Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kirsten Lauber"'
Publikováno v:
Radiation Oncology, Vol 15, Iss 1, Pp 1-12 (2020)
Radiat. Oncol. 15:248 (2020)
Radiation Oncology (London, England)
Radiat. Oncol. 15:248 (2020)
Radiation Oncology (London, England)
Background The clonogenic assay is a versatile and frequently used tool to quantify reproductive cell survival in vitro. Current state-of-the-art analysis relies on plating efficiency-based calculations which assume a linear correlation between the n
Autor:
Julia Mayerle, Ahmed Alnatsha, Markus M. Lerch, Georg Beyer, Sebastian Hubertus Maier, Michael Orth, Qi Li, Thomas Marshall, Yonggan Xue, Claus Belka, Prince Allawadhi, Matthias Sendler, Bettina Appel, Julian Peterhansl, Ivonne Regel, Neha Mishra, Jessica Maas, Jens-Peter Kühn, Frank-Ulrich Weiss, Felix Lämmerhirt, Sabine Müller, Kirsten Lauber, Preshit R. Wagh, Ujjwal M. Mahajan
Publikováno v:
Gastroenterology. 161(3)
Backgrounds & Aims Fluoropyrimidine c (5-fluorouracil [5FU]) increasingly represents the chemotherapeutic backbone for neoadjuvant, adjuvant, and palliative treatment of pancreatic ductal adenocarcinoma (PDAC). Even in combination with other agents,
Autor:
Eike Gallmeier, Ana Sofia Cardoso Martins, Kirsten Lauber, Claus Belka, Lars H. Lindner, Dominique Harnicek, Roland Kanaar, Simone Mörtl, Yang Guo, Wolfgang Hiddemann, Roman Hennel, Ulrich Mansmann, Rolf D. Issels, Tomas Hucl, Eric Kampmann
Publikováno v:
International Journal of Cancer. 139:467-479
The tetrahydroisoquinoline trabectedin is a marine compound with approved activity against human soft-tissue sarcoma. It exerts antiproliferative activity mainly by specific binding to the DNA and inducing DNA double-strand breaks (DSB). As homologou
Publikováno v:
Autoimmunity Reviews. 9:425-430
In multicellular organisms apoptotic cells are rapidly and efficiently removed by professional or semi-professional phagocytes. The molecular mechanisms and the key players involved in this highly coordinate process, as well as its immunological outc
Publikováno v:
Apoptosis. 15:1007-1028
Tissue homeostasis in metazoa requires the rapid and efficient clearance of dying cells by professional or semi-professional phagocytes. Impairment of this finely regulated, fundamental process has been implicated in the development of autoimmune dis
Autor:
Christoph Peter, Caius G. Radu, Owen N. Witte, Kirsten Lauber, Sebastian Wesselborg, Li V. Yang, Michaela Waibel, Klaus Schulze-Osthoff
Publikováno v:
Journal of Biological Chemistry. 283:5296-5305
Phagocytosis of apoptotic cells is fundamentally important throughout life, because non-cleared cells become secondarily necrotic and release intracellular contents, thus instigating inflammatory and autoimmune responses. Secreted "find-me" and expos
Autor:
Sebastian Wesselborg, Florian Lang, Joachim Manns, Michaela Waibel, Stefan Kramer, Klaus Schulze-Osthoff, Kirsten Lauber, Adrian Lupescu
Publikováno v:
Apoptosis. 12:623-630
In addition to cell shrinkage, membrane blebbing, DNA fragmentation and phosphatidylserine exposure, intracellular acidification represents a hallmark of apoptosis. Although the mechanisms underlying cytosolic acidification during apoptosis remained
Autor:
Claus Belka, Kirsten Lauber, Erwin Bohn, P. Marini, Sebastian Wesselborg, Shairaz Baksh, Stefan M Kröber, Ralph K. Lindemann, Yi Jin Xiao, Anke Zobywalski, Sibylle G. Blumenthal, Klaus Schulze-Osthoff, Carolin A. Wiedig, Yan Xu, Ingo B. Autenrieth, Gernot Stuhler
Publikováno v:
Cell. 113:717-730
Efficient engulfment of the intact cell corpse is a critical end point of apoptosis, required to prevent secondary necrosis and inflammation. The presentation of “eat-me” signals on the dying cell is an important part of this process of recogniti
Autor:
Kirsten Lauber, Wolfram Brugger, Sebastian Wesselborg, Peter Brossart, Claudio Denzlinger, Frank Grünebach, Alessio Nencioni
Publikováno v:
Experimental Hematology. 30:1020-1028
Objective Dendritic cells (DC) are professional antigen-presenting cells playing a pivotal role in the induction of immunological responses. There is evidence that DC survival during ongoing immune responses is finite. However, little is known about
Autor:
Kirsten Lauber, Ricardo A. Chaurio, Christina Janko, Martin Herrmann, Christian Maueröder, Luis E. Muñoz, Christian Berens
Publikováno v:
Methods in Molecular Biology ISBN: 9781627033824
Apoptosis and necrosis reflect the program of cell death employed by a dying cell and the final stage of death, respectively. Whereas apoptosis is defined as a physiological, highly organized cell death process, necrosis is commonly considered to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c04fcccf636669a4f9bd5ded9e37a7e
https://doi.org/10.1007/978-1-62703-383-1_1
https://doi.org/10.1007/978-1-62703-383-1_1