Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Raymond Rothstein"'
Autor:
Michael Oberst, Kim Rosenthal, James Hair, Catherine Auge, Srinath Kasturirangan, Yanan Zheng, Daniel Freeman, Srinivas Mamidi, Shino Hanabuchi, Francis Neal, Amanda Watkins, Clifford Sachs, Raymond Rothstein, Scott A. Hammond, James Moynihan
Publikováno v:
Cancer Research. 78:2775-2775
Targeted immunotherapy utilizing agonist antibodies (Ab) to OX40 shows great promise in preclinical mouse models alone or in combination with various therapies including PD1/PD-L1 antagonist Abs. Ab-mediated signaling through OX40 requires higher-ord
Autor:
Stacy Fuhrmann, Edmund Poon, Erin Sult, Kathy Mulgrew, Robert E. Hollingsworth, Raymond Rothstein, Ross Stewart, Carl Hay, Qihui Huang, Kelly McGlinchey, Scott A. Hammond, Kris Sachsenmeier
Publikováno v:
Cancer Research. 75:285-285
MEDI9447 is a monoclonal antibody specific for the ectoenzyme, CD73. Data is presented in support of the hypothesis that targeting the extracellular production of adenosine by CD73 reduces the immunosuppressive effects of adenosine. We report a range
Autor:
Jonathan Rios-Doria, Jon Chesebrough, Robert E. Hollingsworth, Nicholas Holoweckyj, Nicholas M. Durham, Wei Zhao, Raymond Rothstein, Ching Ching Leow, Leslie Wetzel
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 8, Pp 661-670 (2015)
Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 8, Pp 661-670 (2015)
Based on the previously described roles of doxorubicin in immunogenic cell death, both doxorubicin and liposomal doxorubicin (Doxil) were evaluated for their ability to boost the antitumor response of different cancer immunotherapies including checkp