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Autor:
Abdolreza Ardeshirylajimi, Zahrasadat Paknejad, Maryam Rezai Rad, Hanieh Nokhbatolfoghahaei, Arash Khojasteh
Publikováno v:
Current stem cell research & therapy
Introduction: It has been shown that mechanical forces can induce or promote osteogenic differentiation as well as remodeling of the new created bone tissues. To apply this characteristic in bone tissue engineering, it is important to know which mech
Publikováno v:
Tissue Engineering Part B: Reviews. 28:966-977
Mesenchymal stem cells (MSCs) have been demonstrated as promising cell sources for tissue regeneration due to their capability of self-regeneration, differentiation and immunomodulation. MSCs also exert extensive paracrine effects through release of
Autor:
Clark A. Bonham, Dharshan Sivaraj, Michael T. Longaker, Jagannath Padmanabhan, Kellen Chen, Dominic Henn, Derrick C. Wan, Michael Januszyk, Artem A. Trotsyuk, Geoffrey C. Gurtner, Michelle Griffin, Hudson Choi Kussie
Publikováno v:
Advances in Wound Care. 11:466-478
Objective: After injury, humans and other mammals heal by forming fibrotic scar tissue with diminished function, and this healing process involves the dynamic interplay between resident cells withi...
Autor:
Navin Gupta, Ryuji Morizane
Publikováno v:
Semin Cell Dev Biol
Kidney organoid technology has led to a renaissance in kidney developmental biology. The complex underpinnings of mammalian kidney development have provided a framework for the generation of kidney cells and tissues from human pluripotent stem cells.
Autor:
Mamta Singla, Michela Bruschi, Nidhi Bhutani, Pranay Agarwal, Constance R. Chu, Fiorella C. Grandi, Neety Sahu
Publikováno v:
Tissue Eng Part A
Mesenchymal stromal cells (MSCs) have been widely investigated for their regenerative capacity, anti-inflammatory properties and beneficial immunomodulatory effects across multiple clinical indications. Nevertheless, their widespread clinical utiliza
Autor:
Laura A. Dada, A. Weng, Satoshi Watanabe, Annette S. Flozak, Monique Hinchcliff, Rogan A. Grant, M. Maciel-Herrerias, G.S. Budinger, Lynn C. Welch, Raul Piseaux Aillon, SeungHye Han, Cara J. Gottardi, Alexander V. Misharin
Publikováno v:
American journal of respiratory cell and molecular biology. 66(5)
Epithelial polyploidization post-injury is a conserved phenomenon, recently shown to improve barrier restoration during wound healing. Whether lung injury can induce alveolar epithelial polyploidy is not known. We show that bleomycin injury induces A
Publikováno v:
Tissue Eng Part A
Failure to regenerate the gradient tendon–bone interface of the enthesis results in poor clinical outcomes for surgical repair. The goal of this study was to evaluate the potential of composite cell sheets for engineering of the tendon–bone inter
Autor:
Fenq-Qi Zhao, Ratan K. Choudhary
Publikováno v:
Current Stem Cell Research & Therapy. 17:207-213
Adult stem cells like mammary and mesenchymal stem cells have received significant attention because these stem cells possess therapeutic potential in treating many animal diseases. These cells can be administered in an autologous or allogenic fashio
Autor:
Markus G. Manz, Dirk Loeffler, Arne Wehling, Florin Schneiter, Tobias Kull, Claudia Lengerke, Timm Schroeder, Weijia Wang
Publikováno v:
Blood, 139 (13)
Blood
Blood
Understanding human hematopoietic stem cell fate control is important for its improved therapeutic manipulation. Asymmetric cell division, the asymmetric inheritance of factors during division instructing future daughter cell fates, was recently desc
Publikováno v:
Seminars in Cell & Developmental Biology. 123:14-21
Postmenopausal osteoporosis is a systemic disease characterized by the loss of bone mass and increased bone fracture risk largely resulting from significantly reduced levels of the hormone estrogen after menopause. Besides the direct negative effects