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Publikováno v:
Brazilian Journal of Biology, Vol 84 (2021)
Brazilian Journal of Biology, Volume: 84, Article number: e250151, Published: 22 NOV 2021
Brazilian Journal of Biology v.84 2024
Brazilian Journal of Biology
Instituto Internacional de Ecologia (IIE)
instacron:IIE
Brazilian Journal of Biology, Volume: 84, Article number: e250151, Published: 22 NOV 2021
Brazilian Journal of Biology v.84 2024
Brazilian Journal of Biology
Instituto Internacional de Ecologia (IIE)
instacron:IIE
Mammals have a limited capacity to regenerate their tissues and organs. One of the mechanisms associated with natural regeneration is dedifferentiation. Several small molecules such as vitamin C and growth factors could improve reprogramming efficien
Autor:
Suyanee Thongchot, Supani Duangkaew, Wasan Yotchai, Sorranart Maungsomboon, Rapin Phimolsarnti, Apichat Asavamongkolkul, Peti Thuwajit, Chanitra Thuwajit, Chandhanarat Chandhanayingyong
Publikováno v:
Human Cell. 36:456-467
Tenosynovial giant cell tumor (TGCT) is a mesenchymal tumor derived from the synovium of the tendon sheath and joints, most frequently in the large joints. The standard of care for TGCTs is surgical resection. A new targeting approach for treating TG
Autor:
Toshikage Nagao, Kota Yoshifuji, Daichi Sadato, Yotaro Motomura, Makiko Saito, Kurara Yamamoto, Kouhei Yamamoto, Ayako Nogami
Publikováno v:
Experimental Hematology. 116:37-49
We report the establishment of a novel activated B-cell-like (ABC) diffuse large B-cell lymphoma (DLBCL) cell line, designated as TMD12, from a patient with highly refractory DLBCL. ABC-DLBCL is a subtype with a relatively unfavorable prognosis that
Autor:
Tasuku Nishino, Takaya Abe, Mari Kaneko, Masanao Yokohira, Keiko Yamakawa, Katsumi Imaida, Hiroaki Konishi
Publikováno v:
Biochemical and Biophysical Research Communications. 628:91-97
The adaptor protein GAREM has two subtypes. Each is involved in Erk activation signaling downstream of the cell growth factor receptor in cultured cells. Regarding their role in individual animals, we have previously reported that mice deficient in G
Autor:
Yaping Chen, Xiaofei Zhang
Publikováno v:
Biochemical and Biophysical Research Communications. 625:23-30
TRAF-binding domain-containing protein (TRABID), a member of the OTU deubiquitinase family, has an important role in regulating cellular functions via deubiquitinating substrate proteins such as EZH2 and Jmjd2d. However, the mechanism of its role in
Publikováno v:
Biochemical and Biophysical Research Communications. 622:1-7
Cancer development comprehends changes in cell structural and physical states. Cancer cells are softer than normal cells, produce higher contractile forces, and migrate more easily. While chemotherapy, targets proteins involved in biological behavior
Autor:
Chao Chen, Jing Gao, Dan Chen, Jinyu Liu, Biwei He, Yan Chen, Huijuan Zhang, Xingyu Yang, Weiwei Cheng
Publikováno v:
Cell Cycle. 21:2517-2532
Preeclampsia (PE) is a pregnancy-associated disease that may cause maternal and fetal morbidity and mortality. The dysregulation of microRNAs (miRNAs) and their potential functions has been an important direction for elucidating the mechanism of pree
Autor:
Dusko Ilic, Caroline Ogilvie
Publikováno v:
Stem Cells. 40:791-801
The number of clinical trials using human pluripotent stem cells (hPSC)—both embryonic and induced pluripotent stem cells (hESC/iPSC)—has expanded in the last several years beyond expectations. By the end of 2021, a total of 90 trials had been re
Autor:
Yuki Yoshimatsu, Rei Noguchi, Yooksil Sin, Ryuto Tsuchiya, Takuya Ono, Taro Akiyama, Rumi Nakagawa, Satoshi Kamio, Kaoru Hirabayashi, Iwao Ozawa, Kazutaka Kikuta, Tadashi Kondo
Publikováno v:
Human Cell. 35:1270-1278
Dedifferentiated liposarcoma (DDLPS) is morphologically characterized by well-differentiated liposarcomas associated with high-grade non-lipogenic sarcoma and molecularly characterized by the coamplification of MDM2 and CDK4(12q14-15). DDLPS is highl
Autor:
Yu-Tzu Chan, Ruey-Jen Lin, Ya-Hui Wang, Tsai-Hsien Hung, Yenlin Huang, John Yu, Jyh-Cherng Yu, Alice L. Yu
Publikováno v:
Cell communication and signaling : CCS, vol 21, iss 1
Background Both IGF-1R/PI3K/AKT/mTOR and Hippo pathways are crucial for breast cancer stem cells (BCSCs). However, their interplay remains unclear. Methods Four triple negative breast cancer cell lines derived from CSC of two patient-derived xenograf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::504eaf0c6473ef08c63c3382665c8d1a
https://escholarship.org/uc/item/4fm6220w
https://escholarship.org/uc/item/4fm6220w