Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Tilman Kühn"'
Autor:
Eva Ardanaz, Agnetha Linn Rostgaard-Hansen, Alessio Naccarati, Elisabete Weiderpass, Pekka Keski-Rahkonen, Rudolf Kaaks, Tilman Kühn, Anna Winkvist, Jośe Mariá Huerta, H. B. Bueno-De-Mesquita, Guri Skeie, Pietro Ferrari, Krasimira Aleksandrova, Gabriel Perlemuter, Augustin Scalbert, Olatz Mokoroa, Giovanna Tagliabue, Marc J. Gunter, Kim Overvad, José Ramón Quirós, Agneta Kiss, Marie-Christine Boutron-Ruault, Yahya Mahamat-Saleh, Talita Duarte-Salles, Nivonirina Robinot, Anne Tjønneland, Antonia Trichopoulou, Julie A. Schmidt, Christina C. Dahm, Roel Vermeulen, Rosario Tumino, Núria Sala, Joseph A. Rothwell, Sophia Harlid, Magdalena Stepien, Klas Sjöberg, Vivian Viallon, Neil Murphy, Anna Karakatsani, Salvatore Panico, Nicholas J. Wareham, María José Sánchez, Francesca Mancini, Domenico Palli, Mazda Jenab, Elio Riboli, Bodil Ohlsson, Kay-Tee Khaw
Publikováno v:
Stepien, M, Keski-Rahkonen, P, Kiss, A, Robinot, N, Duarte-Salles, T, Murphy, N, Perlemuter, G, Viallon, V, Tjønneland, A, Rostgaard-Hansen, A L, Dahm, C C, Overvad, K, Boutron-Ruault, M-C, Mancini, F R, Mahamat-Saleh, Y, Aleksandrova, K, Kaaks, R, Kühn, T, Trichopoulou, A, Karakatsani, A, Panico, S, Tumino, R, Palli, D, Tagliabue, G, Naccarati, A, Vermeulen, R C H, Bueno-de-Mesquita, H B, Weiderpass, E, Skeie, G, Ramón Quirós, J, Ardanaz, E, Mokoroa, O, Sala, N, Sánchez, M-J, Huerta, J M, Winkvist, A, Harlid, S, Ohlsson, B, Sjöberg, K, Schmidt, J A, Wareham, N, Khaw, K-T, Ferrari, P, Rothwell, J A, Gunter, M, Riboli, E, Scalbert, A & Jenab, M 2021, ' Metabolic perturbations prior to hepatocellular carcinoma diagnosis-Findings from a prospective observational cohort study ', International Journal of Cancer, vol. 148, no. 3, pp. 609-625 . https://doi.org/10.1002/ijc.33236
International Journal of Cancer
International Journal of Cancer, Wiley, 2021, 148 (3), pp.609-625. ⟨10.1002/ijc.33236⟩
Stepien, M, Keski-Rahkonen, P, Kiss, A, Robinot, N, Duarte-Salles, T, Murphy, N, Perlemuter, G, Viallon, V, Tjønneland, A, Rostgaard-Hansen, A L, Dahm, C C, Overvad, K, Boutron-Ruault, M-C, Mancini, F R, Mahamat-Saleh, Y, Aleksandrova, K, Kaaks, R, Kühn, T, Trichopoulou, A, Karakatsani, A, Panico, S, Tumino, R, Palli, D, Tagliabue, G, Naccarati, A, Vermeulen, R C H, Bueno-de-Mesquita, H B, Weiderpass, E, Skeie, G, Ramón Quirós, J, Ardanaz, E, Mokoroa, O, Sala, N, Sánchez, M-J, Huerta, J M, Winkvist, A, Harlid, S, Ohlsson, B, Sjöberg, K, Schmidt, J A, Wareham, N, Khaw, K-T, Ferrari, P, Rothwell, J A, Gunter, M, Riboli, E, Scalbert, A & Jenab, M 2021, ' Metabolic perturbations prior to hepatocellular carcinoma diagnosis : Findings from a prospective observational cohort study ', International Journal of Cancer, vol. 148, no. 3, pp. 609-625 . https://doi.org/10.1002/ijc.33236
International Journal of Cancer, 148(3), 609. Wiley-Liss Inc.
International Journal of Cancer
International Journal of Cancer, Wiley, 2021, 148 (3), pp.609-625. ⟨10.1002/ijc.33236⟩
Stepien, M, Keski-Rahkonen, P, Kiss, A, Robinot, N, Duarte-Salles, T, Murphy, N, Perlemuter, G, Viallon, V, Tjønneland, A, Rostgaard-Hansen, A L, Dahm, C C, Overvad, K, Boutron-Ruault, M-C, Mancini, F R, Mahamat-Saleh, Y, Aleksandrova, K, Kaaks, R, Kühn, T, Trichopoulou, A, Karakatsani, A, Panico, S, Tumino, R, Palli, D, Tagliabue, G, Naccarati, A, Vermeulen, R C H, Bueno-de-Mesquita, H B, Weiderpass, E, Skeie, G, Ramón Quirós, J, Ardanaz, E, Mokoroa, O, Sala, N, Sánchez, M-J, Huerta, J M, Winkvist, A, Harlid, S, Ohlsson, B, Sjöberg, K, Schmidt, J A, Wareham, N, Khaw, K-T, Ferrari, P, Rothwell, J A, Gunter, M, Riboli, E, Scalbert, A & Jenab, M 2021, ' Metabolic perturbations prior to hepatocellular carcinoma diagnosis : Findings from a prospective observational cohort study ', International Journal of Cancer, vol. 148, no. 3, pp. 609-625 . https://doi.org/10.1002/ijc.33236
International Journal of Cancer, 148(3), 609. Wiley-Liss Inc.
International audience; Hepatocellular carcinoma (HCC) development entails changes in liver metabolism. Current knowledge on metabolic perturbations in HCC is derived mostly from case-control designs, with sparse information from prospective cohorts.
Autor:
Karl Smith-Byrne, Agustin Cerani, Florence Guida, Sirui Zhou, Antonio Agudo, Krasimira Aleksandrova, Aurelio Barricarte, Miguel Rodríguez Barranco, Christoph H. Bochers, Inger Torhild Gram, Jun Han, Christopher I. Amos, Rayjean J. Hung, Kjell Grankvist, Therese Haugdhal Nøst, Liher Imaz, María Dolores Chirlaque-López, Mikael Johansson, Rudolf Kaaks, Tilman Kühn, Richard M. Martin, James D. McKay, Valeria Pala, Hilary A. Robbins, Torkjel M. Sandanger, David Schibli, Matthias B. Schulze, Ruth C. Travis, Paolo Vineis, Elisabete Weiderpass, Paul Brennan, Mattias Johansson, J. Brent Richards
Publikováno v:
Cancer Epidemiol Biomarkers Prev
Smith Byrne, K, Martin, R M, Richards, B & Johansson, M 2022, ' Circulating Isovalerylcarnitine and Lung Cancer Risk : Evidence from Mendelian Randomization and Pre-Diagnostic Blood Measurements ', Cancer Epidemiology, Biomarkers and Prevention, vol. 31, no. 10, EPI-21-1033, pp. 1966-1974 . https://doi.org/10.1158/1055-9965.EPI-21-1033
Smith Byrne, K, Martin, R M, Richards, B & Johansson, M 2022, ' Circulating Isovalerylcarnitine and Lung Cancer Risk : Evidence from Mendelian Randomization and Pre-Diagnostic Blood Measurements ', Cancer Epidemiology, Biomarkers and Prevention, vol. 31, no. 10, EPI-21-1033, pp. 1966-1974 . https://doi.org/10.1158/1055-9965.EPI-21-1033
Background: Tobacco exposure causes 8 of 10 lung cancers, and identifying additional risk factors is challenging due to confounding introduced by smoking in traditional observational studies. Materials and Methods: We used Mendelian randomization (MR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97e9faeb07bef8d811adec87c3e5f0f4
https://hdl.handle.net/10037/27964
https://hdl.handle.net/10037/27964
Autor:
Vittorio Krogh, Rudolf Kaaks, Yvonne T. van der Schouw, Gianluca Severi, Eva Ardanaz, Marc J. Gunter, Tilman Kühn, Nicholas J. Wareham, Timothy J. Key, Francesca Mancini, Carlotta Sacerdote, María José Sánchez, Heiner Boeing, Annemieke M.W. Spijkerman, Peter M. Nilsson, Guy Fagherazzi, Miren Dorronsoro, María Dolores Chirlaque, Kay-Tee Khaw, Olov Rolandsson, Stephen J. Sharp, Salvatore Panico, Domenico Palli, Nita G. Forouhi, Christiane S. Hampe, Claudia Langenberg, Kim Overvad, Rosario Tumino, Elio Riboli
Publikováno v:
Rolandsson, O, Hampe, C S, Sharp, S J, Ardanaz, E, Boeing, H, Fagherazzi, G, Mancini, F R, Nilsson, P M, Overvad, K, Chirlaque, M-D, Dorronsoro, M, Gunter, M J, Kaaks, R, Key, T J, Khaw, K-T, Krogh, V, Kühn, T, Palli, D, Panico, S, Sacerdote, C, Sánchez, M-J, Severi, G, Spijkerman, A M W, Tumino, R, van der Schouw, Y T, Riboli, E, Forouhi, N G, Langenberg, C & Wareham, N J 2020, ' Autoimmunity plays a role in the onset of diabetes after 40 years of age ', Diabetologia, vol. 63, no. 2, pp. 266-277 . https://doi.org/10.1007/s00125-019-05016-3
Diabetologia
Diabetologia, Springer Verlag, 2020, 63 (2), pp.266-277. ⟨10.1007/s00125-019-05016-3⟩
Diabetologia, 63, 266. Springer Verlag
Diabetologia
Diabetologia, Springer Verlag, 2020, 63 (2), pp.266-277. ⟨10.1007/s00125-019-05016-3⟩
Diabetologia, 63, 266. Springer Verlag
Aims/hypothesis Type 1 and type 2 diabetes differ with respect to pathophysiological factors such as beta cell function, insulin resistance and phenotypic appearance, but there may be overlap between the two forms of diabetes. However, there are rela
Autor:
Heinz Freisling, Susana Merino, Aurelio Barricarte, Augustin Scalbert, Domenico Palli, Eleni Peppa, Hanna Nyström, Klas Sjöberg, Magdalena Stepien, Antonia Trichopoulou, Aurora Perez-Cornago, Marina Lopez-Nogueroles, Gianluca Severi, Carlotta Sacerdote, Dragos Ciocan, Tilman Kühn, Elisabete Weiderpass, Cosmin Sebastian Voican, Manuela M. Bergmann, Gabriel Perlemuter, Eugene Jansen, Rudolf Kaaks, Michael F. Leitzmann, Julie A. Schmidt, Catherine Dong, Anna Karakatsani, María José Sánchez, Rosario Tumino, Bodil Ohlsson, H. Bas Bueno-de-Mesquita, Marc J. Gunter, Raul Zamora Ros, Guri Skeie, José Mª Huerta, Heiner Boeing, Agustín Lahoz, Vittorio Krogh, Pilar Amiano, Francesca Mancini, Anne Tjønneland, Marie-Christine Boutron-Ruault, Salvatore Panico, Mazda Jenab, Sofia Christakoudi, Vivian Viallon, Renée T. Fortner, Mårten Werner
Publikováno v:
International Journal of Cancer
International Journal of Cancer, Wiley, 2022, 150 (8), pp.1255-1268. ⟨10.1002/ijc.33885⟩
INTERNATIONAL JOURNAL OF CANCER
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Stepien, M, Lopez-Nogueroles, M, Lahoz, A, Kühn, T, Perlemuter, G, Voican, C, Ciocan, D, Boutron-Ruault, M C, Jansen, E, Viallon, V, Leitzmann, M, Tjønneland, A, Severi, G, Mancini, F R, Dong, C, Kaaks, R, Fortner, R T, Bergmann, M M, Boeing, H, Trichopoulou, A, Karakatsani, A, Peppa, E, Palli, D, Krogh, V, Tumino, R, Sacerdote, C, Panico, S, Bueno-de-Mesquita, H B, Skeie, G, Merino, S, Ros, R Z, Sánchez, M J, Amiano, P, Huerta, J M, Barricarte, A, Sjöberg, K, Ohlsson, B, Nyström, H, Werner, M, Perez-Cornago, A, Schmidt, J A, Freisling, H, Scalbert, A, Weiderpass, E, Christakoudi, S, Gunter, M J & Jenab, M 2022, ' Prediagnostic alterations in circulating bile acid profiles in the development of hepatocellular carcinoma ', International Journal of Cancer, vol. 150, no. 8, pp. 599-608 . https://doi.org/10.1002/ijc.33885
International Journal of Cancer, Wiley, 2022, 150 (8), pp.1255-1268. ⟨10.1002/ijc.33885⟩
INTERNATIONAL JOURNAL OF CANCER
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Stepien, M, Lopez-Nogueroles, M, Lahoz, A, Kühn, T, Perlemuter, G, Voican, C, Ciocan, D, Boutron-Ruault, M C, Jansen, E, Viallon, V, Leitzmann, M, Tjønneland, A, Severi, G, Mancini, F R, Dong, C, Kaaks, R, Fortner, R T, Bergmann, M M, Boeing, H, Trichopoulou, A, Karakatsani, A, Peppa, E, Palli, D, Krogh, V, Tumino, R, Sacerdote, C, Panico, S, Bueno-de-Mesquita, H B, Skeie, G, Merino, S, Ros, R Z, Sánchez, M J, Amiano, P, Huerta, J M, Barricarte, A, Sjöberg, K, Ohlsson, B, Nyström, H, Werner, M, Perez-Cornago, A, Schmidt, J A, Freisling, H, Scalbert, A, Weiderpass, E, Christakoudi, S, Gunter, M J & Jenab, M 2022, ' Prediagnostic alterations in circulating bile acid profiles in the development of hepatocellular carcinoma ', International Journal of Cancer, vol. 150, no. 8, pp. 599-608 . https://doi.org/10.1002/ijc.33885
This is the peer reviewed version of the following article: Stepien et.al (2021). Prediagnostic alterations in circulating bile acid profiles in the development of hepatocellular carcinoma. International Journal of Cancer, which has been published in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b6450fced0a81f3f0e91cb9cc64683
https://ora.ox.ac.uk/objects/uuid:441899c5-dec0-42b3-8a85-4446fefb2b52
https://ora.ox.ac.uk/objects/uuid:441899c5-dec0-42b3-8a85-4446fefb2b52
Autor:
Lucía Rizzolo, Victoria Arija, Carlotta Sacerdote, Tilman Kühn, Antonio Agudo, Pilar Amiano, Nasser Laouali, Domenico Palli, Daniel A. Quintana Pacheco, Ramón Quirós, Carmen Santiuste, Emily Sonestedt, Isabel Drake, Elisabete Weiderpass, Lucía Iglesias-Vázquez, Rosario Tumino, Núria Aranda, P Jakszyn, Matthias B. Schulze, Amanda J. Cross, Elom K. Aglago, Eva Ardanaz, Maria Santucci de Magistris, Daniel Redondo-Sánchez
Purpose Excess iron is involved in the development of non-communicable diseases such as cancer, type 2 diabetes and cardiovascular conditions. We aimed to describe the prevalence of excess iron and its determinants in healthy European adults. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa522adf373b04dc0125b1cb3a512c39
https://hdl.handle.net/10668/19842
https://hdl.handle.net/10668/19842
Autor:
Domenico Palli, Marc J. Gunter, Aurora Perez-Cornago, Emily White, Peter T. Campbell, Andrew T. Chan, Lori C. Sakoda, Gad Rennert, Graham Casey, Bethany Van Guelpen, Kala Visvanathan, Loic Le Marchand, Tilman Kühn, David S. Lopez, Anna H. Wu, Amanda J. Cross, Graham G. Giles, P Jakszyn, Hongmei Nan, Sun-Seog Kweon, Stephen B. Gruber, Jenny Chang-Claude, Ulrike Peters, Kimberley Burrows, Linda Snetselaar, Michael Hoffmeister, Bas Bueno-de-Mesquita, Barbara L. Banbury, D. Timothy Bishop, Demetrius Albanes, Georgios Markozannes, Steven Gallinger, John D. Potter, David J. Hunter, Martha L. Slattery, Stephen N. Thibodeau, Wei Zheng, Verena Zuber, Ruth C. Travis, Annika Lindblom, Vicente Martín, Dipender Gill, Sergi Castellví-Bel, Kenneth Offit, Sonja I. Berndt, Temitope O. Keku, Niki Dimou, Ludmila Vodickova, David J. Hughes, Jeanette M. Schenk, Fränzel J.B. Van Duijnhoven, Hansong Wang, Clemens Schafmayer, Cornelia M. Ulrich, Hermann Brenner, Jane C. Figueiredo, Victor Moreno, Timothy J. Key, Juergen Boehm, Richard M. Martin, Paul D.P. Pharoah, Christopher I. Li, Susanna C. Larsson, Stéphane Bézieau, Li Li, Edward Giovannucci, Konstantinos K. Tsilidis, Elizabeth A. Platz, Sarah J Lewis, Volker Arndt, Nikos Papadimitriou, Roger L. Milne, Polly A. Newcomb, Marie-Christine Boutron-Ruault, Alicja Wolk, Sophia Harlid, Jochen Hampe, Heather Hampel, Andrea Gsur, Rami Nassir, Phyllis J. Goodman, Albert de la Chapelle, Neil Murphy, Mark A. Jenkins, Michael O. Woods, Andrea N. Burnett-Hartman, Lihong Qi, Elio Riboli
Publikováno v:
2021, ' Genetically predicted circulating concentrations of micronutrients and risk of colorectal cancer among individuals of European descent : a Mendelian randomization study ', American Journal of Clinical Nutrition, vol. 113, no. 6, nqab003, pp. 1490-1502 . https://doi.org/10.1093/ajcn/nqab003
Am J Clin Nutr
American Journal of Clinical Nutrition
American Journal of Clinical Nutrition, American Society for Nutrition, 2021, 113 (6), pp.1490-1502. ⟨10.1093/ajcn/nqab003⟩
American Journal of Clinical Nutrition 113 (2021) 6
The American journal of clinical nutrition, vol 113, iss 6
American Journal of Clinical Nutrition, 113(6), 1490-1502
Am J Clin Nutr
American Journal of Clinical Nutrition
American Journal of Clinical Nutrition, American Society for Nutrition, 2021, 113 (6), pp.1490-1502. ⟨10.1093/ajcn/nqab003⟩
American Journal of Clinical Nutrition 113 (2021) 6
The American journal of clinical nutrition, vol 113, iss 6
American Journal of Clinical Nutrition, 113(6), 1490-1502
International audience; Background: The literature on associations of circulating concentrations of minerals and vitamins with risk of colorectal cancer is limited and inconsistent. Evidence from randomized controlled trials (RCTs) to support the eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d57e1b0e41a1cbfb85687ded41bc96d
https://hdl.handle.net/1983/81e06b10-55c2-4d9d-8085-77ec1cda1b8a
https://hdl.handle.net/1983/81e06b10-55c2-4d9d-8085-77ec1cda1b8a
Autor:
Charles M. Connolly, Deborah A. Nickerson, Jian Gong, Sébastien Küry, Barbara Pardini, Brent W. Zanke, Andrea Gsur, Jochen Hampe, Coral Arnau-Collell, M. Henar Alonso, Elio Riboli, Annika Lindblom, Ulrike Peters, Gad Rennert, Tabitha A. Harrison, Lori C. Sakoda, Caroline McNeil, Flavio Lejbkowicz, Hyun Min Kang, David J. Hunter, Martha L. Slattery, Miguel Rodríguez-Barranco, Christina Bamia, Satu Männistö, Timothy J. Key, W. James Gauderman, Gonçalo R. Abecasis, Sanford D. Markowitz, Laurence N. Kolonel, Mark A. Jenkins, Yi Lin, Robin Myte, Hedy S. Rennert, Neil Murphy, Antonia Trichopoulou, Christopher I. Li, Ross L. Prentice, Sai Chen, Stephanie J. Weinstein, Kristin E. Anderson, Hua Ling, Mitul Shah, Philipp Hofer, Wen Yi Huang, Sergi Castellví-Bel, Susanna C. Larsson, Maria Dolores Chirlaque, Wei Zheng, Stephanie L. Schmit, Cecelia A. Laurie, Soo-Chin Lee, David Forman, Andrea N. Burnett-Hartman, Giovanna Masala, Sarah C. Nelson, Michael O. Woods, Charles Kooperberg, Qing Zhang, Sonja I. Berndt, Christopher S. Carlson, Katja Butterbach, Hyeong Rok Kim, Rebecca D. Jackson, David Van Den Berg, Michael C. Bassik, Amanda J. Cross, Sushma S. Thomas, Clemens Schafmayer, Anna H. Wu, Douglas F. Easton, Robert W. Haile, Ludmila Vodickova, Graham G. Giles, Yu Ru Su, Jenny Chang-Claude, Lorena Moreno, Peter C. Scacheri, Stefanie Brezina, Min-Ho Shin, Steven Gallinger, Bethany Van Guelpen, Daniel D. Buchanan, Roger L. Milne, Stephen J. Chanock, Tin Louie, Tameka Shelford, Emily White, Kala Visvanathan, Loic Le Marchand, Veronika Vymetalkova, Roxann G. Ingersoll, Temitope O. Keku, Stephanie A. Bien, Fredrick R. Schumacher, Wan-Ling Hsu, Amanda E. Toland, John S. Grove, Noralane M. Lindor, Faye Elliott, Leon Raskin, Heather Hampel, Joshua D. Smith, Vicente Martín, David V. Conti, Sjoerd G. Elias, Henk J. van Kranen, Manish Gala, Daniela Seminara, Syed H.E. Zaidi, Suzanne M. Leal, Tilman Kühn, Korbinian Weigl, Marc J. Gunter, Cornelia M. Ulrich, Peyton Greenside, Victor Moreno, John D. Potter, Michael Hoffmeister, Eric J. Jacobs, Catherine M. Tangen, Jihyoun Jeon, Fränzel J.B. Van Duijnhoven, Andrew T. Chan, Stephen B. Gruber, John A. Baron, Alicja Wolk, Edith J. M. Feskens, Demetrius Albanes, Amit Joshi, Bette J. Caan, Polly A. Newcomb, Stéphane Bézieau, Elizabeth M. Gillanders, Anshul Kundaje, Elizabeth A. Platz, Michael Wainberg, Sun-Seog Kweon, C. Roland Wolf, Gemma Ibáñez-Sanz, Shuji Ogino, Emiko Kobayashi, Richard B. Hayes, Patrick S. Parfrey, Katarina Cuk, Stephen N. Thibodeau, Kenneth Offit, David Duggan, Sophia Harlid, Pavel Vodicka, Juergen Boehm, Christa Stegmaier, Jeroen R. Huyghe, Joseph Vijai, Sang-Hee Cho, Elizabeth W. Pugh, Rachel Pearlman, Alessio Naccarati, Marilena Melas, Graham Casey, Jane Romm, Stephan Buch, Phyllis J. Goodman, Albert de la Chapelle, John L. Hopper, Zsofia K. Stadler, Corinne E. Joshu, Liesel M. FitzGerald, Wolfgang Lieb, Aung Ko Win, Keith R. Curtis, Hermann Brenner, Christopher K. Edlund, Li Hsu, Conghui Qu, Peter T. Campbell, Robert E. Schoen, Heiner Boeing, D. Timothy Bishop, Kimberly F. Doheny, Sabina Sieri, Barbara L. Banbury, Mathieu Lemire, Jane C. Figueiredo, Gregory Idos, Katerina Shulman, Thomas J. Hudson, Melissa C. Southey, Duncan C. Thomas, Paul D.P. Pharoah, Mila Pinchev, Vittorio Perduca, Rocky Fischer, Volker Arndt, William M. Grady, Nasa Sinnott-Armstrong, N. Charlotte Onland-Moret, David M. Levine, Li Li, Dallas R. English
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Nature genetics
Nature Genetics, 51, 76-87
Nature Genetics
Nature Genetics, Nature Publishing Group, 2019, 51 (1), pp.76-87. ⟨10.1038/s41588-018-0286-6⟩
Nature Genetics, 51(1), 76. Nature Publishing Group
Nature Genetics 51 (2018)
Universidad de Barcelona
Nature genetics
Nature Genetics, 51, 76-87
Nature Genetics
Nature Genetics, Nature Publishing Group, 2019, 51 (1), pp.76-87. ⟨10.1038/s41588-018-0286-6⟩
Nature Genetics, 51(1), 76. Nature Publishing Group
Nature Genetics 51 (2018)
To further dissect the genetic architecture of colorectal cancer (CRC), we performed whole-genome sequencing of 1,439 cases and 720 controls, imputed discovered sequence variants and Haplotype Reference Consortium panel variants into genome-wide asso
Autor:
Stephanie J. Weinstein, Rami Nassir, Fredrick R. Schumacher, Neil Murphy, M. Henar Alonso, Satu Männistö, Hedy S. Rennert, Manish Gala, Phyllis J. Goodman, Albert de la Chapelle, Tilman Kühn, Fränzel J.B. Van Duijnhoven, Paul D.P. Pharoah, Anshul Kundaje, Juergen Boehm, W. James Gauderman, Mark A. Jenkins, Vittorio Perduca, Polly A. Newcomb, Amanda I. Phipps, Christopher I. Li, Douglas F. Easton, Antonia Trichopoulou, Kristin E. Anderson, Daniel D. Buchanan, Peter C. Scacheri, William M. Grady, Liher Imaz, Veronika Vymetalkova, Wan-Ling Hsu, Prudence R. Carr, Martha L. Slattery, Keith R. Curtis, Elizabeth A. Platz, Sai Chen, Graham G. Giles, D. Timothy Bishop, David M. Levine, Michael Hoffmeister, Duncan C. Thomas, Roger L. Milne, Michael O. Woods, Michael C. Bassik, Andrea Gsur, Dallas R. English, David V. Conti, Sébastien Küry, Wolfgang Lieb, Jochen Hampe, Coral Arnau-Collell, Steven Gallinger, Emily White, John S. Grove, Antoni Castells, Hermann Brenner, Amanda E. Toland, Noralane M. Lindor, Aurora Perez-Cornago, David Duggan, Temitope O. Keku, Edith J. M. Feskens, Heather Hampel, Korbinian Weigl, Li Li, Li Hsu, Conghui Qu, Peter T. Campbell, John L. Hopper, Volker Arndt, Jenny Chang-Claude, Lorena Moreno, John A. Baron, Stephen N. Thibodeau, Robert E. Schoen, Jeroen R. Huyghe, Rachel Pearlman, Sanford D. Markowitz, Amanda J. Cross, Stephan Buch, Barbara L. Banbury, Thomas J. Hudson, Yu Ru Su, Marc J. Gunter, Stephen B. Gruber, Heiner Boeing, Demetrius Albanes, Wen Yi Huang, Sergi Castellví-Bel, Jane C. Figueiredo, Catherine M. Tangen, Andrew T. Chan, Annika Lindblom, Deborah A. Nickerson, Richard B. Hayes, Lori C. Sakoda, Flavio Lejbkowicz, Salvatore Panico, Alicja Wolk, Kenneth Offit, John D. Potter, Leon Raskin, Bette J. Caan, Clemens Schafmayer, Mingyang Song, Lihong Qi, Elio Riboli, Hyun Min Kang, Sophia Harlid, Pavel Vodicka, Ludmila Vodickova, Cornelia M. Ulrich, Stephanie L. Schmit, Victor Moreno, Anna H. Wu, Brenda Diergaarde, Bethany Van Guelpen, Kala Visvanathan, Loic Le Marchand, Mazda Jenab, Amit Joshi, Stefanie Brezina, Stephanie A. Bien, Charles Kooperberg, Shuji Ogino, Daniela Seminara, Graham Casey, Andrea N. Burnett-Hartman, Robert W. Haile, Ulrike Peters, Gad Rennert, Tabitha A. Harrison, Ross L. Prentice, Yi Lin, Antonio Agudo, Gonçalo R. Abecasis, Sonja I. Berndt, Stephen J. Chanock, Stéphane Bézieau, Patrick S. Parfrey, Richard Barfield, Marie-Christine Boutron-Ruault
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Gut
Gut 70 (2021) 7
Gut, 70(7), 1325-1334
Universidad de Barcelona
Gut
Gut 70 (2021) 7
Gut, 70(7), 1325-1334
ObjectiveAn understanding of the etiologic heterogeneity of colorectal cancer (CRC) is critical for improving precision prevention, including individualized screening recommendations and the discovery of novel drug targets and repurposable drug candi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::848446aa02775ab8c2114dd85e926946
http://hdl.handle.net/2445/179342
http://hdl.handle.net/2445/179342
Autor:
Aurora Perez-Cornago, Dorothee Zoller, Matthias B. Schulze, Eugène H.J.M. Jansen, Gianluca Severi, Jakob Linseisen, Alexandra Nieters, Guri Skeie, Laura De Marco, Antonio Agudo, Mazda Jenab, Sabina Sieri, Elisabete Weiderpass, Rosario Tumino, Marie-Christine Boutron-Ruault, Maria Dolores Chirlaque, Salvatore Panico, Stina Bodén, Maria Wennberg, Tilman Kühn, Roel Vermeulen, Krasimira Aleksandrova, Alicia K Heath, Pilar Amiano, Veronique Chajes, Anne Tjønneland, Veronika Fedirko, Kim Overvad, Giovanna Masala, Marc J. Gunter, Inger T. Gram, Rudolf Kaaks, Christina C. Dahm, Nina Grundmann, María José Sánchez, Elom K. Aglago, Eva Ardanaz, Bas Bueno-de-Mesquita, Joseph A. Rothwell
Publikováno v:
Cancer Epidemiol. Biomarkers Prev. 30, 874-885 (2021)
Linseisen, J, Grundmann, N, Zoller, D, Kuehn, T, Jansen, E H J M, Chajes, V, Fedirko, V, Weiderpass, E, Dahm, C C, Overvad, K, Tjonneland, A, Boutron-Ruault, M-C, Rothwell, J A, Severi, G, Kaaks, R, Schulze, M B, Aleksandrova, K, Sieri, S, Panico, S, Tumino, R, Masala, G, De Marco, L, Bueno-de-Mesquita, B, Vermeulen, R, Gram, I T, Skeie, G, Chirlaque, M-D, Ardanaz, E, Agudo, A, Sánchez, M-J, Amiano, P, Wennberg, M, Bodén, S, Perez-Cornago, A, Aglago, E K, Gunter, M J, Jenab, M, Heath, A K & Nieters, A 2021, ' Red blood cell fatty acids and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) ', Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, vol. 30, no. 5, pp. 874-885 . https://doi.org/10.1158/1055-9965.EPI-20-1426
Cancer Epidemiology Biomarkers and Prevention, 30(5), 874. American Association for Cancer Research Inc.
Linseisen, J, Grundmann, N, Zoller, D, Kühn, T, Jansen, E H J M, Chajès, V, Fedirko, V, Weiderpass, E, Dahm, C C, Overvad, K, Tjønneland, A, Boutron-Ruault, M-C, Rothwell, J A, Severi, G, Kaaks, R, Schulze, M B, Aleksandrova, K, Sieri, S, Panico, S, Tumino, R, Masala, G, De Marco, L, Bueno-de-Mesquita, B, Vermeulen, R, Gram, I T, Skeie, G, Chirlaque, M-D, Ardanaz, E, Agudo, A, Sánchez, M-J, Amiano, P, Wennberg, M, Bodén, S, Perez-Cornago, A, Aglago, E K, Gunter, M J, Jenab, M, Heath, A K & Nieters, A 2021, ' Red Blood Cell Fatty Acids and Risk of Colorectal Cancer in The European Prospective Investigation into Cancer and Nutrition (EPIC) ', Cancer Epidemiology, Biomarkers & Prevention, vol. 30, no. 5, pp. 874-885 . https://doi.org/10.1158/1055-9965.EPI-20-1426
Linseisen, J, Grundmann, N, Zoller, D, Kuehn, T, Jansen, E H J M, Chajes, V, Fedirko, V, Weiderpass, E, Dahm, C C, Overvad, K, Tjonneland, A, Boutron-Ruault, M-C, Rothwell, J A, Severi, G, Kaaks, R, Schulze, M B, Aleksandrova, K, Sieri, S, Panico, S, Tumino, R, Masala, G, De Marco, L, Bueno-de-Mesquita, B, Vermeulen, R, Gram, I T, Skeie, G, Chirlaque, M-D, Ardanaz, E, Agudo, A, Sánchez, M-J, Amiano, P, Wennberg, M, Bodén, S, Perez-Cornago, A, Aglago, E K, Gunter, M J, Jenab, M, Heath, A K & Nieters, A 2021, ' Red blood cell fatty acids and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) ', Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, vol. 30, no. 5, pp. 874-885 . https://doi.org/10.1158/1055-9965.EPI-20-1426
Cancer Epidemiology Biomarkers and Prevention, 30(5), 874. American Association for Cancer Research Inc.
Linseisen, J, Grundmann, N, Zoller, D, Kühn, T, Jansen, E H J M, Chajès, V, Fedirko, V, Weiderpass, E, Dahm, C C, Overvad, K, Tjønneland, A, Boutron-Ruault, M-C, Rothwell, J A, Severi, G, Kaaks, R, Schulze, M B, Aleksandrova, K, Sieri, S, Panico, S, Tumino, R, Masala, G, De Marco, L, Bueno-de-Mesquita, B, Vermeulen, R, Gram, I T, Skeie, G, Chirlaque, M-D, Ardanaz, E, Agudo, A, Sánchez, M-J, Amiano, P, Wennberg, M, Bodén, S, Perez-Cornago, A, Aglago, E K, Gunter, M J, Jenab, M, Heath, A K & Nieters, A 2021, ' Red Blood Cell Fatty Acids and Risk of Colorectal Cancer in The European Prospective Investigation into Cancer and Nutrition (EPIC) ', Cancer Epidemiology, Biomarkers & Prevention, vol. 30, no. 5, pp. 874-885 . https://doi.org/10.1158/1055-9965.EPI-20-1426
Background: A growing body of evidence suggests that alterations of dietary fatty acid (FA) profiles are associated with colorectal cancer risk. However, data from large-scale epidemiologic studies using circulating FA measurements to objectively ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e62b1cf1aed9fdfea9b4a756c786ff2
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=62013
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=62013
Autor:
Renée T. Fortner, Charlotte Le Cornet, Theron Johnson, Tilman Kühn, Rudolf Kaaks, Britta Walter, Ester Herpel, Disorn Sookthai
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-10 (2020)
Breast Cancer Research : BCR
Breast Cancer Research : BCR
Background Experimental and epidemiological studies demonstrate a role for 27-hydroxycholesterol (27HC) in breast cancer development, though results are conflicting. Cholesterol 27-hydroxylase (CYP27A1) and oxysterol 7-alpha-hydroxylase (CYP7B1) regu