Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Hans Fritz"'
Autor:
Grety Rihs, Jaroslav Kalvoda, Ivan Earnest, Hans Fritz, Eric Francotte, Manfred Mutter, Christoph Sigel, Fritz Raschdorf, Marcel J. J. Blommers
Publikováno v:
Helvetica Chimica Acta. 76:1539-1563
The 8-amino-5,6,7,8-tetrahydronaphth-2-oic acid (1), 8-(aminomethyl)-5,6,7,8-tetrahydronaphth-2-oic acid (2), and 8-(aminomethyl)naphth-2-oic acid (3) were synthesized in their protected forms as turn-inducing dipeptide mimics.Two of them (2 and 3) w
Publikováno v:
ChemInform. 23
Catalytic double osmylation is described for a series of cyclohexadienes in acetone/H2O in the presence of the co-oxidant N-methylmorpholine N-oxide (NMO). The formation of polyols occurred stereospecifically with cyclohexadienes 3,7, and 11a, leadin
Publikováno v:
Journal of the American Chemical Society. 114:10213-10231
Pentagonal dodecahedranes with four, six, and eight skeletal positions being functionalized are made available from dimethyl 14,19-dioxopagodane-4-syn,9-syn-dicarboxylate 7 as a common precursor. Key steps are the installation of the two carbonyl fun
Autor:
Hans Fritz, Paul R. Spurr, Georg Lutz, Rolf Pinkos, Jürgen Wörth, Bulusu A. R. C. Murty, Horst Prinzbach, Wolf-Dieter Fessner, Lothar Knothe
Publikováno v:
Chemische Berichte. 125:1741-1751
The stepwise route B from pagodanes to dodecahedranes was completed by double catalytic dehydrocyclization of saturated (alkylated) bisseco precursor substrates (2, 3, 5, 16). Based on pagodane, dodecahedranes (9, 10, 13, 14, 17) were obtained in up
Publikováno v:
Helvetica Chimica Acta. 75:1052-1060
Catalytic double osmylation is described for a series of cyclohexadienes in acetone/H2O in the presence of the co-oxidant N-methylmorpholine N-oxide (NMO). The formation of polyols occurred stereospecifically with cyclohexadienes 3,7, and 11a, leadin
Publikováno v:
Helvetica Chimica Acta. 74:1095-1101
On the Synthesis of Derivatives of Pyrido[1,2-a]lazepine The conjugated pyridinium ylides of type 4 undergo 8π -electrocyclisation affording the heterobicyclic allenes 5 which, in the presence of H2O and H2O2, are subsequently transformed into the s
Publikováno v:
Angewandte Chemie International Edition in English. 29:95-99
Autor:
Werner Machleidt, Hans Fritz, Irmgard Assfalg-Machleidt, Dietmar Pfeiler, Marianne Jochum, Amaury Ernesto Fernandez-Montalvan
The ubiquitous μ- and m-calpains are Ca2+-dependent cysteine proteases. They are activated via rearrangement of the catalytic domain II induced by cooperative binding of Ca2+ to several sites of the molecule. Based on the crystallographic structures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6298372c4b23cb60da653afcbda2529b
https://europepmc.org/articles/PMC1133818/
https://europepmc.org/articles/PMC1133818/
Autor:
Hans Fritz, Dusica Gabrijelcic-Geiger, Werner Machleidt, Stefan Gross, Milton T. Stubbs, Beatriz García Díaz, Irmgard Assfalg-Machleidt, Nicole Gollmitzer, Ennes A. Auerswald, Dietmar Pfeiler
Publikováno v:
Biological chemistry. 382(1)
Within the cystatin superfamily, only kininogen domain 2 (KD2) is able to inhibit mu- and m-calpain. In an attempt to elucidate the structural requirements of cystatins for calpain inhibition, we constructed recombinant hybrids of human stefin B (an
Publikováno v:
Helvetica Chimica Acta. 61:661-668
Effect of the Orientation of Substituents on the Chemical Shift of 13 II. 13C-NMR. Study of Substituted Spiro [cyclopropane-1′, 9-fluorenes] The 13C-NMR. spectra of spiro[cyclopropane-1′, 9-fluorenes] substituted at the cyclopropane ring have bee