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Publikováno v:
Current Opinion in Lipidology. 33:39-46
PURPOSE OF REVIEW Over the last two decades, evolving discoveries around angiopoietin-like (ANGPTL) proteins, particularly ANGPTL3, ANGPTL4, and ANGPTL8, have generated significant interest in understanding their roles in fatty acid (FA) metabolism.
Publikováno v:
Current Opinion in Endocrinology, Diabetes & Obesity. 28:222-231
Purpose of review Enteroendocrine cells (EECs) are scattered chemosensory cells in the intestinal epithelium that release hormones with a wide range of actions on intestinal function, food intake and glucose homeostasis. The mechanisms by which gut h
Publikováno v:
Curr Opin Lipidol
Purpose of review The incidence of arterial calcification increases with age, can occur independently of atherosclerosis and hyperlipidemia, contributes to vessel stiffening, and is associated with adverse cardiovascular outcomes. Here, we provide an
Autor:
Nigel Capps, Handrean Soran, Ian McDowell, Andrew Neil, Jackie A. Cooper, Steve E. Humphries, Paul N. Durrington
Publikováno v:
Current Opinion in Lipidology. 31:167-175
Purpose of review The role of non-HDL-C in the identification and management of lipid disorders is not clearly defined, although UK guidelines recommend its wider use in assessing the need for lipid-lowering therapy and as a treatment target. Recent
Autor:
Om P. Ganda
Publikováno v:
Current Opinion in Lipidology. 31:238-245
Purpose of review Substantial risk of ASCVD events persists despite intensive statin therapy and other agents to lower LDL-C. The optimal way to address other elements of dyslipidemia, such as triglyceride-rich particles (TRL) and when to treat has r
Autor:
Bettina Hieronimus, Kimber L. Stanhope
Publikováno v:
Curr Opin Lipidol
Purpose of review Chronic consumption of fructose and fructose-containing sugars leads to dyslipidemia. Apolipoprotein (apo) CIII is strongly associated with elevated levels of triglycerides and cardiovascular disease risk. We reviewed the effects of
Autor:
Jean-Charles Fruchart, Raul D. Santos
Publikováno v:
Current Opinion in Lipidology. 30:419-427
Atherogenic dyslipidaemia, characterized by high plasma triglycerides (a surrogate for triglyceride-rich remnant lipoproteins) and low high-density lipoprotein cholesterol (HDL-C), is prevalent in patients with type 2 diabetes mellitus (T2DM) and con
Publikováno v:
Current Opinion in Lipidology. 30:470-476
To summarize recent data on the role of dyslipidaemia and the benefit from managing this in people with disease of the abdominal aorta and its peripheral branches (peripheral artery disease, PAD).Findings from the Further Cardiovascular Outcomes Rese
Autor:
Soumik BasuRay
Publikováno v:
Journal of Clinical Lipidology. 13:832-838
Background Macroautophagy (or autophagy) is a conserved degradative pathway that breaks down sequestered cytoplasmic proteins and organelles in specialized double-membrane compartments called autophagosomes that fuse with lysosomes. Several proteins
Publikováno v:
Current opinion in lipidology. 32(5)