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Autor:
Nicole Mittman, Craig C. Earle, Brian Leber, Dina Khalaf, Mohammed Siddiqui, Matthew C. Cheung, Mitchell Sabloff, Lisa Chodirker, Grace Christou, Qing Li, Eugene Brailovski, Alexandre Mamedov, Anne Parmentier, Ning Liu, Lee Mozessohn, Karen W.L. Yee, Ying Liu, Liying Zhang, Rena Buckstein
Publikováno v:
Annals of Hematology. 101:1023-1030
Background: Observational studies suggest an anti-neoplastic effect associated with statins, metformin, dipeptidyl peptidase-4 inhibitors (DPP4i), while sulfonylureas may have a neutral or detrimental effect. The aim of this study was to determine th
Autor:
Tamihiro Kawakami, Haruki Shida, Daigo Nakazawa, Utano Tomaru, Tatsuro Okano, Sora Takeuchi, Akihiro Ishizu, Takafumi Kadono
Publikováno v:
Pathobiology. 89(1):23-28
Introduction: IgA vasculitis is a systemic disease that results from the entrapment of circulating IgA-containing immune complexes in small-vessel walls in the skin, kidneys, and gastrointestinal tract. An excessive formation of neutrophil extracellu
Publikováno v:
ImmunoHorizons. 5:898-908
Upon injury, inflammation and repair processes are orchestrated to maintain tissue homeostasis. The Wnt ligands play essential roles in cell differentiation and proliferation for tissue repair and regeneration. It is increasingly clear that Wnt ligan
Publikováno v:
Cell Biology International. 46:46-51
Inflammatory bowel disease (IBD) develop as a result of a combination of genetic predisposition, dysbiosis of the gut microbiota, and environmental influences, which is mainly represented by ulcerative colitis (UC) and Crohn's disease (CD). IBDs can
Autor:
Nardhy Gomez-Lopez, Roberto Romero, Jose Galaz, Derek Miller, Meyer Gershater, Kenichiro Motomura, Olesya Plazyo, Valeria Garcia-Flores
Publikováno v:
Biol Reprod
Sterile inflammation is triggered by danger signals, or alarmins, released upon cellular stress or necrosis. Sterile inflammation occurring in the amniotic cavity (i.e. sterile intra-amniotic inflammation) is frequently observed in women with spontan
Publikováno v:
Romanian Journal of Morphology and Embryology
Background Weather a psychological construct or a clinical entity, numerous studies have been focused on the biological link between stress, burnout, and biomarkers. Aim The purpose of our study was to search the existing literature and summarize the
Autor:
Jinghe Zhang, Hong Zhao, Binqing Fu, Peng Peng, Zhigang Tian, Dongyao Wang, Dong Wang, Yiqing Shen, Xiaodong Mei, Qi Zhu, Xiaohu Zheng, Min Huang, Xianxiang Chen, Guiqiang Wang, Wuxiang Guan, Yonggang Zhou
Publikováno v:
Journal of Molecular Cell Biology
Background: The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has gradually become a global public health crisis. Some patients who have recovered from COVID-19 subsequently tested positi
Autor:
Tomohiro Kurosaki, Wataru Ise
Publikováno v:
International Immunology. 33:797-801
Plasma cells are terminally differentiated from activated B cells and are specialized for secreting antibodies, which are essential effector molecules in humoral immunity to neutralize invading pathogens. Upon challenge with T-cell-dependent antigens
Publikováno v:
Molecular and Cellular Biochemistry. 477:99-104
Periodontitis is defined as a multifactorial polymicrobial infection accompanied by inflammatory reactions. Porphyromonas gingivalis (Pg) is known as a major pathogen in the initiation and progression of periodontitis, and a major virulence factor is
Publikováno v:
International Archives of Allergy and Immunology. 183:235-245
Background: Allergic rhinitis (AR) is regarded as one of the most common allergic disease of nasal mucosa affecting many people worldwide. Long noncoding RNAs are critical modulators affecting AR progression, whereas the pathogenesis of Linc00632 in