IAV). However, many infants who go home with normal