Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Dechen Jiang"'
Publikováno v:
CCS Chemistry. 4:2221-2227
Electrochemical microscopy has been developed in the past decades for imaging biomolecules in single cells; however, electrochemical visualization of an intracellular protein in one cell is difficu...
Publikováno v:
Analytical Chemistry. 93:7682-7689
Developing an electrochemiluminescence (ECL) coreactant to minimize the biotoxicity and to maximize the enhancement factor is critical to single-cell ECL microscopy. Here, we reported a guanine-rich single-stranded DNA (G-ssDNA)-loaded high-index fac
Publikováno v:
The Analyst. 146:1548-1551
Drop-on-demand microkits with a diameter of ∼20 μm are used to measure the activity of acetylcholinesterase (AChE) in a brain slice with single-cell resolution. The relative standard deviation from 25 cellular regions reached 73.3% exhibiting the
Autor:
Yan-qing Lu, Yifeng Xiong, Wei-Wei Zhao, Nina Wang, Fei Xu, Jiandong Ye, Guang-xing Wu, Qianqian Du, Dan-ran Li, Shulin Gu, Tian-Yang Zhang, Tian Yunfei, Dechen Jiang
The achievement of all-fibre functional nano-modules for subcellular label-free measurement has long been pursued due to the limitations of manufacturing techniques. In this paper, a compact all-fibre label-free nano-sensor composed of a fibre taper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::459703fde7689a7c698573086af064d6
http://arxiv.org/abs/2105.14206
http://arxiv.org/abs/2105.14206
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The quantification of protein activity in individual lysosomes in living cells is realized using a nanocapillary designed to electrochemically analyze internal solution, in which a single lysosome is sorted from the cell and the target p
Publikováno v:
ChemElectroChem. 4:1677-1680
In this communication, active and inactive cholesterol in plasma membrane at one cell were co-measured using luminol electrochemiluminescence so that the composition of active membrane cholesterol was determined at single cells firstly. The cellular
Autor:
Dechen Jiang, Rongrong Pan
The development of more intricate devices for the analysis of enzyme activity in single cells, and even in individual intracellular compartments, would advance the knowledge of cellular heterogeneity and protein function at subcellular locations. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f7fce963d8635e20c80e3d75d23a179
https://doi.org/10.1016/bs.mie.2019.06.015
https://doi.org/10.1016/bs.mie.2019.06.015
Publikováno v:
Analytical biochemistry. 435(2)
In this study, BODIPY-appended calix[4]arene was chosen as a fluorescent probe for intracellular pH. The compound with cell permeability can monitor the minor pH change near neutrality inside the cell and is the first BODIPY-derived probe reported fo
Autor:
Shan Yang, Dechen Jiang, Ryan Phillips, Nancy L. Allbritton, Angie Proctor, Christopher E. Sims
Publikováno v:
Biophysical Journal. 100:217a-218a
Molecularly targeted therapies are at the forefront of clinical science, and are expected to lead to personalization of medical treatments for each patient. Most such therapies are directed at inhibiting specific signal transduction enzymes or pathwa
Autor:
Ryan Phillips, Nancy L. Allbritton, Angie Proctor, Shan Yang, Christopher E. Sims, Dechen Jiang
Publikováno v:
Biophysical Journal. 98:292a
Molecularly targeted therapies are at the forefront of clinical science, and are expected to lead to personalization of medical treatments for each patient. Most such therapies are directed at inhibiting specific signal transduction enzymes or pathwa