Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Guy, J."'
Autor:
Ye Zheng, Luiz C. A. Barbosa, Jaime A. Martinez-Acosta, Mohammed Khimji, Guy J. Clarkson, Martin Wills
Publikováno v:
ChemCatChem. 13:4384-4391
A range of ketones flanked by a combination of an aromatic and a heterocyclic ring (furan, thiophene, N -methylimidazole) were reduced under asymmetric transfer hydrogenation (ATH) conditions. Using a range of [(arene)Ru(TsDPEN)Cl] precatalysts, incl
Publikováno v:
Dalton transactions (Cambridge, England : 2003). 51(35)
The synthesis of a range of N-(heterocyclesulfonyl)-functionalised Noyori–Ikariya catalysts is described. The complexes were prepared through a short sequence from C2-symmetric 1,2-diphenylethylene-1,2-diamine (DPEN) and were characterised by a ran
Autor:
Clément Soulié, Jana Kasparkova, Cinzia Imberti, Viktor Brabec, Guy J. Clarkson, Huayun Shi, Martin J. Paterson, Olga Novakova, Peter J. Sadler
Publikováno v:
Chemistry (Weinheim an Der Bergstrasse, Germany)
Photoactivatable agents offer the prospect of highly selective cancer therapy with low side effects and novel mechanisms of action that can combat current drug resistance. 1,8‐Naphthalimides with their extended π system can behave as light‐harve
Autor:
Feng Chen, Isolda Romero-Canelón, Abraha Habtemariam, Ji-Inn Song, Samya Banerjee, Guy J. Clarkson, Lijiang Song, Ivan Prokes, Peter J. Sadler
We have synthesized a series of novel substituted sulfonyl ethylenediamine (en) RuII arene complexes 1–8 of [(η6-arene)Ru(R1-SO2-EnBz)X], where the arene is benzene, HO(CH2)2O-phenyl or biphenyl (biph), X = Cl or I, and R1 is phenyl, 4-Me-phenyl,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a139dbbea3fa8909157418d138cd8bd
http://wrap.warwick.ac.uk/163316/1/d1dt03856g.pdf
http://wrap.warwick.ac.uk/163316/1/d1dt03856g.pdf
Autor:
Elizabeth M. Bolitho, James P. C. Coverdale, Hannah E. Bridgewater, Guy J. Clarkson, Paul D. Quinn, Carlos Sanchez‐Cano, Peter J. Sadler
Publikováno v:
Angewandte Chemie (International Ed. in English)
Most metallodrugs are prodrugs that can undergo ligand exchange and redox reactions in biological media. Here we have investigated the cellular stability of the anticancer complex [OsII[(η6‐p‐cymene)(RR/SS‐MePh‐DPEN)] [1] (MePh‐DPEN=tosyl
Autor:
Gianluca Accorsi, Guy J. Clarkson, Silvia Venturi, M. Ángeles Farrán, Rosa M. Claramunt, Francesco G. Gatti, Agostina Lina Capodilupo, Salvador Leon Cabanillas
Publikováno v:
New Journal of Chemistry. 45:12471-12478
Photoisomerization of trifluoroacetylated diaryl hydrazones induces a change in color due to the formation of a new hydrogen bond in solution and in the solid state.
Publikováno v:
Angewandte Chemie (International Ed. in English)
The sulfone functional group has a strong capacity to direct the asymmetric transfer hydrogenation (ATH) of ketones in the presence of [(arene)Ru(TsDPEN)H] complexes by adopting a position distal to the η6‐arene ring. This preference provides a me
Publikováno v:
Organic Letters. 22:3717-3721
A systematic range of o-hydroxyphenyl ketones were reduced under asymmetric transfer hydrogenation conditions using the C3-tethered catalyst 2. Two directing effects, i.e., an o-hydroxyphenyl coupled to a bulky aromatic on the opposite side of the ke
Autor:
Miles Postings, Samantha L. Shepherd, Roger M. Phillips, Peter Scott, Viktor Brabec, Guy J. Clarkson, Hana Kostrhunova, Nicola J. Rogers, Hualong Song, James P. C. Coverdale
Publikováno v:
Chemical Communications. 56:6392-6395
Functionalised triazole aldehydes are used in the highly selective self-assembly of water-compatible, optically pure, low symmetry Fe(ii)- and Zn(ii)-based metallohelices. Sub-micromolar antiproliferative activity is observed against various cancerou
Publikováno v:
Organic letters. 23(20)
The asymmetric transfer hydrogenation (ATH) of α-keto-1,4-diamides using a tethered Ru/TsDPEN catalyst was achieved in high ee. Studies on derivatives identified the structural elements which lead to the highest enantioselectivities in the products.