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Publikováno v:
Bioengineered, Vol 13, Iss 2, Pp 3620-3633 (2022)
Preeclampsia (PE) is a pregnancy disorder characterized by excessive trophoblast cell death. This study aims to explore the exact mechanism of the ubiquitination level of FUN14 domain containing 1 (FUNDC1) in mitophagy and injury in hypoxic trophobla
Autor:
Yanfang Chen, Christine M. Rapp, Christina Borchers, Chad A. Brewer, Ramzi Elased, Jeffrey B. Travers, Azeezat A. Awoyemi, Langni Liu
Publikováno v:
Toxicol Lett
Ethanol has been demonstrated to exert profound effects upon cells and tissues via multiple mechanisms. One recently appreciated means by which cells can communicate with other cells is via the production and release of extracellular vesicles. Though
Publikováno v:
Molecular and Cellular Biochemistry. 477:585-592
OBJECTIVE Endoplasmic reticulum stress (ERS) might play a pivotal role in the persistence of metabolic syndrome (MS). Lipopolysaccharide (LPS) derived from various gram-negative bacteria could result in the ERS. Therefore, we aimed to investigate the
Autor:
Hai Liu, Yiyang Hong, Guanyu Wang, Haozhe Li, Xingjian Dong, Jingjing Tao, Anyong Xie, Yili Feng, Yihong Wang, Zhenyu Liuyang, Qinghua Dong, Jing Zhang, Zhongyang Jiang
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Radiation-induced oral mucositis is a major adverse event of radiotherapy. Severe oral mucositis may cause unwanted interruption in radiotherapy and reduce long-term survival in cancer patients receiving radiotherapy, but until now, there have been n
Autor:
Mashal Z Naqvi, You E Li, Monali Wakle-Prabagaran, Lindsey N Kent, Sophia G Weil, Sarah K. England
Publikováno v:
Biol Reprod
Nuclear factor kappa B (NF-κB) transcriptionally regulates several genes involved in initiating uterine contractions. A key factor controlling NF-κB activity is its translocation to the nucleus. In myometrial smooth muscle cells (MSMCs), this trans
Autor:
Víctor Manuel Mendoza-Núñez, Mariano Zacarías-Flores, Martha A. Sánchez-Rodríguez, Alicia Arronte-Rosales, Elsa Correa-Muñoz
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Oxidative stress (OS) increases during the human aging process, and the sedentary lifestyle could be a prooxidant factor. In this study, we determine the effect of sedentary lifestyle on OS during the aging process in Mexican women. A longitudinal st
Autor:
Evgeny M. Ostrovsky, Zoya V. Letkeman, Evgeniya A. Fedorova, Liliya Yu. Basyreva, T. V. Vakhrusheva, Dmitry I. Maximov, S. A. Gusev, Оleg M. Panasenko
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
An understanding of the consequences of oxidative/halogenative stress triggered by neutrophil activation is impossible without considering NETosis. NETosis, formation of neutrophil extracellular traps (NETs), is known to promote microthrombus formati
Autor:
Yueming Song, Xin He, Xi Yang, Kun Shi, Yong Huang, Juehan Wang, Limin Liu, Ce Zhu, Ganjun Feng, Jingcheng Wang, Leizhen Huang
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Aims. Accumulating evidence reported that the microRNA (miRNA) took an important role in intervertebral disc degeneration (IDD). In this study, we revealed a novel miRNA regulatory mechanism in IDD. Main Methods. The miRNA microarray analyses of huma
Autor:
Răzvan Mihail Pleşea, Pharmacy, Bucharest, Romania, Mircea Liţescu, Mircea Sebastian Şerbănescu, Ioan Cordos, Valentin Titus Grigorean, Iancu Emil Pleşea, Doru Adrian Şeicaru, Mirela Albu, Florentina Gherghiceanu, Oana Mirea
Publikováno v:
Romanian Journal of Morphology and Embryology
Aim: The authors aimed to quantitatively assess the variation with age of three of the main components of the aortic wall, namely elastic fibers (FE) and collagen fibers [FC(COL)], and smooth muscle cells (SMCs). Materials and Methods: Four aortic cr
Publikováno v:
Bioengineered
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 1, Pp 6674-6686 (2021)
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 1, Pp 6674-6686 (2021)
The purpose of this work is to probe into the potential role of long non-coding RNA growth arrest specific transcript 5 (lncGAS5)/ microRNA (miR)-188-5p/SMAD2 axis in MIRI. Through ligating the left anterior descending (LAD) coronary artery, MIRI ani