Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jun-ichi Iga"'
Autor:
Hiroshi Kumon, Yoshihiro Miyake, Yuta Yoshino, Jun-ichi Iga, Keiko Tanaka, Hidenori Senba, Eizen Kimura, Takashi Higaki, Bunzo Matsuura, Ryuichi Kawamoto, Shu-ichi Ueno
Publikováno v:
Canadian Journal of Diabetes. 46:829-834
The relationship between alanine-glyoxylate aminotransferase 2 (AGXT2) single-nucleotide polymorphisms (SNPs) and diabetes mellitus (DM) has not been investigated. Therefore, we performed a case-control study to examine this relationship.The study su
Autor:
Hiroaki Mori, Masahiro Nomoto, Jun-ichi Iga, Mariko Ueno, Hiroshi Kumon, Masahiro Nagai, Yu Funahashi, Shu-ichi Ueno, Kiyohiro Yamazaki, Takaaki Mori, Yuki Ozaki, Shinichiro Ochi, Yuta Yoshino
Publikováno v:
Journal of Alzheimer's Disease
Background: Phosphatidylinositol-binding clathrin assembly protein (PICALM) is a validated genetic risk factor for late-onset Alzheimer’s disease (AD) and is associated with other neurodegenerative diseases. However, PICALM expression in the blood
Autor:
Shinichiro Ochi, Taku Yoshida, Tomoko Sao, Yoko Mori, Jun-ichi Iga, Takaaki Mori, Kiyohiro Yamazaki, Yuta Yoshino, Yuki Ozaki, Shu-ichi Ueno
Publikováno v:
Journal of Psychiatric Research. 92:74-80
Recent genome-wide association studies revealed that Triggering receptor expressed on myeloid cells 2 (TREM2) was associated with Alzheimer's disease (AD) and other neurodegenerative diseases. We previously reported that TREM2 mRNA is highly expresse
Low methylation rates of dopamine receptor D2 gene promoter sites in Japanese schizophrenia subjects
Autor:
Taku Yoshida, Kentaro Kawabe, Yuta Yoshino, Shusuke Numata, Jun-ichi Iga, Tetsuro Ohmori, Yoko Mori, Shunsuke Nakata, Kiyohiro Yamazaki, Shu-ichi Ueno, Takaaki Mori
Publikováno v:
The World Journal of Biological Psychiatry. 17:449-456
According to the dopamine hypothesis, several studies on the gene for the dopamine receptor D2 (DRD2) have been conducted. However, no trait biomarkers on DRD2 are available. We examined whether the methylation rates in the upstream region of DRD2 in
Autor:
Satsuki Sumitani, Naomi Kameoka, Hiroko Kubo, Shinya Watanabe, Masashi Ohta, Tetsuro Ohmori, Jun-ichi Iga, Chiaki Nakayama-Yamauchi, Masatoshi Inoshita, Masahito Nakataki, Shusuke Numata, Mai Tamaru, Makoto Kinoshita, Hidehiro Umehara, Yasuhiro Funakoshi, Masafumi Harada
Publikováno v:
Journal of affective disorders. 208
Background Previous studies of patients with bipolar disorder (BD) using magnetic resonance spectroscopy (MRS) have shown neurophysiological abnormalities related to the glutamate (Glu)-glutamine (Gln) cycle, membrane turnover, and neuronal integrity
Autor:
Shu-ichi Ueno, Shinya Watanabe, Hongwei Song, Masahito Nakataki, Tetsuro Ohmori, Jun-ichi Iga, Kanami Kodera, Eriko Yoshimoto, Shusuke Numata
Publikováno v:
Neuroscience Letters. 489:126-130
The epithelial membrane protein 1 (EMP1) plays a role in neuronal differentiation and neurite outgrowth, which are involved in the pathogenesis of major depressive disorder (MDD). We sought to determine whether the EMP1 gene is implicated in MDD. We
Autor:
Rosalia A. Teleg, Lillian V. Lee, Hideo Mure, Satoshi Goto, Ryuji Kaji, Ryoma Morigaki, Masahito Nakataki, Jun-ichi Iga, Shinji Nagahiro, Toshitaka Kawarai, Wataru Sako, Ma. Daisy P. Tabuena, Tetsuro Ohmori, Paul Matthew D. Pasco
Publikováno v:
Parkinsonism & Related Disorders. 19:844-846
Autor:
Mitsuo Itakura, Masatoshi Takeda, Kazutaka Ohi, Ryota Hashimoto, Toshihito Tanahashi, Shu-ichi Ueno, Masahito Nakataki, Shusuke Numata, Jun-ichi Iga, Tetsuro Ohmori, Yoshihiro Nakadoi
Publikováno v:
NeuroMolecular Medicine. 12:243-247
Disrupted-in-schizophrenia 1 (DISC1), a known genetic risk factor for schizophrenia (SZ) and major depressive disorder (MDD), interacts with several proteins and some of them are reported to be genetically associated with SZ. Pericentrin (PCNT) also
Autor:
Kyoko Taniguchi, Toshihito Tanahashi, Jun-ichi Iga, Masahito Nakataki, Masahiko Tatsumi, Masahito Tomotake, Tetsuro Ohmori, Mitsuo Itakura, Satsuki Sumitani, Shusuke Numata, Hiroshi Kunugi, Akira Sano, Takashi Asada, Shin'Ya Tayoshi, Yoko Kamegaya, Shu-ichi Ueno
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. :527-534
The phosphodiesterase 4B (PDE4B) interacts with disrupted-in-schizophrenia 1 (DISC1), which is a known genetic risk factor for schizophrenia, bipolar disorder and major depressive disorder (MDD). PDE4B is also important in the regulation of cAMP sign
Autor:
Shusuke Numata, Akira Sano, Tetsuro Ohmori, Shin'Ya Tayoshi, Hongwei Song, Masahito Tomotake, Shu-ichi Ueno, Masahito Nakataki, Satsuki Sumitani, Jun-ichi Iga, Mitsuo Itakura
Publikováno v:
Journal of Psychiatric Research. 43:7-12
The phosphodiesterase 4B (PDE4B) gene is located at 1p31, a susceptibility region for schizophrenia (SZ). Moreover, PDE4B interacts with DISC1, which is a known genetic risk factor for SZ. Recently, it was reported that the PDE4B gene is associated w