Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Chakraborty, A."'
Publikováno v:
Biol Reprod
Estradiol-17β has been shown to promote primordial follicle formation and to involve bone morphogenetic protein 2 (BMP2) as a downstream effector to promote primordial follicle in hamsters. However, the molecular mechanism whereby these factors regu
Autor:
Samantha Pérez Uribe, Luis Aarón Manzanero Cárdenas, Sujay Paul, María Fernanda Ruíz Aguilar, Luis Alberto Bravo Vázquez, Ashutosh Sharma, Samik Chakraborty
Publikováno v:
Biochimie. 187:83-93
MicroRNAs (miRNAs) are small (∼21 nucleotides), endogenous, non-coding RNA molecules implicated in the post-transcriptional gene regulation performed through target mRNA cleavage or translational inhibition. In recent years, several investigations
Autor:
Gavril W. Pasternak, Rahul Jilakara, Ying Xian Pan, Rajendra Uprety, Amanda Hunkele, Kevin Appourchaux, Tao Che, Amal El Daibani, Shainnel O. Eans, Jay P. McLaughlin, Lisa Thammavong, Soumen Chakraborty, Susruta Majumdar, Valerie Le Rouzic, Nitin Nuthikattu
Publikováno v:
ACS Chem Neurosci
Dry leaves of kratom (mitragyna speciosa) are anecdotally consumed as pain relievers and antidotes against opioid withdrawal and alcohol use disorders. There are at least 54 alkaloids in kratom; however, investigations to date have focused around mit
Autor:
Indrajit Poirah, Shrikant Babanrao Kokate, Asima Bhattacharyya, Debashish Chakraborty, Shivaram Prasad Singh, Niranjan Rout, Hassan Ashktorab, Duane T. Smoot, Pragyesh Dixit
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-17 (2021)
Journal of Biomedical Science
Journal of Biomedical Science
Background Helicobacter pylori-mediated gastric carcinogenesis is initiated by a plethora of signaling events in the infected gastric epithelial cells (GECs). The E3 ubiquitin ligase seven in absentia homolog 2 (Siah2) is induced in GECs in response
Autor:
Heather M. Stacy, Susruta Majumdar, Soumen Chakraborty, Jay P. McLaughlin, Lisa L. Wilson, Rajendra Uprety, Chloe A. Simons, Shainnel O. Eans, Thomas J. Cirino
Publikováno v:
Cell Mol Neurobiol
Chronic administration of opioids produces physical dependence and opioid-induced hyperalgesia. Users claim the Thai traditional tea “Kratom” and component alkaloid mitragynine ameliorate opioid withdrawal without increased sensitivity to pain. T
Autor:
Gernot Hahne, Sakshibeedu R. Bharath, Herbert Waldmann, Tom Mejuch, Stéphanie M. Guéret, Axel Pahl, Ernesto Guccione, Hacer Karatas, Haiwei Song, Ajaybabu V. Pobbati, Wanjin Hong, Sayan Chakraborty, Sonja Sievers, Pierre-Alexis Goy
Publikováno v:
ACS Chemical Biology. 14:2909-2921
The transcriptional co-regulators YAP (Yes-associated protein) and TAZ (transcriptional coactivator with PDZ-binding motif) are the vertebrate downstream effectors of the Hippo signaling pathway that controls various physiological and pathological pr
Autor:
Axel Behrens, Atanu Chakraborty, Joerg D. Hoeck, Emma Nye, Clive Da Costa, Gavin Kelly, Markus E. Diefenbacher, Julian Downward, E. Josue Ruiz, Linxiang Lan, Bradley Spencer-Dene, Jean-Pierre David, Eva M. Riising
Publikováno v:
JCI Insight
The AP-1 transcription factor c-Jun is required for Ras-driven tumorigenesis in many tissues and is considered as a classical proto-oncogene. To determine the requirement for c-Jun in a mouse model of K-RasG12D-induced lung adenocarcinoma, we inducib
Autor:
Xi Cheng, Nicole R. Bearss, Cameron G. McCarthy, Camilla F Wenceslau, Saroj Chakraborty, Tao Yang, Matam Vijay-Kumar, Beng San Yeoh, Zachary J Schreckenberger, Blair Mell, Avinash Singh, Bina Joe, Gagandeep Singh
Publikováno v:
JCI Insight
Autophagy has long been associated with longevity, and it is well established that autophagy reverts and prevents vascular deterioration associated with aging and cardiovascular diseases. Currently, our understanding of how autophagy benefits the vas
Autor:
Soumen Chakraborty, Susruta Majumdar, Mark von Zastrow, Nevin A. Lambert, Aashish Manglik, Damien Jullié, Miriam Carolin Stoeber, Joy Li
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol. 9 (2020) pp. 1-20
eLife, Vol 9 (2020)
eLife, Vol. 9 (2020) pp. 1-20
G protein-coupled receptors (GPCRs) signal through allostery, and it is increasingly clear that chemically distinct agonists can produce different receptor-based effects. It has been proposed that agonists selectively promote receptors to recruit one
Autor:
Stefanie Zenker, Thomas Pap, Monika Stoll, Michael Schäfers, Sven Hermann, Corinna Wehmeyer, Sumita Thurainayagam, Christiane Geyer, Thomas Vogl, Viktor Wixler, Selina K. Jorch, Mareike Fröhling, Johannes Roth, Alena Dreiling, Deblina Chakraborty, Simone König, Joachim L. Schultze, Karin Loser, Tomas Leanderson, Peter Paruzel, Stephan Ludwig, Athanasios Stratis, Olympia Papantonopoulou, Tom Völler
Publikováno v:
Journal of Clinical Investigation. 128:1852-1866
Autoimmune diseases, such as psoriasis and arthritis, show a patchy distribution of inflammation despite systemic dysregulation of adaptive immunity. Thus, additional tissue-derived signals, such as danger-associated molecular patterns (DAMPs), are i