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Autor:
Yan Xintao, Yi Jiang, Xiaodong Wu, Song Feifei, Pu Dai, Wang Yao, Zhong Jinfeng, Ce Wang, Mengdie Shi, Jianping Qiu, Pei Zhiguo, Yuting Ma
Publikováno v:
Cytometry Part A. 101:311-324
Cell enrichment is a powerful tool in many kinds of cell research, especially in applications with low abundance cell types. In this work, we developed a microfluidic fluorescence activated cell sorting (μFACS) device that is able to perform on-dema
Autor:
Fatemeh Taheri, Soheila Fattahi, Mahdi Ghatrehsamani, Maryam Anjomshoa, Faramarz Mohammad Alibeigi, Nader Bagheri, Hedayatollah Shirzad, Monireh Karimi
Publikováno v:
Int J Exp Pathol
Bladder cancer (BC) is one of the most prevalent cancers around the world and, if not treated well, has high morbidity and mortality. Many studies have indicated that there may be various roles for the aryl hydrocarbon receptor (AHR) in the immune sy
Autor:
Ryusuke Muroya, Mayuko Inoue, Jing Gao, Yudai Tajiri, Koji Okabe, Masashi Shin, Fei Huang, Ryoko Nagano, Kazuhiro Aoki, Takayoshi Yamaza, Yukihiko Tamura, Shinsuke Fujii, Tamotsu Kiyoshima, Miho Matsuda, Toshio Kukita, Kengo Nagata, Eijiro Jimi, Yoshihide Mori, Sakura Chishaki
Publikováno v:
Laboratory Investigation. 101:1475-1483
Oral malignant melanoma, which frequently invades the hard palate or maxillary bone, is extremely rare and has a poor prognosis. Bone morphogenetic protein (BMP) is abundantly expressed in bone matrix and is highly expressed in malignant melanoma, in
Autor:
Adrian Tira, Lela Buckingham
Publikováno v:
Int J Exp Pathol
Glioblastoma (GBM) is a highly malignant primary brain tumour displaying rapid cell proliferation and infiltration. GBM primarily occurs at older age; however, younger populations have also been affected. In GBM and other cancers, genetic and epigene
Autor:
Răzvan Mihail Pleşea, Pharmacy, Bucharest, Romania, Mircea Liţescu, Mircea Sebastian Şerbănescu, Ioan Cordos, Valentin Titus Grigorean, Iancu Emil Pleşea, Doru Adrian Şeicaru, Mirela Albu, Florentina Gherghiceanu, Oana Mirea
Publikováno v:
Romanian Journal of Morphology and Embryology
Aim: The authors aimed to quantitatively assess the variation with age of three of the main components of the aortic wall, namely elastic fibers (FE) and collagen fibers [FC(COL)], and smooth muscle cells (SMCs). Materials and Methods: Four aortic cr
Publikováno v:
Cell and Tissue Research. 386:585-603
The underlying mechanism of the trans-sutural distraction osteogenesis (TSDO) technique as an effective treatment that improves the symptoms of midfacial hypoplasia syndromes is not clearly understood. Increasing findings in the orthopedics field ind
Autor:
Aurelie Pac-Soo, Lin Chen, Daqing Ma, Hailin Zhao, Qian Chen, Shanglong Yao, You Shang, Azeem Alam
Publikováno v:
Laboratory Investigation; a Journal of Technical Methods and Pathology
Epithelial–mesenchymal transition (EMT) plays a crucial role in the development of pulmonary fibrosis. This study aims to investigate the effects of valproic acid (VPA) on EMT in vitro and in vivo. In vitro, EMT was induced by the administration of
Publikováno v:
Laboratory Investigation; a Journal of Technical Methods and Pathology
Uremic toxin accumulation is one possible reason for alterations in hepatic drug metabolism in patients with chronic kidney disease (CKD). However, the types of uremic toxins and underlying mechanisms are poorly understood. In this study, we report t
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-6 (2021)
Acta Neuropathologica Communications
Acta Neuropathologica Communications
Recent studies suggest that brain cell type specific intracellular environments may play important roles in the generation of structurally different protein aggregates that define neurodegenerative diseases. Using human induced pluripotent stem cells
Autor:
Markus Britschgi, Thomas Kremer, Klaus Kaluza, Jeroen Kole, Evelien Timmermans-Huisman, Christina A. Maat, Wagner Zago, Mirko Ritter, Olaf Mundigl, Tim Moors, Robin Barbour, Daniel Niedieker, Samir F. El-Mashtoly, Jeroen J. G. Geurts, Liz Spycher, Melanie N. Hug, Sebastian Dziadek, Klaus Gerwert, Wilma D.J. van de Berg, Sylwia Huber, Dennis Petersen, Daniel Mona
Publikováno v:
Acta Neuropathologica
Moors, T E, Maat, C A, Niedieker, D, Mona, D, Petersen, D, Timmermans-Huisman, E, Kole, J, El-Mashtoly, S F, Spycher, L, Zago, W, Barbour, R, Mundigl, O, Kaluza, K, Huber, S, Hug, M N, Kremer, T, Ritter, M, Dziadek, S, Geurts, J J G, Gerwert, K, Britschgi, M & van de Berg, W D J 2021, ' The subcellular arrangement of alpha-synuclein proteoforms in the Parkinson’s disease brain as revealed by multicolor STED microscopy ', Acta Neuropathologica, vol. 142, no. 3, pp. 423-448 . https://doi.org/10.1007/s00401-021-02329-9
Acta Neuropathologica, 142(3), 423-448. Springer Verlag
Moors, T E, Maat, C A, Niedieker, D, Mona, D, Petersen, D, Timmermans-Huisman, E, Kole, J, El-Mashtoly, S F, Spycher, L, Zago, W, Barbour, R, Mundigl, O, Kaluza, K, Huber, S, Hug, M N, Kremer, T, Ritter, M, Dziadek, S, Geurts, J J G, Gerwert, K, Britschgi, M & van de Berg, W D J 2021, ' The subcellular arrangement of alpha-synuclein proteoforms in the Parkinson’s disease brain as revealed by multicolor STED microscopy ', Acta Neuropathologica, vol. 142, no. 3, pp. 423-448 . https://doi.org/10.1007/s00401-021-02329-9
Acta Neuropathologica, 142(3), 423-448. Springer Verlag
Various post-translationally modified (PTM) proteoforms of alpha-synuclein (aSyn)—including C-terminally truncated (CTT) and Serine 129 phosphorylated (Ser129-p) aSyn—accumulate in Lewy bodies (LBs) in different regions of the Parkinson’s disea