Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Gerhard Schenk"'
Publikováno v:
Frontiers in Chemistry, Vol 7 (2019)
Externí odkaz:
https://doaj.org/article/46f985dedc4f466f8718711323e28263
Autor:
Vindi M. Jayasinghe-Arachchige, Leonardo F. Serafim, Qiaoyu Hu, Cihan Ozen, Sreerag N. Moorkkannur, Gerhard Schenk, Rajeev Prabhakar
Publikováno v:
ACS Catalysis. 13:3131-3147
Autor:
Tenuun Bayaraa, Thierry Lonhienne, Samuel Sutiono, Okke Melse, Thomas B. Brück, Esteban Marcellin, Paul V. Bernhardt, Mikael Boden, Jeffrey R. Harmer, Volker Sieber, Luke W. Guddat, Gerhard Schenk
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany).
Enzyme-catalyzed reaction cascades play an increasingly important role for the sustainable manufacture of diverse chemicals from renewable feedstocks. For instance, dehydratases from the ilvD/EDD superfamily have been embedded into a cascade to conve
Autor:
Tenuun Bayaraa, Jose Gaete, Samuel Sutiono, Julia Kurz, Thierry Lonhienne, Jeffrey R. Harmer, Paul V. Bernhardt, Volker Sieber, Luke Guddat, Gerhard Schenk
Publikováno v:
Chemistry – A European Journal. 28
There is an urgent global need for the development of novel therapeutics to combat the rise of various antibiotic-resistant superbugs. Enzymes of the branched-chain amino acid (BCAA) biosynthesis pathway are an attractive target for novel anti-microb
Publikováno v:
Chembiochem : a European journal of chemical biology. 23(10)
The FeS cluster-dependent dihydroxyacid dehydratases (DHADs) and sugar acid-specific dehydratases (DHTs) from the ilvD/EDD superfamily are key enzymes in the bioproduction of a wide variety of chemicals. We analyzed [2Fe-2S]-dependent dehydratases in
Autor:
Ross P. McGeary, Shun Jie Wun, Xin Lin, Gerhard Schenk, Julia L. Kurz, Nicholas P. West, Thierry G. A. Lonhienne, Luke W. Guddat, Waleed M. Hussein, Khushboo M. Patel
Publikováno v:
Chemistry – A European Journal. 27:3130-3141
New drugs aimed at novel targets are urgently needed to combat the increasing rate of drug resistant tuberculosis (TB). Here, the National Cancer Institute Developmental Therapeutic Program (NCI-DTP) chemical library was screened against a promising
Publikováno v:
Journal of Inorganic Biochemistry. 238:112061
Biomimetics hold potential for varied applications in biotechnology and medicine but have also attracted particular interest as benchmarks for the functional study of their more complex biological counterparts, e.g. metalloenzymes. While many of the
Publikováno v:
ACS Catalysis. 10:3684-3696
In this DFT study, the substrate promiscuity of the binuclear [Fe(II)-Zn(II)] core containing glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes has been investigated through the hydrolysis of three chemically diverse groups of substrates: i
Publikováno v:
ACS Catalysis. 10:3110-3118
A high degree of dependence on fossil fuels is one of the major problems faced by modern societies. d-Glucose and glycerol have emerged in recent years as prospective replacements for fossil fuels ...
Publikováno v:
ChemBioChem. 20:1536-1540
Purple acid phosphatases (PAPs) are members of the large family of metallohydrolases, a group of enzymes that perform a wide range of biological functions, while employing a highly conserved catalytic mechanism. PAPs are found in plants, animals and