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Publikováno v:
Current Protein & Peptide Science. 22:548-558
Post Translational Modification (PTM) is a process in which covalent addition of functional groups on protein occurs to maintain their structure, function and stability. Every PTM process in our living system occurs to enhance the functional diversit
Autor:
Irais Castillo Maldonado, Maira Fernanda Zambrano Carrillo, Dealmy Delgadillo Guzmán, Laura Ernestina Barragán Ledezma Barragán Ledezma, Martha Angelica Quintanar Escorza, Eva Ortega Freyre, Alfredo Tellez Valencia
Publikováno v:
Current Protein & Peptide Science. 22:890-897
Exposure to organophosphorus pesticides is an important public health issue due to a large number of occupationally exposed populations, as well as their effects mainly at the level of the nervous, reproductive, and immune systems. It has been report
Autor:
Ally C. Farrell, Zelda Lichtensztejn, Kirk J. McManus, Michaela C. L. Palmer, Tooba Razi, Nicole M. Neudorf
Publikováno v:
Human Molecular Genetics. 31:1471-1486
Despite the high morbidity and mortality rates associated with colorectal cancer (CRC), the aberrant genes and mechanisms driving CRC pathogenesis remain poorly understood. Chromosome instability (CIN), or ongoing changes in chromosome numbers, is a
Autor:
Iara Viana Vidigal Santana, Rodrigo de Oliveira Cavagna, Pedro De Marchi, Leticia Ferro Leal, Flavio Augusto Ferreira da Silva, Gustavo Noriz Berardinelli, Vinicius Duval da Silva, Eduardo Caetano Albino da Silva, Rui Manuel Reis, Icaro Alves Pinto
Publikováno v:
Pathobiology. 89:101-106
Background: Microsatellite instability (MSI) in non-small cell lung cancer (NSCLC) is uncommon; however, most studies refer to European and Asian populations. There are currently no data on MSI frequency in highly admixed populations, such as the one
Autor:
Se Ra Park, Kinarm Ko, Young Koung Lee, Dae Heon Kim, Hae Kyung Lee, Kisung Ko, Soyeon Oh, Do Sun Kim, Jin Wook Kim, Soon Ju Park, Mi Kyung Kim, Moon-Soo Kim, Ilchan Song, Seungwon Lee
Publikováno v:
Molecules and Cells
Transgenic Arabidopsis thaliana expressing an anti-rabies monoclonal antibody (mAb), SO57, was obtained using Agrobacterium-mediated floral dip transformation. The endoplasmic reticulum (ER) retention signal Lys-Asp-Glu-Leu (KDEL) was tagged to the C
Publikováno v:
DNA and Cell Biology. 40:1261-1277
QKI is a vital regulator in RNA splicing and maturation, but its role in cervical cancer (CC) is little known. In this study, we found that QKI is decreased in human CC, and overexpression of QKI inhibits HeLa cell proliferation and promotes the apop
Publikováno v:
Molecular and Cellular Biochemistry
Rho GTPases are molecular switches that play an important role in regulating the behavior of a variety of tumor cells. RhoA GTPase-activating protein 26 (ARHGAP26) is a GTPase-activating protein and inhibits the activity of Rho GTPases by promoting t
Autor:
Jeon, Sungwon, Blazyte, Asta, Yoon, Changhan, Ryu, Hyojung, Jeon, Yeonsu, Bhak, Youngjune, Bolser, Dan, Manica, Andrea, Shin, Eun-Seok, Cho, Yun Sung, Kim, Byung Chul, Ryoo, Namhee, Choi, Hansol, Bhak, Jong
Publikováno v:
Molecules and Cells
Coronavirus disease, COVID-19 (coronavirus disease 2019), caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), has a higher case fatality rate in European countries than in others, especially East Asian ones. One potential explanat
Publikováno v:
Molecular and Cellular Biochemistry. 477:99-104
Periodontitis is defined as a multifactorial polymicrobial infection accompanied by inflammatory reactions. Porphyromonas gingivalis (Pg) is known as a major pathogen in the initiation and progression of periodontitis, and a major virulence factor is
Autor:
Asim K. Duttaroy, Rahul Mallick
Publikováno v:
Molecular and Cellular Biochemistry
The endothelium acts as the barrier that prevents circulating lipids such as lipoproteins and fatty acids into the arterial wall; it also regulates normal functioning in the circulatory system by balancing vasodilation and vasoconstriction, modulatin