Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Yunji Park"'
Autor:
Kun-Joo Lee, Bon-Kyoung Koo, Yunji Park, Seung-Woo Lee, Young-Min Kim, Sang Jun Ha, Sookjin Moon, Ji-Hae Kim, Hyekang Kim, Subin Park, Sumin Hyeon
Publikováno v:
The Journal of Experimental Medicine
Moon et al. report that antigen presentation via MHC II with coreceptor PD-L1 expressed on intestinal epithelial cells is an important contributing factor for the generation of CD4+CD8αα+ intraepithelial lymphocytes.
Conventional CD4+ T cells
Conventional CD4+ T cells
Autor:
Gihoon, You, Yangsoon, Lee, Yeon-Woo, Kang, Han Wook, Park, Kyeongsu, Park, Hyekang, Kim, Young-Min, Kim, Sora, Kim, Ji-Hae, Kim, Dain, Moon, Hyejin, Chung, Wonjun, Son, Ui-Jung, Jung, Eunyoung, Park, Shinai, Lee, Yong-Gyu, Son, Jaehyun, Eom, Jonghwa, Won, Yunji, Park, Jaeho, Jung, Seung-Woo, Lee
Publikováno v:
Science Advances
Tumor-targeted T cell costimulatory antibody augments antitumor immunity by enhancing tumor-killing T cells within the tumor.
Cancer immunotherapy with 4-1BB agonists has limited further clinical development because of dose-limiting toxicity. He
Cancer immunotherapy with 4-1BB agonists has limited further clinical development because of dose-limiting toxicity. He
Autor:
Dong-Hoon Choi, Young Chul Sung, Young Woo Choi, Yunji Park, You Suk Suh, Yong Bok Seo, Moon Cheol Kang, Hong Namkoong, Hyun-Tak Jin, Seung-Woo Lee
Publikováno v:
Clinical Cancer Research. 22:5898-5908
Purpose: The induction of tissue-localized virus-specific CD8 T-cell response is essential for the development of an effective therapeutic vaccine against genital diseases, such as cervical cancer and genital herpes. Here, we aimed to elucidate the i
Autor:
Se Jin Im, Sae Won Kim, Dong-Hoon Choi, Yong Bok Seo, Mi-Young Song, Hong Namkoong, Young Chul Sung, Yunji Park
Publikováno v:
Vaccine. 32:1205-1212
Chemokines have been known to play an important role in eliciting adaptive immune responses by, selectively attracting the innate cellular components to the site of antigen presentation. In this study, we demonstrated that all three CXCR3 ligands, CX
Publikováno v:
BMB Reports
The gastrointestinal tract forms the largest surface in our body with constantly being exposed to various antigens, which provides unique microenvironment for the immune system in the intestine. Accordingly, the gut epithelium harbors the most T lymp
Publikováno v:
The Journal of Immunology. 177:4464-4472
Members of the TNFR family are thought to deliver costimulatory signals to T cells and modulate their function and survival. In this study, we compare the role of two closely related TNFR family molecules, OX40 and 4-1BB, in generating effector CD8 T
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 170(5)
In this study we demonstrate the anti-apoptotic effect of IL-12 and its underlying mechanism in CD8 T cells. The prolonged stimulation of CD8 T cells with anti-CD3 alone caused apoptosis mediated by Fas and the caspase signaling pathway. However, cos